Compile Data Set for Download or QSAR
Found 326 with Last Name = 'laffitte' and Initial = 'b'
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Genomics Institute of the Novartis Research Foundation (GNF)

Curated by ChEMBL
LigandPNGBDBM50538098(CHEMBL4640031)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged DYRK1A (1 to 763 residues) expressed in Sf21 cells using Ulight-glycogen synthase as substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WQ079VPubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Genomics Institute of the Novartis Research Foundation (GNF)

Curated by ChEMBL
LigandPNGBDBM50538084(CHEMBL4647659)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of recombinant human DYRK1A (129 to 509 residues) expressed in mammalian expression system by Kinomescan methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WQ079VPubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Genomics Institute of the Novartis Research Foundation (GNF)

Curated by ChEMBL
LigandPNGBDBM50538099(CHEMBL4636064)copy SMILEScopy InChI
Affinity DataIC50: 6.20nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged DYRK1A (1 to 763 residues) expressed in Sf21 cells using Ulight-glycogen synthase as substrate ...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Genomics Institute of the Novartis Research Foundation (GNF)

Curated by ChEMBL
LigandPNGBDBM50538095(CHEMBL4649473)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged DYRK1A (1 to 763 residues) expressed in Sf21 cells using Ulight-glycogen synthase as substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WQ079VPubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Genomics Institute of the Novartis Research Foundation (GNF)

Curated by ChEMBL
LigandPNGBDBM50538090(CHEMBL4648742)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged DYRK1A (1 to 763 residues) expressed in Sf21 cells using Ulight-glycogen synthase as substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WQ079VPubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
GlaxoSmithKline Research and Development

Curated by ChEMBL
LigandPNGBDBM50252816(2-(4-{Butyl[3-(2-hydroxyethoxy)benzyl]amino}phenyl...)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Displacement of [N-methyl-3H]GW0438 from human biotinylated LXRbeta ligand binding domainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28052FNPubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Genomics Institute of the Novartis Research Foundation (GNF)

Curated by ChEMBL
LigandPNGBDBM50538093(CHEMBL4645474)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged DYRK1A (1 to 763 residues) expressed in Sf21 cells using Ulight-glycogen synthase as substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WQ079VPubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Genomics Institute of the Novartis Research Foundation (GNF)

Curated by ChEMBL
LigandPNGBDBM50538084(CHEMBL4647659)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Inhibition of recombinant human GSK3beta (1 to 433 residues) expressed in mammalian expression system by Kinomescan methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WQ079VPubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Genomics Institute of the Novartis Research Foundation (GNF)

Curated by ChEMBL
LigandPNGBDBM50538094(CHEMBL4641631)copy SMILEScopy InChI
Affinity DataIC50: 17nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged DYRK1A (1 to 763 residues) expressed in Sf21 cells using Ulight-glycogen synthase as substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WQ079VPubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Inception Sciences

Curated by ChEMBL
LigandPNGBDBM50508126(CHEMBL4457564)copy SMILEScopy InChI
Affinity DataIC50: 17nMAssay Description:Antagonist activity at recombinant human PPARalpha assessed as inhibition of GW7647-induced receptor activation after overnight incubation by cell-ba...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8JVQPubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Genomics Institute of the Novartis Research Foundation (GNF)

Curated by ChEMBL
LigandPNGBDBM50538091(CHEMBL4640465)copy SMILEScopy InChI
Affinity DataIC50: 17nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged DYRK1A (1 to 763 residues) expressed in Sf21 cells using Ulight-glycogen synthase as substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WQ079VPubMed
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Inception Sciences

Curated by ChEMBL
LigandPNGBDBM50508159(CHEMBL4529735)copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:Antagonist activity at recombinant human PPARdelta assessed as inhibition of GW0742-induced receptor activation after overnight incubation by cell-ba...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8JVQPubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Inception Sciences

Curated by ChEMBL
LigandPNGBDBM50508137(CHEMBL4437146)copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:Antagonist activity at recombinant human PPARalpha assessed as inhibition of GW7647-induced receptor activation after overnight incubation by cell-ba...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8JVQPubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Inception Sciences

Curated by ChEMBL
LigandPNGBDBM50508153(CHEMBL4549922)copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:Antagonist activity at recombinant human PPARalpha assessed as inhibition of GW7647-induced receptor activation after overnight incubation by cell-ba...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8JVQPubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Inception Sciences

Curated by ChEMBL
LigandPNGBDBM50508144(CHEMBL4545223)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:Antagonist activity at recombinant human PPARalpha assessed as inhibition of GW7647-induced receptor activation after overnight incubation by cell-ba...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8JVQPubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Inception Sciences

Curated by ChEMBL
LigandPNGBDBM50508159(CHEMBL4529735)copy SMILEScopy InChI
Affinity DataIC50: 23nMAssay Description:Antagonist activity at recombinant human PPARalpha assessed as inhibition of GW7647-induced receptor activation after overnight incubation by cell-ba...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8JVQPubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
GlaxoSmithKline Research and Development

Curated by ChEMBL
LigandPNGBDBM50252939(2-[4-(Butyl{[3-chloro-4,5-bis(methyloxy)phenyl]met...)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Displacement of [N-methyl-3H]GW0438 from human biotinylated LXRbeta ligand binding domainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28052FNPubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
GlaxoSmithKline Research and Development

Curated by ChEMBL
LigandPNGBDBM50252850(2-{4-[Butyl(pyridin-4-ylmethyl)amino]phenyl}-1,1,1...)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Displacement of [N-methyl-3H]GW0438 from human biotinylated LXRbeta ligand binding domainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28052FNPubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Genomics Institute of the Novartis Research Foundation (GNF)

Curated by ChEMBL
LigandPNGBDBM50538096(CHEMBL4641672)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged DYRK1A (1 to 763 residues) expressed in Sf21 cells using Ulight-glycogen synthase as substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WQ079VPubMed
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Inception Sciences

Curated by ChEMBL
LigandPNGBDBM50508127(CHEMBL4449687)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Antagonist activity at recombinant human PPARdelta assessed as inhibition of GW0742-induced receptor activation after overnight incubation by cell-ba...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8JVQPubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
GlaxoSmithKline Research and Development

Curated by ChEMBL
LigandPNGBDBM19992(2-[3-[3-[[2-chloro-3-(trifluoromethyl)phenyl]methy...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Displacement of [N-methyl-3H]GW0438 from human biotinylated LXRbeta ligand binding domainMore data for this Ligand-Target Pair
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
GlaxoSmithKline Research and Development

Curated by ChEMBL
LigandPNGBDBM50252817(2-{4-[Butyl(pyridin-2-ylmethyl)amino]phenyl}-1,1,1...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Displacement of [N-methyl-3H]GW0438 from human biotinylated LXRbeta ligand binding domainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28052FNPubMed
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Inception Sciences

Curated by ChEMBL
LigandPNGBDBM50508145(CHEMBL4450146)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Antagonist activity at recombinant human PPARdelta assessed as inhibition of GW0742-induced receptor activation after overnight incubation by cell-ba...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8JVQPubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
GlaxoSmithKline Research and Development

Curated by ChEMBL
LigandPNGBDBM19993(CHEMBL62136 | N-[4-(1,1,1,3,3,3-hexafluoro-2-hydro...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Displacement of [N-methyl-3H]GW0438 from human biotinylated LXRbeta ligand binding domainMore data for this Ligand-Target Pair
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
GlaxoSmithKline Research and Development

Curated by ChEMBL
LigandPNGBDBM50252967(2-{4-[Butyl(3,5-dichloro-4-methoxybenzyl)amino]phe...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Displacement of [N-methyl-3H]GW0438 from human biotinylated LXRbeta ligand binding domainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28052FNPubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
GlaxoSmithKline Research and Development

Curated by ChEMBL
LigandPNGBDBM50252941(2-{4-[Butyl(3,5-dichlorobenzyl)amino]phenyl}-1,1,1...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Displacement of [N-methyl-3H]GW0438 from human biotinylated LXRbeta ligand binding domainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28052FNPubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
GlaxoSmithKline Research and Development

Curated by ChEMBL
LigandPNGBDBM50252852(3-[(Butyl{4-[2,2,2-trifluoro-1-hydroxy-1-(trifluor...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Displacement of [N-methyl-3H]GW0438 from human biotinylated LXRbeta ligand binding domainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28052FNPubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
GlaxoSmithKline Research and Development

Curated by ChEMBL
LigandPNGBDBM50252940(4-[(Butyl{4-[2,2,2-trifluoro-1-hydroxy-1-(trifluor...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Displacement of [N-methyl-3H]GW0438 from human biotinylated LXRbeta ligand binding domainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28052FNPubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Inception Sciences

Curated by ChEMBL
LigandPNGBDBM50508147(CHEMBL4530053)copy SMILEScopy InChI
Affinity DataIC50: 32nMAssay Description:Antagonist activity at recombinant human PPARalpha assessed as inhibition of GW7647-induced receptor activation after overnight incubation by cell-ba...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8JVQPubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Inception Sciences

Curated by ChEMBL
LigandPNGBDBM50508151(CHEMBL4449183)copy SMILEScopy InChI
Affinity DataIC50: 33nMAssay Description:Antagonist activity at recombinant human PPARalpha assessed as inhibition of GW7647-induced receptor activation after overnight incubation by cell-ba...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8JVQPubMed
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Inception Sciences

Curated by ChEMBL
LigandPNGBDBM50508126(CHEMBL4457564)copy SMILEScopy InChI
Affinity DataIC50: 34nMAssay Description:Antagonist activity at recombinant human PPARdelta assessed as inhibition of GW0742-induced receptor activation after overnight incubation by cell-ba...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8JVQPubMed
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Inception Sciences

Curated by ChEMBL
LigandPNGBDBM50508143(CHEMBL4443720)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Antagonist activity at recombinant human PPARdelta assessed as inhibition of GW0742-induced receptor activation after overnight incubation by cell-ba...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8JVQPubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Inception Sciences

Curated by ChEMBL
LigandPNGBDBM50013729(CHEMBL3264919)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Antagonist activity at human PPARalphaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8JVQPubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
GlaxoSmithKline Research and Development

Curated by ChEMBL
LigandPNGBDBM50252851(2-[(Butyl{4-[2,2,2-trifluoro-1-hydroxy-1-(trifluor...)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Displacement of [N-methyl-3H]GW0438 from human biotinylated LXRbeta ligand binding domainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28052FNPubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Genomics Institute of the Novartis Research Foundation (GNF)

Curated by ChEMBL
LigandPNGBDBM50538083(CHEMBL4638292)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Inhibition of recombinant human GSK3beta (1 to 433 residues) expressed in mammalian expression system by Kinomescan methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WQ079VPubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
GlaxoSmithKline Research and Development

Curated by ChEMBL
LigandPNGBDBM50252815(2-{4-[Benzyl(butyl)amino]phenyl}-1,1,1,3,3,3-hexaf...)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Displacement of [N-methyl-3H]GW0438 from human biotinylated LXRbeta ligand binding domainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28052FNPubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Genomics Institute of the Novartis Research Foundation (GNF)

Curated by ChEMBL
LigandPNGBDBM50538085(CHEMBL4634969)copy SMILEScopy InChI
Affinity DataIC50: 43nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged DYRK1A (1 to 763 residues) expressed in Sf21 cells using Ulight-glycogen synthase as substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WQ079VPubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Genomics Institute of the Novartis Research Foundation (GNF)

Curated by ChEMBL
LigandPNGBDBM50538097(CHEMBL4641839)copy SMILEScopy InChI
Affinity DataIC50: 43nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged DYRK1A (1 to 763 residues) expressed in Sf21 cells using Ulight-glycogen synthase as substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WQ079VPubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
GlaxoSmithKline Research and Development

Curated by ChEMBL
LigandPNGBDBM50252938(4-[(Butyl{4-[2,2,2-trifluoro-1-hydroxy-1-(trifluor...)copy SMILEScopy InChI
Affinity DataIC50: 45nMAssay Description:Displacement of [N-methyl-3H]GW0438 from human biotinylated LXRbeta ligand binding domainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28052FNPubMed
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Inception Sciences

Curated by ChEMBL
LigandPNGBDBM50508155(CHEMBL4592038)copy SMILEScopy InChI
Affinity DataIC50: 47nMAssay Description:Antagonist activity at recombinant human PPARdelta assessed as inhibition of GW0742-induced receptor activation after overnight incubation by cell-ba...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8JVQPubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
GlaxoSmithKline Research and Development

Curated by ChEMBL
LigandPNGBDBM50252908(4-[(Butyl{4-[2,2,2-trifluoro-1-hydroxy-1-(trifluor...)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Displacement of [N-methyl-3H]GW0438 from human biotinylated LXRbeta ligand binding domainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28052FNPubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Inception Sciences

Curated by ChEMBL
LigandPNGBDBM50508125(CHEMBL4533138)copy SMILEScopy InChI
Affinity DataIC50: 51nMAssay Description:Antagonist activity at recombinant human PPARalpha assessed as inhibition of GW7647-induced receptor activation after overnight incubation by cell-ba...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8JVQPubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Inception Sciences

Curated by ChEMBL
LigandPNGBDBM50508128(CHEMBL4539262)copy SMILEScopy InChI
Affinity DataIC50: 55nMAssay Description:Antagonist activity at recombinant human PPARalpha assessed as inhibition of GW7647-induced receptor activation after overnight incubation by cell-ba...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8JVQPubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Inception Sciences

Curated by ChEMBL
LigandPNGBDBM50508132(CHEMBL4546054)copy SMILEScopy InChI
Affinity DataIC50: 56nMAssay Description:Antagonist activity at recombinant human PPARalpha assessed as inhibition of GW7647-induced receptor activation after overnight incubation by cell-ba...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8JVQPubMed
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Inception Sciences

Curated by ChEMBL
LigandPNGBDBM50508141(CHEMBL4447577)copy SMILEScopy InChI
Affinity DataIC50: 61nMAssay Description:Antagonist activity at recombinant human PPARdelta assessed as inhibition of GW0742-induced receptor activation after overnight incubation by cell-ba...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8JVQPubMed
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Inception Sciences

Curated by ChEMBL
LigandPNGBDBM50508146(CHEMBL4587456)copy SMILEScopy InChI
Affinity DataIC50: 66nMAssay Description:Antagonist activity at recombinant human PPARdelta assessed as inhibition of GW0742-induced receptor activation after overnight incubation by cell-ba...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8JVQPubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Inception Sciences

Curated by ChEMBL
LigandPNGBDBM50508146(CHEMBL4587456)copy SMILEScopy InChI
Affinity DataIC50: 66nMAssay Description:Antagonist activity at recombinant human PPARalpha assessed as inhibition of GW7647-induced receptor activation after overnight incubation by cell-ba...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8JVQPubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Genomics Institute of the Novartis Research Foundation (GNF)

Curated by ChEMBL
LigandPNGBDBM50375654(CHEMBL99203 | US11633415, Compound 5-iodotubercidi...)copy SMILEScopy InChI
Affinity DataIC50: 71nMAssay Description:Inhibition of DYRK1A (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WQ079VPubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
GlaxoSmithKline Research and Development

Curated by ChEMBL
LigandPNGBDBM19993(CHEMBL62136 | N-[4-(1,1,1,3,3,3-hexafluoro-2-hydro...)copy SMILEScopy InChI
Affinity DataIC50: 75nMAssay Description:Displacement of [N-methyl-3H]GW0438 from human biotinylated LXRalpha ligand binding domainMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Inception Sciences

Curated by ChEMBL
LigandPNGBDBM50508150(CHEMBL4547480)copy SMILEScopy InChI
Affinity DataIC50: 79nMAssay Description:Antagonist activity at recombinant human PPARdelta assessed as inhibition of GW0742-induced receptor activation after overnight incubation by cell-ba...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8JVQPubMed
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