Compile Data Set for Download or QSAR
Found 192 with Last Name = 'hirschfeld' and Initial = 'd'
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50312996((R,S)-3-(5-chloro-1-methyl-1H-indol-3-yl)-4-(3-(2,...)copy SMILEScopy InChI
Affinity DataIC50: 0.400nMAssay Description:Inhibition of human recombinant GSK3-beta assessed as [gamma33]ATP transfer to biotinylated CREB-peptide substrate after 1 hr by scintillation counti...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5HNSPubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50313013(CHEMBL1080901 | CT-98024 | N2-(2-(4-(2,4-dichlorop...)copy SMILEScopy InChI
Affinity DataIC50: 0.560nMAssay Description:Inhibition of human recombinant GSK3-beta assessed as [gamma33]ATP transfer to biotinylated CREB-peptide substrate after 1 hr by scintillation counti...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5HNSPubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50312997(3-(3-(3-hydroxypropylamino)phenyl)-4-(1-methyl-1H-...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of human recombinant GSK3-beta assessed as [gamma33]ATP transfer to biotinylated CREB-peptide substrate after 1 hr by scintillation counti...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5HNSPubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50312998((R,S)-3-(3-(2,3-dihydroxypropyl)phenyl)-4-(5-fluor...)copy SMILEScopy InChI
Affinity DataIC50: 1.80nMAssay Description:Inhibition of human recombinant GSK3-beta assessed as [gamma33]ATP transfer to biotinylated CREB-peptide substrate after 1 hr by scintillation counti...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5HNSPubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM2647((Phenylindolyl)maleimide deriv. 69 | 3-(3-aminophe...)copy SMILEScopy InChI
Affinity DataIC50: 1.80nMAssay Description:Inhibition of human recombinant GSK3-beta assessed as [gamma33]ATP transfer to biotinylated CREB-peptide substrate after 1 hr by scintillation counti...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5HNSPubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50313010(3-(2,4-dimethoxyphenyl)-4-(1-methyl-1H-indol-3-yl)...)copy SMILEScopy InChI
Affinity DataIC50: 2.40nMAssay Description:Inhibition of human recombinant GSK3-beta assessed as [gamma33]ATP transfer to biotinylated CREB-peptide substrate after 1 hr by scintillation counti...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5HNSPubMed
TargetGag-Pol polyprotein [588-1027](Human immunodeficiency virus type 1 group M subtyp...)
Roche Palo Alto LLC

LigandPNGBDBM27614(3-(6-bromo-2-fluoro-3-{1H-pyrazolo[3,4-c]pyridazin...)copy SMILEScopy InChI
Affinity DataIC50: 3nM EC50:  1nMpH: 8.0 T: 2°CAssay Description:IC50s were obtained from the inhibition of the RNA-dependent DNA polymerase activity of the HIV-1 reverse transcriptase enzyme using a primer extensi...More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [588-1027,K691N,Y769C]/[588-1147,K691N,Y769C](Human immunodeficiency virus type 1)
Roche Palo Alto LLC

LigandPNGBDBM27614(3-(6-bromo-2-fluoro-3-{1H-pyrazolo[3,4-c]pyridazin...)copy SMILEScopy InChI
Affinity DataIC50: 3nM EC50:  4nMpH: 8.0 T: 2°CAssay Description:IC50s were obtained from the inhibition of the RNA-dependent DNA polymerase activity of the HIV-1 reverse transcriptase enzyme using a primer extensi...More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [588-1027](Human immunodeficiency virus type 1 group M subtyp...)
Roche Palo Alto LLC

LigandPNGBDBM27615(3-(6-bromo-2-fluoro-3-{1H-pyrazolo[3,4-b]pyrazin-3...)copy SMILEScopy InChI
Affinity DataIC50: 3nM EC50: >25nMpH: 8.0 T: 2°CAssay Description:IC50s were obtained from the inhibition of the RNA-dependent DNA polymerase activity of the HIV-1 reverse transcriptase enzyme using a primer extensi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TQ5ZV0PubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50313000((R)-3-(3-(2,3-dihydroxypropyl)phenyl)-4-(1-methyl-...)copy SMILEScopy InChI
Affinity DataIC50: 3.20nMAssay Description:Inhibition of human recombinant GSK3-beta assessed as [gamma33]ATP transfer to biotinylated CREB-peptide substrate after 1 hr by scintillation counti...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5HNSPubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM2651((Phenylindolyl)maleimide deriv. 73 | 3-(2-chloroph...)copy SMILEScopy InChI
Affinity DataIC50: 3.60nMAssay Description:Inhibition of human recombinant GSK3-beta assessed as [gamma33]ATP transfer to biotinylated CREB-peptide substrate after 1 hr by scintillation counti...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5HNSPubMed
TargetGag-Pol polyprotein [588-1027](Human immunodeficiency virus type 1 group M subtyp...)
Roche Palo Alto LLC

LigandPNGBDBM27613(3-(6-bromo-2-fluoro-3-{1H-pyrazolo[3,4-c]pyridin-3...)copy SMILEScopy InChI
Affinity DataIC50: 5nM EC50:  2nMpH: 8.0 T: 2°CAssay Description:IC50s were obtained from the inhibition of the RNA-dependent DNA polymerase activity of the HIV-1 reverse transcriptase enzyme using a primer extensi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TQ5ZV0PubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50313003(3-(5-chloro-1-methyl-1H-indol-3-yl)-4-(3-methoxyph...)copy SMILEScopy InChI
Affinity DataIC50: 6.40nMAssay Description:Inhibition of human recombinant GSK3-beta assessed as [gamma33]ATP transfer to biotinylated CREB-peptide substrate after 1 hr by scintillation counti...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5HNSPubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50313009(3-(3,4-dimethoxyphenyl)-4-(1-methyl-1H-indol-3-yl)...)copy SMILEScopy InChI
Affinity DataIC50: 6.60nMAssay Description:Inhibition of human recombinant GSK3-beta assessed as [gamma33]ATP transfer to biotinylated CREB-peptide substrate after 1 hr by scintillation counti...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5HNSPubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50313011(31-(dimethylamino)-5,11,15,25,30-pentaazaheptacycl...)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Inhibition of human recombinant GSK3-beta assessed as [gamma33]ATP transfer to biotinylated CREB-peptide substrate after 1 hr by scintillation counti...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5HNSPubMed
TargetGag-Pol polyprotein [588-1027](Human immunodeficiency virus type 1 group M subtyp...)
Roche Palo Alto LLC

LigandPNGBDBM27611(3-[6-bromo-2-fluoro-3-({6-methyl-7-oxo-1H,6H,7H-py...)copy SMILEScopy InChI
Affinity DataIC50: 8nM EC50:  4nMpH: 8.0 T: 2°CAssay Description:IC50s were obtained from the inhibition of the RNA-dependent DNA polymerase activity of the HIV-1 reverse transcriptase enzyme using a primer extensi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TQ5ZV0PubMed
TargetGag-Pol polyprotein [588-1027](Human immunodeficiency virus type 1 group M subtyp...)
Roche Palo Alto LLC

LigandPNGBDBM27612(3-(6-bromo-2-fluoro-3-{1H-pyrazolo[3,4-b]pyridin-3...)copy SMILEScopy InChI
Affinity DataIC50: 8nM EC50:  1nMpH: 8.0 T: 2°CAssay Description:IC50s were obtained from the inhibition of the RNA-dependent DNA polymerase activity of the HIV-1 reverse transcriptase enzyme using a primer extensi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TQ5ZV0PubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50312999((S)-3-(3-(2,3-dihydroxypropyl)phenyl)-4-(1-methyl-...)copy SMILEScopy InChI
Affinity DataIC50: 8.20nMAssay Description:Inhibition of human recombinant GSK3-beta assessed as [gamma33]ATP transfer to biotinylated CREB-peptide substrate after 1 hr by scintillation counti...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5HNSPubMed
TargetGag-Pol polyprotein [588-1027,K691N,Y769C]/[588-1147,K691N,Y769C](Human immunodeficiency virus type 1)
Roche Palo Alto LLC

LigandPNGBDBM27613(3-(6-bromo-2-fluoro-3-{1H-pyrazolo[3,4-c]pyridin-3...)copy SMILEScopy InChI
Affinity DataIC50: 9nM EC50:  18nMpH: 8.0 T: 2°CAssay Description:IC50s were obtained from the inhibition of the RNA-dependent DNA polymerase activity of the HIV-1 reverse transcriptase enzyme using a primer extensi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TQ5ZV0PubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50313012(10-(4-(1-methyl-1H-indol-3-yl)-2,5-dioxo-2,5-dihyd...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of human recombinant GSK3-beta assessed as [gamma33]ATP transfer to biotinylated CREB-peptide substrate after 1 hr by scintillation counti...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5HNSPubMed
TargetGag-Pol polyprotein [588-1027,K691N,Y769C]/[588-1147,K691N,Y769C](Human immunodeficiency virus type 1)
Roche Palo Alto LLC

LigandPNGBDBM27611(3-[6-bromo-2-fluoro-3-({6-methyl-7-oxo-1H,6H,7H-py...)copy SMILEScopy InChI
Affinity DataIC50: 12nM EC50:  97nMpH: 8.0 T: 2°CAssay Description:IC50s were obtained from the inhibition of the RNA-dependent DNA polymerase activity of the HIV-1 reverse transcriptase enzyme using a primer extensi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TQ5ZV0PubMed
TargetGag-Pol polyprotein [588-1027,K691N,Y769C]/[588-1147,K691N,Y769C](Human immunodeficiency virus type 1)
Roche Palo Alto LLC

LigandPNGBDBM27615(3-(6-bromo-2-fluoro-3-{1H-pyrazolo[3,4-b]pyrazin-3...)copy SMILEScopy InChI
Affinity DataIC50: 14nM EC50: >100nMpH: 8.0 T: 2°CAssay Description:IC50s were obtained from the inhibition of the RNA-dependent DNA polymerase activity of the HIV-1 reverse transcriptase enzyme using a primer extensi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TQ5ZV0PubMed
TargetReverse transcriptase protein(Human immunodeficiency virus 1)
Roche Palo Alto LLC

Curated by ChEMBL
LigandPNGBDBM50482300(CHEMBL1170386)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Inhibition of HIV1 reverse transcriptase K103N/Y181C double mutant by SPA heteropolymeric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z478KPubMed
TargetReverse transcriptase protein(Human immunodeficiency virus 1)
Roche Palo Alto LLC

Curated by ChEMBL
LigandPNGBDBM50482304(CHEMBL1170190)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Inhibition of HIV1 reverse transcriptase K103N/Y181C double mutant by SPA heteropolymeric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z478KPubMed
TargetGag-Pol polyprotein [588-1027,K691N,Y769C]/[588-1147,K691N,Y769C](Human immunodeficiency virus type 1)
Roche Palo Alto LLC

LigandPNGBDBM27609(3-{[4-bromo-3-(3-chloro-5-cyanophenoxy)-2-fluoroph...)copy SMILEScopy InChI
Affinity DataIC50: 15nM EC50:  53nMpH: 8.0 T: 2°CAssay Description:IC50s were obtained from the inhibition of the RNA-dependent DNA polymerase activity of the HIV-1 reverse transcriptase enzyme using a primer extensi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TQ5ZV0PubMed
TargetReverse transcriptase protein(Human immunodeficiency virus 1)
Roche Palo Alto LLC

Curated by ChEMBL
LigandPNGBDBM50482308(CHEMBL1169643)copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:Inhibition of HIV1 reverse transcriptase K103N/Y181C double mutant by SPA heteropolymeric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z478KPubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
Roche Palo Alto LLC

Curated by ChEMBL
LigandPNGBDBM50482304(CHEMBL1170190)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:Inhibition of wild type HIV1 reverse transcriptase by SPA heteropolymeric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z478KPubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50282633((S)-3-(8-((dimethylamino)methyl)-6,7,8,9-tetrahydr...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of human recombinant GSK3-beta assessed as [gamma33]ATP transfer to biotinylated CREB-peptide substrate after 1 hr by scintillation counti...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5HNSPubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
Roche Palo Alto LLC

Curated by ChEMBL
LigandPNGBDBM50482308(CHEMBL1169643)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:Inhibition of wild type HIV1 reverse transcriptase by SPA heteropolymeric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z478KPubMed
TargetReverse transcriptase protein(Human immunodeficiency virus 1)
Roche Palo Alto LLC

Curated by ChEMBL
LigandPNGBDBM50482298(CHEMBL1171403)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:Inhibition of HIV1 reverse transcriptase K103N/Y181C double mutant by SPA heteropolymeric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z478KPubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
Roche Palo Alto LLC

Curated by ChEMBL
LigandPNGBDBM50482299(CHEMBL1170387)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:Inhibition of wild type HIV1 reverse transcriptase by SPA heteropolymeric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z478KPubMed
TargetGag-Pol polyprotein [588-1027,K691N,Y769C]/[588-1147,K691N,Y769C](Human immunodeficiency virus type 1)
Roche Palo Alto LLC

LigandPNGBDBM27610(3-{3-[(7-amino-1H-indazol-3-yl)methyl]-6-bromo-2-f...)copy SMILEScopy InChI
Affinity DataIC50: 22nM EC50:  84nMpH: 8.0 T: 2°CAssay Description:IC50s were obtained from the inhibition of the RNA-dependent DNA polymerase activity of the HIV-1 reverse transcriptase enzyme using a primer extensi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TQ5ZV0PubMed
TargetProtein kinase C alpha type(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50282633((S)-3-(8-((dimethylamino)methyl)-6,7,8,9-tetrahydr...)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:Inhibition of PKCalphaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5HNSPubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50313008(3-(2,5-dimethoxyphenyl)-4-(1-methyl-1H-indol-3-yl)...)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:Inhibition of human recombinant GSK3-beta assessed as [gamma33]ATP transfer to biotinylated CREB-peptide substrate after 1 hr by scintillation counti...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5HNSPubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM2604((Arylindolyl)maleimide deriv. 26 | 3-(1-methyl-1H-...)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:Inhibition of human recombinant GSK3-beta assessed as [gamma33]ATP transfer to biotinylated CREB-peptide substrate after 1 hr by scintillation counti...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5HNSPubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
Roche Palo Alto LLC

Curated by ChEMBL
LigandPNGBDBM50482301(CHEMBL1170591)copy SMILEScopy InChI
Affinity DataIC50: 23nMAssay Description:Inhibition of wild type HIV1 reverse transcriptase by SPA heteropolymeric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z478KPubMed
TargetGag-Pol polyprotein [588-1027](Human immunodeficiency virus type 1 group M subtyp...)
Roche Palo Alto LLC

LigandPNGBDBM27610(3-{3-[(7-amino-1H-indazol-3-yl)methyl]-6-bromo-2-f...)copy SMILEScopy InChI
Affinity DataIC50: 24nM EC50:  8nMpH: 8.0 T: 2°CAssay Description:IC50s were obtained from the inhibition of the RNA-dependent DNA polymerase activity of the HIV-1 reverse transcriptase enzyme using a primer extensi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TQ5ZV0PubMed
TargetGag-Pol polyprotein [588-1027](Human immunodeficiency virus type 1 group M subtyp...)
Roche Palo Alto LLC

LigandPNGBDBM27609(3-{[4-bromo-3-(3-chloro-5-cyanophenoxy)-2-fluoroph...)copy SMILEScopy InChI
Affinity DataIC50: 24nM EC50:  5nMpH: 8.0 T: 2°CAssay Description:IC50s were obtained from the inhibition of the RNA-dependent DNA polymerase activity of the HIV-1 reverse transcriptase enzyme using a primer extensi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TQ5ZV0PubMed
TargetReverse transcriptase protein(Human immunodeficiency virus 1)
Roche Palo Alto LLC

Curated by ChEMBL
LigandPNGBDBM50482310(CHEMBL1170006)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Inhibition of HIV1 reverse transcriptase K103N/Y181C double mutant by SPA heteropolymeric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z478KPubMed
TargetReverse transcriptase protein(Human immunodeficiency virus 1)
Roche Palo Alto LLC

Curated by ChEMBL
LigandPNGBDBM50482301(CHEMBL1170591)copy SMILEScopy InChI
Affinity DataIC50: 27nMAssay Description:Inhibition of HIV1 reverse transcriptase K103N/Y181C double mutant by SPA heteropolymeric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z478KPubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
Roche Palo Alto LLC

Curated by ChEMBL
LigandPNGBDBM50482300(CHEMBL1170386)copy SMILEScopy InChI
Affinity DataIC50: 28nMAssay Description:Inhibition of wild type HIV1 reverse transcriptase by SPA heteropolymeric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z478KPubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
Roche Palo Alto LLC

Curated by ChEMBL
LigandPNGBDBM50482300(CHEMBL1170386)copy SMILEScopy InChI
Affinity DataIC50: 28nMAssay Description:Inhibition of HIV1 reverse transcriptase Y188L mutant by SPA heteropolymeric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z478KPubMed
TargetReverse transcriptase protein(Human immunodeficiency virus 1)
Roche Palo Alto LLC

Curated by ChEMBL
LigandPNGBDBM50482313(CHEMBL1170005)copy SMILEScopy InChI
Affinity DataIC50: 28nMAssay Description:Inhibition of HIV1 reverse transcriptase K103N/Y181C double mutant by SPA heteropolymeric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z478KPubMed
TargetReverse transcriptase protein(Human immunodeficiency virus 1)
Roche Palo Alto LLC

Curated by ChEMBL
LigandPNGBDBM50482306(CHEMBL1172334)copy SMILEScopy InChI
Affinity DataIC50: 28nMAssay Description:Inhibition of HIV1 reverse transcriptase K103N/Y181C double mutant by SPA heteropolymeric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z478KPubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
Roche Palo Alto LLC

Curated by ChEMBL
LigandPNGBDBM50482302(CHEMBL1170378)copy SMILEScopy InChI
Affinity DataIC50: 29nMAssay Description:Inhibition of wild type HIV1 reverse transcriptase by SPA heteropolymeric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z478KPubMed
TargetReverse transcriptase protein(Human immunodeficiency virus 1)
Roche Palo Alto LLC

Curated by ChEMBL
LigandPNGBDBM50482299(CHEMBL1170387)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibition of HIV1 reverse transcriptase K103N/Y181C double mutant by SPA heteropolymeric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z478KPubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50313004(3-(6-fluoro-1-methyl-1H-indol-3-yl)-4-(3-methoxyph...)copy SMILEScopy InChI
Affinity DataIC50: 31nMAssay Description:Inhibition of human recombinant GSK3-beta assessed as [gamma33]ATP transfer to biotinylated CREB-peptide substrate after 1 hr by scintillation counti...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5HNSPubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
Roche Palo Alto LLC

Curated by ChEMBL
LigandPNGBDBM50482306(CHEMBL1172334)copy SMILEScopy InChI
Affinity DataIC50: 32nMAssay Description:Inhibition of wild type HIV1 reverse transcriptase by SPA heteropolymeric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z478KPubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
Roche Palo Alto LLC

Curated by ChEMBL
LigandPNGBDBM50482307(CHEMBL1169811)copy SMILEScopy InChI
Affinity DataIC50: 34nMAssay Description:Inhibition of wild type HIV1 reverse transcriptase by SPA heteropolymeric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z478KPubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50313002(3-(1,6-dimethyl-1H-indol-3-yl)-4-(3-methoxyphenyl)...)copy SMILEScopy InChI
Affinity DataIC50: 35nMAssay Description:Inhibition of human recombinant GSK3-beta assessed as [gamma33]ATP transfer to biotinylated CREB-peptide substrate after 1 hr by scintillation counti...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5HNSPubMed
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