Compile Data Set for Download or QSAR
Found 20 with Last Name = 'billedeau' and Initial = 'jr'
TargetGag-Pol polyprotein [588-1027](Human immunodeficiency virus type 1 group M subtyp...)
Roche Palo Alto LLC

LigandPNGBDBM27614(3-(6-bromo-2-fluoro-3-{1H-pyrazolo[3,4-c]pyridazin...)copy SMILEScopy InChI
Affinity DataIC50: 3nM EC50:  1nMpH: 8.0 T: 2°CAssay Description:IC50s were obtained from the inhibition of the RNA-dependent DNA polymerase activity of the HIV-1 reverse transcriptase enzyme using a primer extensi...More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [588-1027](Human immunodeficiency virus type 1 group M subtyp...)
Roche Palo Alto LLC

LigandPNGBDBM27615(3-(6-bromo-2-fluoro-3-{1H-pyrazolo[3,4-b]pyrazin-3...)copy SMILEScopy InChI
Affinity DataIC50: 3nM EC50: >25nMpH: 8.0 T: 2°CAssay Description:IC50s were obtained from the inhibition of the RNA-dependent DNA polymerase activity of the HIV-1 reverse transcriptase enzyme using a primer extensi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TQ5ZV0PubMed
TargetGag-Pol polyprotein [588-1027,K691N,Y769C]/[588-1147,K691N,Y769C](Human immunodeficiency virus type 1)
Roche Palo Alto LLC

LigandPNGBDBM27614(3-(6-bromo-2-fluoro-3-{1H-pyrazolo[3,4-c]pyridazin...)copy SMILEScopy InChI
Affinity DataIC50: 3nM EC50:  4nMpH: 8.0 T: 2°CAssay Description:IC50s were obtained from the inhibition of the RNA-dependent DNA polymerase activity of the HIV-1 reverse transcriptase enzyme using a primer extensi...More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [588-1027](Human immunodeficiency virus type 1 group M subtyp...)
Roche Palo Alto LLC

LigandPNGBDBM27613(3-(6-bromo-2-fluoro-3-{1H-pyrazolo[3,4-c]pyridin-3...)copy SMILEScopy InChI
Affinity DataIC50: 5nM EC50:  2nMpH: 8.0 T: 2°CAssay Description:IC50s were obtained from the inhibition of the RNA-dependent DNA polymerase activity of the HIV-1 reverse transcriptase enzyme using a primer extensi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TQ5ZV0PubMed
TargetGag-Pol polyprotein [588-1027](Human immunodeficiency virus type 1 group M subtyp...)
Roche Palo Alto LLC

LigandPNGBDBM27612(3-(6-bromo-2-fluoro-3-{1H-pyrazolo[3,4-b]pyridin-3...)copy SMILEScopy InChI
Affinity DataIC50: 8nM EC50:  1nMpH: 8.0 T: 2°CAssay Description:IC50s were obtained from the inhibition of the RNA-dependent DNA polymerase activity of the HIV-1 reverse transcriptase enzyme using a primer extensi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TQ5ZV0PubMed
TargetGag-Pol polyprotein [588-1027](Human immunodeficiency virus type 1 group M subtyp...)
Roche Palo Alto LLC

LigandPNGBDBM27611(3-[6-bromo-2-fluoro-3-({6-methyl-7-oxo-1H,6H,7H-py...)copy SMILEScopy InChI
Affinity DataIC50: 8nM EC50:  4nMpH: 8.0 T: 2°CAssay Description:IC50s were obtained from the inhibition of the RNA-dependent DNA polymerase activity of the HIV-1 reverse transcriptase enzyme using a primer extensi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TQ5ZV0PubMed
TargetGag-Pol polyprotein [588-1027,K691N,Y769C]/[588-1147,K691N,Y769C](Human immunodeficiency virus type 1)
Roche Palo Alto LLC

LigandPNGBDBM27613(3-(6-bromo-2-fluoro-3-{1H-pyrazolo[3,4-c]pyridin-3...)copy SMILEScopy InChI
Affinity DataIC50: 9nM EC50:  18nMpH: 8.0 T: 2°CAssay Description:IC50s were obtained from the inhibition of the RNA-dependent DNA polymerase activity of the HIV-1 reverse transcriptase enzyme using a primer extensi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TQ5ZV0PubMed
TargetGag-Pol polyprotein [588-1027,K691N,Y769C]/[588-1147,K691N,Y769C](Human immunodeficiency virus type 1)
Roche Palo Alto LLC

LigandPNGBDBM27611(3-[6-bromo-2-fluoro-3-({6-methyl-7-oxo-1H,6H,7H-py...)copy SMILEScopy InChI
Affinity DataIC50: 12nM EC50:  97nMpH: 8.0 T: 2°CAssay Description:IC50s were obtained from the inhibition of the RNA-dependent DNA polymerase activity of the HIV-1 reverse transcriptase enzyme using a primer extensi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TQ5ZV0PubMed
TargetGag-Pol polyprotein [588-1027,K691N,Y769C]/[588-1147,K691N,Y769C](Human immunodeficiency virus type 1)
Roche Palo Alto LLC

LigandPNGBDBM27615(3-(6-bromo-2-fluoro-3-{1H-pyrazolo[3,4-b]pyrazin-3...)copy SMILEScopy InChI
Affinity DataIC50: 14nM EC50: >100nMpH: 8.0 T: 2°CAssay Description:IC50s were obtained from the inhibition of the RNA-dependent DNA polymerase activity of the HIV-1 reverse transcriptase enzyme using a primer extensi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TQ5ZV0PubMed
TargetGag-Pol polyprotein [588-1027,K691N,Y769C]/[588-1147,K691N,Y769C](Human immunodeficiency virus type 1)
Roche Palo Alto LLC

LigandPNGBDBM27609(3-{[4-bromo-3-(3-chloro-5-cyanophenoxy)-2-fluoroph...)copy SMILEScopy InChI
Affinity DataIC50: 15nM EC50:  53nMpH: 8.0 T: 2°CAssay Description:IC50s were obtained from the inhibition of the RNA-dependent DNA polymerase activity of the HIV-1 reverse transcriptase enzyme using a primer extensi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TQ5ZV0PubMed
TargetGag-Pol polyprotein [588-1027,K691N,Y769C]/[588-1147,K691N,Y769C](Human immunodeficiency virus type 1)
Roche Palo Alto LLC

LigandPNGBDBM27610(3-{3-[(7-amino-1H-indazol-3-yl)methyl]-6-bromo-2-f...)copy SMILEScopy InChI
Affinity DataIC50: 22nM EC50:  84nMpH: 8.0 T: 2°CAssay Description:IC50s were obtained from the inhibition of the RNA-dependent DNA polymerase activity of the HIV-1 reverse transcriptase enzyme using a primer extensi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TQ5ZV0PubMed
TargetGag-Pol polyprotein [588-1027](Human immunodeficiency virus type 1 group M subtyp...)
Roche Palo Alto LLC

LigandPNGBDBM27610(3-{3-[(7-amino-1H-indazol-3-yl)methyl]-6-bromo-2-f...)copy SMILEScopy InChI
Affinity DataIC50: 24nM EC50:  8nMpH: 8.0 T: 2°CAssay Description:IC50s were obtained from the inhibition of the RNA-dependent DNA polymerase activity of the HIV-1 reverse transcriptase enzyme using a primer extensi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TQ5ZV0PubMed
TargetGag-Pol polyprotein [588-1027](Human immunodeficiency virus type 1 group M subtyp...)
Roche Palo Alto LLC

LigandPNGBDBM27609(3-{[4-bromo-3-(3-chloro-5-cyanophenoxy)-2-fluoroph...)copy SMILEScopy InChI
Affinity DataIC50: 24nM EC50:  5nMpH: 8.0 T: 2°CAssay Description:IC50s were obtained from the inhibition of the RNA-dependent DNA polymerase activity of the HIV-1 reverse transcriptase enzyme using a primer extensi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TQ5ZV0PubMed
TargetGag-Pol polyprotein [588-1027,K691N,Y769C]/[588-1147,K691N,Y769C](Human immunodeficiency virus type 1)
Roche Palo Alto LLC

LigandPNGBDBM27617(5-(6-bromo-2-fluoro-3-{1H-pyrazolo[3,4-c]pyridazin...)copy SMILEScopy InChI
Affinity DataEC50:  3nMpH: 8.0 T: 2°CAssay Description:IC50s were obtained from the inhibition of the RNA-dependent DNA polymerase activity of the HIV-1 reverse transcriptase enzyme using a primer extensi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TQ5ZV0PubMed
TargetGag-Pol polyprotein [588-1027,K691N,Y769C]/[588-1147,K691N,Y769C](Human immunodeficiency virus type 1)
Roche Palo Alto LLC

LigandPNGBDBM27616(3-chloro-5-(6-chloro-2-fluoro-3-{1H-pyrazolo[3,4-c...)copy SMILEScopy InChI
Affinity DataEC50:  5nMpH: 8.0 T: 2°CAssay Description:IC50s were obtained from the inhibition of the RNA-dependent DNA polymerase activity of the HIV-1 reverse transcriptase enzyme using a primer extensi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TQ5ZV0PubMed
TargetGag-Pol polyprotein [588-1027,K691N,Y769C]/[588-1147,K691N,Y769C](Human immunodeficiency virus type 1)
Roche Palo Alto LLC

LigandPNGBDBM27612(3-(6-bromo-2-fluoro-3-{1H-pyrazolo[3,4-b]pyridin-3...)copy SMILEScopy InChI
Affinity DataEC50:  12nMpH: 8.0 T: 2°CAssay Description:IC50s were obtained from the inhibition of the RNA-dependent DNA polymerase activity of the HIV-1 reverse transcriptase enzyme using a primer extensi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TQ5ZV0PubMed
TargetGag-Pol polyprotein [588-1027,K691N,Y769C]/[588-1147,K691N,Y769C](Human immunodeficiency virus type 1)
Roche Palo Alto LLC

LigandPNGBDBM27618(3-(2-bromo-4-{1H-pyrazolo[3,4-c]pyridazin-3-ylmeth...)copy SMILEScopy InChI
Affinity DataEC50: >100nMpH: 8.0 T: 2°CAssay Description:IC50s were obtained from the inhibition of the RNA-dependent DNA polymerase activity of the HIV-1 reverse transcriptase enzyme using a primer extensi...More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [588-1027](Human immunodeficiency virus type 1 group M subtyp...)
Roche Palo Alto LLC

LigandPNGBDBM27617(5-(6-bromo-2-fluoro-3-{1H-pyrazolo[3,4-c]pyridazin...)copy SMILEScopy InChI
Affinity DataEC50:  1nMpH: 8.0 T: 2°CAssay Description:IC50s were obtained from the inhibition of the RNA-dependent DNA polymerase activity of the HIV-1 reverse transcriptase enzyme using a primer extensi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TQ5ZV0PubMed
TargetGag-Pol polyprotein [588-1027](Human immunodeficiency virus type 1 group M subtyp...)
Roche Palo Alto LLC

LigandPNGBDBM27616(3-chloro-5-(6-chloro-2-fluoro-3-{1H-pyrazolo[3,4-c...)copy SMILEScopy InChI
Affinity DataEC50:  1nMpH: 8.0 T: 2°CAssay Description:IC50s were obtained from the inhibition of the RNA-dependent DNA polymerase activity of the HIV-1 reverse transcriptase enzyme using a primer extensi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TQ5ZV0PubMed
TargetGag-Pol polyprotein [588-1027](Human immunodeficiency virus type 1 group M subtyp...)
Roche Palo Alto LLC

LigandPNGBDBM27618(3-(2-bromo-4-{1H-pyrazolo[3,4-c]pyridazin-3-ylmeth...)copy SMILEScopy InChI
Affinity DataEC50:  17nMpH: 8.0 T: 2°CAssay Description:IC50s were obtained from the inhibition of the RNA-dependent DNA polymerase activity of the HIV-1 reverse transcriptase enzyme using a primer extensi...More data for this Ligand-Target Pair