Compile Data Set for Download or QSAR
Found 36 with Last Name = 'seleem' and Initial = 'mn'
TargetCarbonic anhydrase 2(Homo sapiens (Human))TBA
LigandPNGBDBM50405890(CHEMBL4782535)copy SMILEScopy InChI
Affinity DataKi:  0.320nMAssay Description:Antihistaminic activity against Histamine H1 receptor was measured on isolated terminal part of guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails
TargetCarbonic anhydrase 2(Homo sapiens (Human))TBA
LigandPNGBDBM50405889(CHEMBL4741159)copy SMILEScopy InChI
Affinity DataKi:  8.10nMAssay Description:Antihistaminic activity against Histamine H1 receptor was measured on isolated terminal part of guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails
TargetCarbonic anhydrase 2(Homo sapiens (Human))TBA
LigandPNGBDBM10880(AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)copy SMILEScopy InChI
Affinity DataKi:  13nMAssay Description:Antihistaminic activity against Histamine H1 receptor was measured on isolated terminal part of guinea pig ileumMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 13(Homo sapiens (Human))TBA
LigandPNGBDBM10880(AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)copy SMILEScopy InChI
Affinity DataKi:  16nMAssay Description:Inhibition of human carbonic anhydrase 13 expressed in Escherichia coliBL21(DE3) pLysS incubated for 10 mins by phenol red dye based assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))TBA
LigandPNGBDBM50547697(CHEMBL4739913)copy SMILES
Affinity DataKi:  20nMAssay Description:Antihistaminic activity against Histamine H1 receptor was measured on isolated terminal part of guinea pig ileumMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetCarbonic anhydrase 2(Homo sapiens (Human))TBA
LigandPNGBDBM50405887(CHEMBL4750765)copy SMILEScopy InChI
Affinity DataKi:  25nMAssay Description:Antihistaminic activity against Histamine H1 receptor was measured on isolated terminal part of guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails
TargetCarbonic anhydrase 2(Homo sapiens (Human))TBA
LigandPNGBDBM16669(CHEMBL281376 | N-(5-sulfamoyl-1,3,4-thiadiazol-2-y...)copy SMILEScopy InChI
Affinity DataKi:  29nMAssay Description:Antihistaminic activity against Histamine H1 receptor was measured on isolated terminal part of guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails
TargetCarbonic anhydrase 2(Homo sapiens (Human))TBA
LigandPNGBDBM50405888(CHEMBL5280695)copy SMILEScopy InChI
Affinity DataKi:  38nMAssay Description:Antihistaminic activity against Histamine H1 receptor was measured on isolated terminal part of guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails
TargetCarbonic anhydrase 2(Homo sapiens (Human))TBA
LigandPNGBDBM50405885(CHEMBL4749585)copy SMILEScopy InChI
Affinity DataKi:  47nMAssay Description:Antihistaminic activity against Histamine H1 receptor was measured on isolated terminal part of guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails
TargetCarbonic anhydrase 2(Homo sapiens (Human))TBA
LigandPNGBDBM10868(1,3,4-Thiadiazole-2-sulfonamide, 6 | 1,3,4-thiadia...)copy SMILEScopy InChI
Affinity DataKi:  60nMAssay Description:Antihistaminic activity against Histamine H1 receptor was measured on isolated terminal part of guinea pig ileumMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))TBA
LigandPNGBDBM50405886(CHEMBL4753745)copy SMILEScopy InChI
Affinity DataKi:  78nMAssay Description:Antihistaminic activity against Histamine H1 receptor was measured on isolated terminal part of guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM25259(3-(decyloxy)-1-(2-hydrogen phosphonato-2-phosphono...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition of human FPPS using IPP and GPPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S75KV9PubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM25271(3-[(3,7-dimethyloctyl)oxy]-1-(2-hydrogen phosphona...)copy SMILEScopy InChI
Affinity DataIC50: 230nMAssay Description:Inhibition of human FPPS using IPP and GPPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S75KV9PubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM25271(3-[(3,7-dimethyloctyl)oxy]-1-(2-hydrogen phosphona...)copy SMILEScopy InChI
Affinity DataIC50: 230nMAssay Description:Inhibition of human FPPS using IPP and GPP as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S75KV9PubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM12578(2-(imidazol-1-yl)-1-hydroxyethylidene-1,1-bisphosp...)copy SMILEScopy InChI
Affinity DataIC50: 250nMAssay Description:Inhibition of human FPPS using IPP and GPPMore data for this Ligand-Target Pair
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM25259(3-(decyloxy)-1-(2-hydrogen phosphonato-2-phosphono...)copy SMILEScopy InChI
Affinity DataIC50: 280nMAssay Description:Inhibition of human GGPPSMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S75KV9PubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))TBA
LigandPNGBDBM5655(2-(2-chlorophenyl)-5,7-dihydroxy-8-[(3S,4R)-3-hydr...)copy SMILEScopy InChI
Affinity DataIC50: 400nMAssay Description:Inhibition of human CDK2 expressed in sf9 insect cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K64NP9PubMed
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM25263(bisphosphonate, 19 | {2-[3-(decyloxy)phenyl]-1-hyd...)copy SMILEScopy InChI
Affinity DataIC50: 590nMAssay Description:Inhibition of human GGPPSMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S75KV9PubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))TBA
LigandPNGBDBM50193100(CHEMBL3898028)copy SMILEScopy InChI
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of human CDK2 expressed in sf9 insect cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K64NP9PubMed
TargetUndecaprenyl-diphosphatase(Escherichia coli (strain K12))
Al-Azhar University

Curated by ChEMBL
LigandPNGBDBM50458054(Albac 50 | Baci-Rx | Baciferm 50 | Baciguent | Bac...)copy SMILEScopy InChI
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibition of Escherichia coli UPPP expressed in Escherichia coli C41(DE3) using FPP as substrate preincubated for 15 mins followed by substrate addi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RR21VDPubMed
TargetUndecaprenyl-diphosphatase(Escherichia coli (strain K12))
Al-Azhar University

Curated by ChEMBL
LigandPNGBDBM50458053(CHEMBL4214440)copy SMILEScopy InChI
Affinity DataIC50: 8.10E+3nMAssay Description:Inhibition of Escherichia coli UPPP expressed in Escherichia coli C41(DE3) using FPP as substrate preincubated for 15 mins followed by substrate addi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RR21VDPubMed
TargetInorganic pyrophosphatase(Mycobacterium tuberculosis)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50444854(CHEMBL3099405)copy SMILEScopy InChI
Affinity DataIC50: 3.33E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis PPase using inorganic pyrophosphate as substrate preincubated for 2 mins followed by substrate addition meas...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K35W4CPubMed
TargetDitrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)(Escherichia coli (strain K12))
Al-Azhar University

Curated by ChEMBL
LigandPNGBDBM50458053(CHEMBL4214440)copy SMILEScopy InChI
Affinity DataIC50: 3.80E+4nMAssay Description:Inhibition of Escherichia coli UPPS using IPP and FPP as substrate preincubated for 30 mins followed by substrate addition measured after 20 mins by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RR21VDPubMed
TargetInorganic pyrophosphatase(Mycobacterium tuberculosis)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50444850(CHEMBL3099412)copy SMILEScopy InChI
Affinity DataIC50: 3.83E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis PPase using inorganic pyrophosphate as substrate preincubated for 2 mins followed by substrate addition meas...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K35W4CPubMed
TargetInorganic pyrophosphatase(Mycobacterium tuberculosis)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50444855(CHEMBL3099425)copy SMILEScopy InChI
Affinity DataIC50: 5.32E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis PPase using inorganic pyrophosphate as substrate preincubated for 2 mins followed by substrate addition meas...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K35W4CPubMed
TargetInorganic pyrophosphatase(Mycobacterium tuberculosis)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50444852(CHEMBL3099409)copy SMILEScopy InChI
Affinity DataIC50: 5.74E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis PPase using inorganic pyrophosphate as substrate preincubated for 2 mins followed by substrate addition meas...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K35W4CPubMed
TargetInorganic pyrophosphatase(Mycobacterium tuberculosis)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50444858(CHEMBL3099415)copy SMILEScopy InChI
Affinity DataIC50: 6.32E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis PPase using inorganic pyrophosphate as substrate preincubated for 2 mins followed by substrate addition meas...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K35W4CPubMed
TargetDitrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)(Escherichia coli (strain K12))
Al-Azhar University

Curated by ChEMBL
LigandPNGBDBM25271(3-[(3,7-dimethyloctyl)oxy]-1-(2-hydrogen phosphona...)copy SMILEScopy InChI
Affinity DataIC50: 6.60E+4nMAssay Description:Inhibition of Escherichia coli UPPS in presence of IPP and FPPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S75KV9PubMed
TargetInorganic pyrophosphatase(Mycobacterium tuberculosis)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50444851(CHEMBL3099410)copy SMILEScopy InChI
Affinity DataIC50: 8.81E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis PPase using inorganic pyrophosphate as substrate preincubated for 2 mins followed by substrate addition meas...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K35W4CPubMed
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM12578(2-(imidazol-1-yl)-1-hydroxyethylidene-1,1-bisphosp...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human GGPPSMore data for this Ligand-Target Pair
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50537059(CHEMBL4543393)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human FPPS using IPP and GPP as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S75KV9PubMed
TargetInorganic pyrophosphatase(Mycobacterium tuberculosis)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50444856(CHEMBL3099424)copy SMILEScopy InChI
Affinity DataIC50: 1.02E+5nMAssay Description:Inhibition of Mycobacterium tuberculosis PPase using inorganic pyrophosphate as substrate preincubated for 2 mins followed by substrate addition meas...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K35W4CPubMed
TargetInorganic pyrophosphatase(Mycobacterium tuberculosis)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50444853(CHEMBL3099407)copy SMILEScopy InChI
Affinity DataIC50: 1.18E+5nMAssay Description:Inhibition of Mycobacterium tuberculosis PPase using inorganic pyrophosphate as substrate preincubated for 2 mins followed by substrate addition meas...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K35W4CPubMed
TargetInorganic pyrophosphatase(Mycobacterium tuberculosis)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50444859(CHEMBL3099427)copy SMILEScopy InChI
Affinity DataIC50: 1.48E+5nMAssay Description:Inhibition of Mycobacterium tuberculosis PPase using inorganic pyrophosphate as substrate preincubated for 2 mins followed by substrate addition meas...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K35W4CPubMed
TargetInorganic pyrophosphatase(Mycobacterium tuberculosis)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50444857(CHEMBL3099418)copy SMILEScopy InChI
Affinity DataIC50: 3.55E+5nMAssay Description:Inhibition of Mycobacterium tuberculosis PPase using inorganic pyrophosphate as substrate preincubated for 2 mins followed by substrate addition meas...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K35W4CPubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM25263(bisphosphonate, 19 | {2-[3-(decyloxy)phenyl]-1-hyd...)copy SMILEScopy InChI
Affinity DataIC50: 5.50E+5nMAssay Description:Inhibition of human FPPS using IPP and GPPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S75KV9PubMed