Compile Data Set for Download or QSAR
Found 6 Enz. Inhib. hit(s) with Target = 'Geranylgeranyl pyrophosphate synthase' and Ligand = 'BDBM25259'
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
National Institute of Immunology

Curated by ChEMBL
LigandPNGBDBM25259(3-(decyloxy)-1-(2-hydrogen phosphonato-2-phosphono...)copy SMILEScopy InChI
Affinity DataKi:  6.90E+3nMAssay Description:Inhibition of human GGPPSChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0GF9PubMed
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
National Institute of Immunology

Curated by ChEMBL
LigandPNGBDBM25259(3-(decyloxy)-1-(2-hydrogen phosphonato-2-phosphono...)copy SMILEScopy InChI
Affinity DataIC50: 280nMpH: 7.0 T: 2°CAssay Description:The inhibitory activity of each test compound was evaluated by monitoring the formation of [14C]GGPP from FPP, using [14C]IPP as the substrate. To co...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2028PVTPubMed
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
National Institute of Immunology

Curated by ChEMBL
LigandPNGBDBM25259(3-(decyloxy)-1-(2-hydrogen phosphonato-2-phosphono...)copy SMILEScopy InChI
Affinity DataIC50: 280nMAssay Description:Inhibition of human GGPPSMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S75KV9PubMed
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
National Institute of Immunology

Curated by ChEMBL
LigandPNGBDBM25259(3-(decyloxy)-1-(2-hydrogen phosphonato-2-phosphono...)copy SMILEScopy InChI
Affinity DataIC50: 280nMAssay Description:Inhibition of human recombinant GGPS using [14C]-IPP as substrate incubated for 15 mins prior to substrate addition measured after 20 mins by scintil...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67J6MPubMed
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
National Institute of Immunology

Curated by ChEMBL
LigandPNGBDBM25259(3-(decyloxy)-1-(2-hydrogen phosphonato-2-phosphono...)copy SMILEScopy InChI
Affinity DataIC50: 280nMAssay Description:Inhibition of human recombinant GGPPS using [14C]-IPP as substrate incubated for 15 mins prior to substrate addition measured after 20 mins by scinti...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29024V1PubMed
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
National Institute of Immunology

Curated by ChEMBL
LigandPNGBDBM25259(3-(decyloxy)-1-(2-hydrogen phosphonato-2-phosphono...)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+5nMAssay Description:Inhibition of human GGPPSChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0GF9PubMed