Compile Data Set for Download or QSAR
Found 110 with Last Name = 'guo' and Initial = 'rt'
TargetGeranylgeranyl pyrophosphate synthase BTS1(Saccharomyces cerevisiae (Yeast))
Institute of Biological Chemistry

Curated by ChEMBL
LigandPNGBDBM25297(1-(2-hydrogen phosphonato-2-hydroxy-2-phosphonoeth...)copy SMILEScopy InChI
Affinity DataKi:  10nMAssay Description:Binding affinity to Saccharomyces cerevisiae GGPPSMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2J2FPubMed
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
Institute of Biological Chemistry

Curated by ChEMBL
LigandPNGBDBM25266(BPH-628 | bisphosphonate, 21 | {1-hydroxy-2-[3-(4-...)copy SMILEScopy InChI
Affinity DataKi:  20nMAssay Description:Binding affinity to human GGPPSMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2J2FPubMed
TargetGeranylgeranyl pyrophosphate synthase BTS1(Saccharomyces cerevisiae (Yeast))
Institute of Biological Chemistry

Curated by ChEMBL
LigandPNGBDBM25266(BPH-628 | bisphosphonate, 21 | {1-hydroxy-2-[3-(4-...)copy SMILEScopy InChI
Affinity DataKi:  30nMAssay Description:Binding affinity to Saccharomyces cerevisiae GGPPSMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2J2FPubMed
TargetGeranylgeranyl pyrophosphate synthase BTS1(Saccharomyces cerevisiae (Yeast))
Institute of Biological Chemistry

Curated by ChEMBL
LigandPNGBDBM25279(BPH-608 | bisphosphonate, 31 | {1-hydroxy-2-[3-(3-...)copy SMILEScopy InChI
Affinity DataKi:  30nMAssay Description:Binding affinity to Saccharomyces cerevisiae GGPPSMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2J2FPubMed
TargetGeranylgeranyl pyrophosphate synthase BTS1(Saccharomyces cerevisiae (Yeast))
Institute of Biological Chemistry

Curated by ChEMBL
LigandPNGBDBM25289(bisphosphonate, 38 | {1-hydroxy-2-[3-(3-phenylphen...)copy SMILEScopy InChI
Affinity DataKi:  60nMAssay Description:Binding affinity to Saccharomyces cerevisiae GGPPSMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2J2FPubMed
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
Institute of Biological Chemistry

Curated by ChEMBL
LigandPNGBDBM25279(BPH-608 | bisphosphonate, 31 | {1-hydroxy-2-[3-(3-...)copy SMILEScopy InChI
Affinity DataKi:  60nMAssay Description:Binding affinity to human GGPPSMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2J2FPubMed
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
Institute of Biological Chemistry

Curated by ChEMBL
LigandPNGBDBM25284((1-hydroxy-2-{3-[3-(naphthalene-2-sulfonamido)phen...)copy SMILEScopy InChI
Affinity DataKi:  70nMAssay Description:Binding affinity to human GGPPSMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2J2FPubMed
TargetGeranylgeranyl pyrophosphate synthase BTS1(Saccharomyces cerevisiae (Yeast))
Institute of Biological Chemistry

Curated by ChEMBL
LigandPNGBDBM25284((1-hydroxy-2-{3-[3-(naphthalene-2-sulfonamido)phen...)copy SMILEScopy InChI
Affinity DataKi:  80nMAssay Description:Binding affinity to Saccharomyces cerevisiae GGPPSMore data for this Ligand-Target Pair
TargetGeranylgeranyl pyrophosphate synthase BTS1(Saccharomyces cerevisiae (Yeast))
Institute of Biological Chemistry

Curated by ChEMBL
LigandPNGBDBM25288(BPH-629 | [1-hydroxy-2-(3-{8-oxatricyclo[7.4.0.0^{...)copy SMILEScopy InChI
Affinity DataKi:  110nMAssay Description:Binding affinity to Saccharomyces cerevisiae GGPPSMore data for this Ligand-Target Pair
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
Institute of Biological Chemistry

Curated by ChEMBL
LigandPNGBDBM25289(bisphosphonate, 38 | {1-hydroxy-2-[3-(3-phenylphen...)copy SMILEScopy InChI
Affinity DataKi:  110nMAssay Description:Binding affinity to human GGPPSMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2J2FPubMed
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
Institute of Biological Chemistry

Curated by ChEMBL
LigandPNGBDBM25288(BPH-629 | [1-hydroxy-2-(3-{8-oxatricyclo[7.4.0.0^{...)copy SMILEScopy InChI
Affinity DataKi:  110nMAssay Description:Binding affinity to human GGPPSMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2J2FPubMed
TargetGeranylgeranyl pyrophosphate synthase BTS1(Saccharomyces cerevisiae (Yeast))
Institute of Biological Chemistry

Curated by ChEMBL
LigandPNGBDBM25308((1-hydroxy-2-{imidazo[1,2-a]pyridin-3-yl}-1-phosph...)copy SMILEScopy InChI
Affinity DataKi:  130nMAssay Description:Binding affinity to Saccharomyces cerevisiae GGPPSMore data for this Ligand-Target Pair
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
Institute of Biological Chemistry

Curated by ChEMBL
LigandPNGBDBM25297(1-(2-hydrogen phosphonato-2-hydroxy-2-phosphonoeth...)copy SMILEScopy InChI
Affinity DataKi:  230nMAssay Description:Binding affinity to human GGPPSMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2J2FPubMed
TargetGeranylgeranyl pyrophosphate synthase BTS1(Saccharomyces cerevisiae (Yeast))
Institute of Biological Chemistry

Curated by ChEMBL
LigandPNGBDBM12578(2-(imidazol-1-yl)-1-hydroxyethylidene-1,1-bisphosp...)copy SMILEScopy InChI
Affinity DataKi:  260nMAssay Description:Binding affinity to Saccharomyces cerevisiae GGPPSMore data for this Ligand-Target Pair
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
Institute of Biological Chemistry

Curated by ChEMBL
LigandPNGBDBM25308((1-hydroxy-2-{imidazo[1,2-a]pyridin-3-yl}-1-phosph...)copy SMILEScopy InChI
Affinity DataKi:  1.80E+3nMAssay Description:Binding affinity to human GGPPSMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2J2FPubMed
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
Institute of Biological Chemistry

Curated by ChEMBL
LigandPNGBDBM12578(2-(imidazol-1-yl)-1-hydroxyethylidene-1,1-bisphosp...)copy SMILEScopy InChI
Affinity DataKi:  2.70E+3nMAssay Description:Binding affinity to human GGPPSMore data for this Ligand-Target Pair
TargetGeranylgeranyl pyrophosphate synthase BTS1(Saccharomyces cerevisiae (Yeast))
Institute of Biological Chemistry

Curated by ChEMBL
LigandPNGBDBM25297(1-(2-hydrogen phosphonato-2-hydroxy-2-phosphonoeth...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibition of Saccharomyces cerevisiae GGPPSMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2J2FPubMed
TargetGeranylgeranyl pyrophosphate synthase BTS1(Saccharomyces cerevisiae (Yeast))
Institute of Biological Chemistry

Curated by ChEMBL
LigandPNGBDBM25266(BPH-628 | bisphosphonate, 21 | {1-hydroxy-2-[3-(4-...)copy SMILEScopy InChI
Affinity DataIC50: 70nMAssay Description:Inhibition of Saccharomyces cerevisiae GGPPSMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2J2FPubMed
TargetGeranylgeranyl pyrophosphate synthase BTS1(Saccharomyces cerevisiae (Yeast))
Institute of Biological Chemistry

Curated by ChEMBL
LigandPNGBDBM25279(BPH-608 | bisphosphonate, 31 | {1-hydroxy-2-[3-(3-...)copy SMILEScopy InChI
Affinity DataIC50: 70nMAssay Description:Inhibition of Saccharomyces cerevisiae GGPPSMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2J2FPubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM25259(3-(decyloxy)-1-(2-hydrogen phosphonato-2-phosphono...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition of human FPPS using IPP and GPPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S75KV9PubMed
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
Institute of Biological Chemistry

Curated by ChEMBL
LigandPNGBDBM25256(bisphosphonate, 9 | hydrogen [2-(dodecyldimethylph...)copy SMILEScopy InChI
Affinity DataIC50: 100nMpH: 7.0 T: 2°CAssay Description:The inhibitory activity of each test compound was evaluated by monitoring the formation of [14C]GGPP from FPP, using [14C]IPP as the substrate. To co...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2028PVTPubMed
TargetGeranylgeranyl pyrophosphate synthase BTS1(Saccharomyces cerevisiae (Yeast))
Institute of Biological Chemistry

Curated by ChEMBL
LigandPNGBDBM25289(bisphosphonate, 38 | {1-hydroxy-2-[3-(3-phenylphen...)copy SMILEScopy InChI
Affinity DataIC50: 140nMAssay Description:Inhibition of Saccharomyces cerevisiae GGPPSMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2J2FPubMed
TargetGeranylgeranyl pyrophosphate synthase BTS1(Saccharomyces cerevisiae (Yeast))
Institute of Biological Chemistry

Curated by ChEMBL
LigandPNGBDBM25284((1-hydroxy-2-{3-[3-(naphthalene-2-sulfonamido)phen...)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Inhibition of Saccharomyces cerevisiae GGPPSMore data for this Ligand-Target Pair
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM25271(3-[(3,7-dimethyloctyl)oxy]-1-(2-hydrogen phosphona...)copy SMILEScopy InChI
Affinity DataIC50: 230nMAssay Description:Inhibition of human FPPS using IPP and GPP as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S75KV9PubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM25271(3-[(3,7-dimethyloctyl)oxy]-1-(2-hydrogen phosphona...)copy SMILEScopy InChI
Affinity DataIC50: 230nMAssay Description:Inhibition of human FPPS using IPP and GPPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S75KV9PubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM12578(2-(imidazol-1-yl)-1-hydroxyethylidene-1,1-bisphosp...)copy SMILEScopy InChI
Affinity DataIC50: 250nMAssay Description:Inhibition of human FPPS using IPP and GPPMore data for this Ligand-Target Pair
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
Institute of Biological Chemistry

Curated by ChEMBL
LigandPNGBDBM25259(3-(decyloxy)-1-(2-hydrogen phosphonato-2-phosphono...)copy SMILEScopy InChI
Affinity DataIC50: 280nMpH: 7.0 T: 2°CAssay Description:The inhibitory activity of each test compound was evaluated by monitoring the formation of [14C]GGPP from FPP, using [14C]IPP as the substrate. To co...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2028PVTPubMed
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
Institute of Biological Chemistry

Curated by ChEMBL
LigandPNGBDBM25259(3-(decyloxy)-1-(2-hydrogen phosphonato-2-phosphono...)copy SMILEScopy InChI
Affinity DataIC50: 280nMAssay Description:Inhibition of human GGPPSMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S75KV9PubMed
TargetGeranylgeranyl pyrophosphate synthase BTS1(Saccharomyces cerevisiae (Yeast))
Institute of Biological Chemistry

Curated by ChEMBL
LigandPNGBDBM25288(BPH-629 | [1-hydroxy-2-(3-{8-oxatricyclo[7.4.0.0^{...)copy SMILEScopy InChI
Affinity DataIC50: 280nMAssay Description:Inhibition of Saccharomyces cerevisiae GGPPSMore data for this Ligand-Target Pair
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
Institute of Biological Chemistry

Curated by ChEMBL
LigandPNGBDBM25258(3-(decyloxy)-5-(2-hydrogen phosphonato-2-phosphono...)copy SMILEScopy InChI
Affinity DataIC50: 280nMpH: 7.0 T: 2°CAssay Description:The inhibitory activity of each test compound was evaluated by monitoring the formation of [14C]GGPP from FPP, using [14C]IPP as the substrate. To co...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2028PVTPubMed
TargetGeranylgeranyl pyrophosphate synthase BTS1(Saccharomyces cerevisiae (Yeast))
Institute of Biological Chemistry

Curated by ChEMBL
LigandPNGBDBM25308((1-hydroxy-2-{imidazo[1,2-a]pyridin-3-yl}-1-phosph...)copy SMILEScopy InChI
Affinity DataIC50: 340nMAssay Description:Inhibition of Saccharomyces cerevisiae GGPPSMore data for this Ligand-Target Pair
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
Institute of Biological Chemistry

Curated by ChEMBL
LigandPNGBDBM25260(bisphosphonate, 16 | {2-[dodecyl(methyl)amino]-1-p...)copy SMILEScopy InChI
Affinity DataIC50: 350nMpH: 7.0 T: 2°CAssay Description:The inhibitory activity of each test compound was evaluated by monitoring the formation of [14C]GGPP from FPP, using [14C]IPP as the substrate. To co...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2028PVTPubMed
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
Institute of Biological Chemistry

Curated by ChEMBL
LigandPNGBDBM25261(3-decyl-1-(2-hydrogen phosphonato-2-phosphonoethyl...)copy SMILEScopy InChI
Affinity DataIC50: 400nMpH: 7.0 T: 2°CAssay Description:The inhibitory activity of each test compound was evaluated by monitoring the formation of [14C]GGPP from FPP, using [14C]IPP as the substrate. To co...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2028PVTPubMed
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
Institute of Biological Chemistry

Curated by ChEMBL
LigandPNGBDBM25262(3-bromo-5-(decyloxy)-1-(2-hydrogen phosphonato-2-p...)copy SMILEScopy InChI
Affinity DataIC50: 510nMpH: 7.0 T: 2°CAssay Description:The inhibitory activity of each test compound was evaluated by monitoring the formation of [14C]GGPP from FPP, using [14C]IPP as the substrate. To co...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2028PVTPubMed
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
Institute of Biological Chemistry

Curated by ChEMBL
LigandPNGBDBM25263(bisphosphonate, 19 | {2-[3-(decyloxy)phenyl]-1-hyd...)copy SMILEScopy InChI
Affinity DataIC50: 590nMpH: 7.0 T: 2°CAssay Description:The inhibitory activity of each test compound was evaluated by monitoring the formation of [14C]GGPP from FPP, using [14C]IPP as the substrate. To co...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2028PVTPubMed
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
Institute of Biological Chemistry

Curated by ChEMBL
LigandPNGBDBM25263(bisphosphonate, 19 | {2-[3-(decyloxy)phenyl]-1-hyd...)copy SMILEScopy InChI
Affinity DataIC50: 590nMAssay Description:Inhibition of human GGPPSMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S75KV9PubMed
TargetGeranylgeranyl pyrophosphate synthase BTS1(Saccharomyces cerevisiae (Yeast))
Institute of Biological Chemistry

Curated by ChEMBL
LigandPNGBDBM12578(2-(imidazol-1-yl)-1-hydroxyethylidene-1,1-bisphosp...)copy SMILEScopy InChI
Affinity DataIC50: 660nMAssay Description:Inhibition of Saccharomyces cerevisiae GGPPSMore data for this Ligand-Target Pair
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
Institute of Biological Chemistry

Curated by ChEMBL
LigandPNGBDBM25264(1-(2-hydrogen phosphonato-2-phosphonoethyl)-4-octy...)copy SMILEScopy InChI
Affinity DataIC50: 660nMpH: 7.0 T: 2°CAssay Description:The inhibitory activity of each test compound was evaluated by monitoring the formation of [14C]GGPP from FPP, using [14C]IPP as the substrate. To co...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2028PVTPubMed
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
Institute of Biological Chemistry

Curated by ChEMBL
LigandPNGBDBM25265((1-hydroxy-1-phosphonononyl)phosphonic acid | CHEM...)copy SMILEScopy InChI
Affinity DataIC50: 710nMpH: 7.0 T: 2°CAssay Description:The inhibitory activity of each test compound was evaluated by monitoring the formation of [14C]GGPP from FPP, using [14C]IPP as the substrate. To co...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2028PVTPubMed
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
Institute of Biological Chemistry

Curated by ChEMBL
LigandPNGBDBM25266(BPH-628 | bisphosphonate, 21 | {1-hydroxy-2-[3-(4-...)copy SMILEScopy InChI
Affinity DataIC50: 720nMpH: 7.0 T: 2°CAssay Description:The inhibitory activity of each test compound was evaluated by monitoring the formation of [14C]GGPP from FPP, using [14C]IPP as the substrate. To co...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2028PVTPubMed
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
Institute of Biological Chemistry

Curated by ChEMBL
LigandPNGBDBM25266(BPH-628 | bisphosphonate, 21 | {1-hydroxy-2-[3-(4-...)copy SMILEScopy InChI
Affinity DataIC50: 720nMAssay Description:Inhibition of human GGPPSMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2J2FPubMed
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
Institute of Biological Chemistry

Curated by ChEMBL
LigandPNGBDBM25267(3-(decyloxy)-5-(3,5-difluorophenyl)-1-(2-hydrogen ...)copy SMILEScopy InChI
Affinity DataIC50: 760nMpH: 7.0 T: 2°CAssay Description:The inhibitory activity of each test compound was evaluated by monitoring the formation of [14C]GGPP from FPP, using [14C]IPP as the substrate. To co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2028PVTPubMed
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
Institute of Biological Chemistry

Curated by ChEMBL
LigandPNGBDBM25268(bisphosphonate, 22 | hydrogen {2-[dimethyl(octyl)p...)copy SMILEScopy InChI
Affinity DataIC50: 890nMpH: 7.0 T: 2°CAssay Description:The inhibitory activity of each test compound was evaluated by monitoring the formation of [14C]GGPP from FPP, using [14C]IPP as the substrate. To co...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2028PVTPubMed
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
Institute of Biological Chemistry

Curated by ChEMBL
LigandPNGBDBM25269((1-hydroxy-1-phosphonodecyl)phosphonic acid | CHEM...)copy SMILEScopy InChI
Affinity DataIC50: 890nMpH: 7.0 T: 2°CAssay Description:The inhibitory activity of each test compound was evaluated by monitoring the formation of [14C]GGPP from FPP, using [14C]IPP as the substrate. To co...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2028PVTPubMed
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
Institute of Biological Chemistry

Curated by ChEMBL
LigandPNGBDBM25270([(6E,11E)-2,6,12,16-tetramethyl-9-phosphonoheptade...)copy SMILEScopy InChI
Affinity DataIC50: 980nMpH: 7.0 T: 2°CAssay Description:The inhibitory activity of each test compound was evaluated by monitoring the formation of [14C]GGPP from FPP, using [14C]IPP as the substrate. To co...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2028PVTPubMed
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
Institute of Biological Chemistry

Curated by ChEMBL
LigandPNGBDBM25271(3-[(3,7-dimethyloctyl)oxy]-1-(2-hydrogen phosphona...)copy SMILEScopy InChI
Affinity DataIC50: 1.15E+3nMpH: 7.0 T: 2°CAssay Description:The inhibitory activity of each test compound was evaluated by monitoring the formation of [14C]GGPP from FPP, using [14C]IPP as the substrate. To co...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2028PVTPubMed
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
Institute of Biological Chemistry

Curated by ChEMBL
LigandPNGBDBM25272(CHEMBL238046 | bisphosphonate, 25 | hydrogen {2-[d...)copy SMILEScopy InChI
Affinity DataIC50: 1.23E+3nMpH: 7.0 T: 2°CAssay Description:The inhibitory activity of each test compound was evaluated by monitoring the formation of [14C]GGPP from FPP, using [14C]IPP as the substrate. To co...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2028PVTPubMed
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
Institute of Biological Chemistry

Curated by ChEMBL
LigandPNGBDBM25273(3-(decylamino)-1-(2-hydrogen phosphonato-2-phospho...)copy SMILEScopy InChI
Affinity DataIC50: 1.26E+3nMpH: 7.0 T: 2°CAssay Description:The inhibitory activity of each test compound was evaluated by monitoring the formation of [14C]GGPP from FPP, using [14C]IPP as the substrate. To co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2028PVTPubMed
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
Institute of Biological Chemistry

Curated by ChEMBL
LigandPNGBDBM25274(1-(2-hydrogen phosphonato-2-hydroxy-2-phosphonoeth...)copy SMILEScopy InChI
Affinity DataIC50: 1.38E+3nMpH: 7.0 T: 2°CAssay Description:The inhibitory activity of each test compound was evaluated by monitoring the formation of [14C]GGPP from FPP, using [14C]IPP as the substrate. To co...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2028PVTPubMed
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
Institute of Biological Chemistry

Curated by ChEMBL
LigandPNGBDBM25275(CHEMBL237808 | bisphosphonate, 28 | hydrogen {2-[m...)copy SMILEScopy InChI
Affinity DataIC50: 1.48E+3nMpH: 7.0 T: 2°CAssay Description:The inhibitory activity of each test compound was evaluated by monitoring the formation of [14C]GGPP from FPP, using [14C]IPP as the substrate. To co...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2028PVTPubMed
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