Compile Data Set for Download or QSAR
Found 82 with Last Name = 'soman' and Initial = 's'
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
The Netherlands Institute

Curated by ChEMBL
LigandPNGBDBM50501623(CHEMBL4062929)copy SMILEScopy InChI
Affinity DataKi:  6nMAssay Description:Competitive inhibition of human ATX expressed in HEK293 Flp-In cells assessed as decrease in LPC hydrolysis measured every 30 secs for 90 mins by Lin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetLanosterol 14-alpha demethylase(Rattus norvegicus)
Sinhgad College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50213693((3S,5S,8R,9S,10S,13R,14R,17R)-5,13-dimethyl-17-((R...)copy SMILEScopy InChI
Affinity DataKi:  600nMAssay Description:Inhibition of rat liver LDMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24J0FZ9PubMed
TargetATP-citrate synthase(Homo sapiens (Human))
Sinhgad College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50066683((S)-2-((R)-8-(2,4-dichlorophenyl)-2-hydroxyoctyl)-...)copy SMILEScopy InChI
Affinity DataKi:  1.00E+3nMAssay Description:Inhibition of human ATP citrate lyaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24J0FZ9PubMed
TargetLanosterol synthase(Candida albicans (strain SC5314 / ATCC MYA-2876) (...)
Sinhgad College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50055641(2,2-dimethyl-3-((3E,7E,11E)-3,7,12-trimethyl-14-(6...)copy SMILEScopy InChI
Affinity DataIC50: 0.220nMAssay Description:Inhibition of Candida albicans OSCMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24J0FZ9PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50523667(CHEMBL4560054)copy SMILEScopy InChI
Affinity DataIC50: 1.90nMAssay Description:Inhibition of human PI3Kdelta using PIP2 as substrate after 1 hrMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7FJGPubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50403068(CHEMBL2216870 | IDELALISIB | US9745321, CAL-101)copy SMILEScopy InChI
Affinity DataIC50: 2.10nMAssay Description:Inhibition of human PI3Kdelta using PIP2 as substrate after 1 hrMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
The Netherlands Institute

Curated by ChEMBL
LigandPNGBDBM50187693(CHEMBL3186509)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of human ATX expressed in HEK293 cells using FS-3 as substrate after 15 minsMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50523668(CHEMBL4550603)copy SMILEScopy InChI
Affinity DataIC50: 4.10nMAssay Description:Inhibition of human PI3Kdelta using PIP2 as substrate after 1 hrMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7FJGPubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM92862(US9284315, BEZ-235 | mTOR Inhibitor, BEZ235)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of human PI3Kalpha using PIP2 as substrate after 1 hrMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7FJGPubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50523669(CHEMBL4535169)copy SMILEScopy InChI
Affinity DataIC50: 5.90nMAssay Description:Inhibition of human PI3Kdelta using PIP2 as substrate after 1 hrMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7FJGPubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM92862(US9284315, BEZ-235 | mTOR Inhibitor, BEZ235)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of human PI3Kgamma using PIP2 as substrate after 1 hrMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7FJGPubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50523672(CHEMBL4440218)copy SMILEScopy InChI
Affinity DataIC50: 6.20nMAssay Description:Inhibition of human PI3Kdelta using PIP2 as substrate after 1 hrMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7FJGPubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM92862(US9284315, BEZ-235 | mTOR Inhibitor, BEZ235)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Inhibition of human PI3Kdelta using PIP2 as substrate after 1 hrMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7FJGPubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50523664(CHEMBL4454741)copy SMILEScopy InChI
Affinity DataIC50: 9.5nMAssay Description:Inhibition of human PI3Kdelta using PIP2 as substrate after 1 hrMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7FJGPubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50523673(CHEMBL4589873)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of human PI3Kdelta using PIP2 as substrate after 1 hrMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7FJGPubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50523670(CHEMBL4467333)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of human PI3Kdelta using PIP2 as substrate after 1 hrMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7FJGPubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM92862(US9284315, BEZ-235 | mTOR Inhibitor, BEZ235)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Inhibition of mTOR (unknown origin) assessed as reduction in p70S6K phosphorylationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7FJGPubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50523674(CHEMBL4536349)copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:Inhibition of human PI3Kdelta using PIP2 as substrate after 1 hrMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7FJGPubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50523665(CHEMBL4542493)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of human PI3Kdelta using PIP2 as substrate after 1 hrMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7FJGPubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
The Netherlands Institute

Curated by ChEMBL
LigandPNGBDBM50501623(CHEMBL4062929)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of human ATX expressed in HEK293 Flp-In cells assessed as decrease in choline release from LPC measured every 30 secs for 90 mins by HVA b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Sinhgad College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50094519((R)-1,1,1-Trifluoro-3-{(3-phenoxy-phenyl)-[3-(1,1,...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of CETP assessed as transfer of [3H]cholesterol esters from HDL to LDLMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24J0FZ9PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50523666(CHEMBL4462149)copy SMILEScopy InChI
Affinity DataIC50: 28nMAssay Description:Inhibition of human PI3Kdelta using PIP2 as substrate after 1 hrMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7FJGPubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50523671(CHEMBL4563971)copy SMILEScopy InChI
Affinity DataIC50: 29nMAssay Description:Inhibition of human PI3Kdelta using PIP2 as substrate after 1 hrMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7FJGPubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50523664(CHEMBL4454741)copy SMILEScopy InChI
Affinity DataIC50: 38nMAssay Description:Inhibition of human PI3Kgamma using PIP2 as substrate after 1 hrMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7FJGPubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50523668(CHEMBL4550603)copy SMILEScopy InChI
Affinity DataIC50: 42nMAssay Description:Inhibition of human PI3Kgamma using PIP2 as substrate after 1 hrMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7FJGPubMed
TargetLanosterol synthase(Rattus norvegicus)
Sinhgad College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50055641(2,2-dimethyl-3-((3E,7E,11E)-3,7,12-trimethyl-14-(6...)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Inhibition of rat OSCMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24J0FZ9PubMed
TargetLanosterol synthase(Rattus norvegicus)
Sinhgad College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50213692(2,2-dimethyl-3-((E)-3-methyl-7-((3E,8E)-4,8,12-tri...)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Inhibition of rat OSCMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24J0FZ9PubMed
TargetLanosterol synthase(Rattus norvegicus)
Sinhgad College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50213696(3-((3E,7E)-11-((E)-4,8-dimethylnona-4,7-dienylthio...)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Inhibition of rat OSCMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24J0FZ9PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Homo sapiens (Human))
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM92862(US9284315, BEZ-235 | mTOR Inhibitor, BEZ235)copy SMILEScopy InChI
Affinity DataIC50: 79nMAssay Description:Inhibition of human PI3Kbeta using PIP2 as substrate after 1 hrMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7FJGPubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50403068(CHEMBL2216870 | IDELALISIB | US9745321, CAL-101)copy SMILEScopy InChI
Affinity DataIC50: 92nMAssay Description:Inhibition of human PI3Kgamma using PIP2 as substrate after 1 hrMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7FJGPubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
The Netherlands Institute

Curated by ChEMBL
LigandPNGBDBM50501636(CHEMBL4093316)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition of human ATX expressed in HEK293 Flp-In cells assessed as decrease in choline release from LPC measured every 30 secs for 90 mins by HVA b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22F7RGRPubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50523667(CHEMBL4560054)copy SMILEScopy InChI
Affinity DataIC50: 112nMAssay Description:Inhibition of human PI3Kgamma using PIP2 as substrate after 1 hrMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7FJGPubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
The Netherlands Institute

Curated by ChEMBL
LigandPNGBDBM50501631(CHEMBL4081367)copy SMILEScopy InChI
Affinity DataIC50: 129nMAssay Description:Inhibition of human ATX expressed in HEK293 Flp-In cells assessed as decrease in choline release from LPC measured every 30 secs for 90 mins by HVA b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22F7RGRPubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
The Netherlands Institute

Curated by ChEMBL
LigandPNGBDBM50501630(CHEMBL4105619)copy SMILEScopy InChI
Affinity DataIC50: 202nMAssay Description:Inhibition of human ATX expressed in HEK293 Flp-In cells assessed as decrease in choline release from LPC measured every 30 secs for 90 mins by HVA b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
The Netherlands Institute

Curated by ChEMBL
LigandPNGBDBM50501624(CHEMBL4090866)copy SMILEScopy InChI
Affinity DataIC50: 208nMAssay Description:Inhibition of human ATX expressed in HEK293 Flp-In cells assessed as decrease in choline release from LPC measured every 30 secs for 90 mins by HVA b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22F7RGRPubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Homo sapiens (Human))
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50523668(CHEMBL4550603)copy SMILEScopy InChI
Affinity DataIC50: 241nMAssay Description:Inhibition of human PI3Kbeta using PIP2 as substrate after 1 hrMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7FJGPubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50523668(CHEMBL4550603)copy SMILEScopy InChI
Affinity DataIC50: 289nMAssay Description:Inhibition of human PI3Kalpha using PIP2 as substrate after 1 hrMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7FJGPubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
The Netherlands Institute

Curated by ChEMBL
LigandPNGBDBM50501633(CHEMBL4071554)copy SMILEScopy InChI
Affinity DataIC50: 313nMAssay Description:Inhibition of human ATX expressed in HEK293 Flp-In cells assessed as decrease in choline release from LPC measured every 30 secs for 90 mins by HVA b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22F7RGRPubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Homo sapiens (Human))
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50523664(CHEMBL4454741)copy SMILEScopy InChI
Affinity DataIC50: 342nMAssay Description:Inhibition of human PI3Kbeta using PIP2 as substrate after 1 hrMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7FJGPubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50523664(CHEMBL4454741)copy SMILEScopy InChI
Affinity DataIC50: 421nMAssay Description:Inhibition of human PI3Kalpha using PIP2 as substrate after 1 hrMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7FJGPubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
The Netherlands Institute

Curated by ChEMBL
LigandPNGBDBM50501632(CHEMBL4094214)copy SMILEScopy InChI
Affinity DataIC50: 500nMAssay Description:Inhibition of human ATX expressed in HEK293 Flp-In cells assessed as decrease in choline release from LPC measured every 30 secs for 90 mins by HVA b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22F7RGRPubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
The Netherlands Institute

Curated by ChEMBL
LigandPNGBDBM50501629(CHEMBL4070768)copy SMILEScopy InChI
Affinity DataIC50: 563nMAssay Description:Inhibition of human ATX expressed in HEK293 Flp-In cells assessed as decrease in choline release from LPC measured every 30 secs for 90 mins by HVA b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22F7RGRPubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Homo sapiens (Human))
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50403068(CHEMBL2216870 | IDELALISIB | US9745321, CAL-101)copy SMILEScopy InChI
Affinity DataIC50: 571nMAssay Description:Inhibition of human PI3Kbeta using PIP2 as substrate after 1 hrMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7FJGPubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50523668(CHEMBL4550603)copy SMILEScopy InChI
Affinity DataIC50: 580nMAssay Description:Inhibition of mTOR (unknown origin) assessed as reduction in p70S6K phosphorylationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7FJGPubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Homo sapiens (Human))
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50523667(CHEMBL4560054)copy SMILEScopy InChI
Affinity DataIC50: 589nMAssay Description:Inhibition of human PI3Kbeta using PIP2 as substrate after 1 hrMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7FJGPubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Sinhgad College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50094519((R)-1,1,1-Trifluoro-3-{(3-phenoxy-phenyl)-[3-(1,1,...)copy SMILEScopy InChI
Affinity DataIC50: 600nMAssay Description:Inhibition of human CETP assessed as transfer of [3H]cholesterol esters from HDL to LDL in humna plasmaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24J0FZ9PubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50523664(CHEMBL4454741)copy SMILEScopy InChI
Affinity DataIC50: 676nMAssay Description:Inhibition of mTOR (unknown origin) assessed as reduction in p70S6K phosphorylationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7FJGPubMed
TargetLanosterol synthase(Rattus norvegicus)
Sinhgad College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50213691(1-((5S,6S,8aS)-6-hydroxy-5,8a-dimethyl-octahydrois...)copy SMILEScopy InChI
Affinity DataIC50: 700nMAssay Description:Inhibition of rat OSCMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24J0FZ9PubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
The Netherlands Institute

Curated by ChEMBL
LigandPNGBDBM50501634(CHEMBL4098586)copy SMILEScopy InChI
Affinity DataIC50: 717nMAssay Description:Inhibition of human ATX expressed in HEK293 Flp-In cells assessed as decrease in choline release from LPC measured every 30 secs for 90 mins by HVA b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22F7RGRPubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
The Netherlands Institute

Curated by ChEMBL
LigandPNGBDBM50501627(CHEMBL4085570)copy SMILEScopy InChI
Affinity DataIC50: 814nMAssay Description:Inhibition of human ATX expressed in HEK293 Flp-In cells assessed as decrease in choline release from LPC measured every 30 secs for 90 mins by HVA b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
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