Compile Data Set for Download or QSAR
Found 25 Enz. Inhib. hit(s) with all data for assayid = 1 entry = 50000895
TargetMAP kinase-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
eFFECTOR Therapeutics , 11180 Roselle Street , San Diego , California 92121 , United States.

Curated by ChEMBL
LigandPNGBDBM168214(US9669031, 207 6′-((6-aminopyrimidin-4-yl)am...)copy SMILEScopy InChI
Affinity DataIC50: 0.510nMAssay Description:Inhibition of full length GST-tagged recombinant human MNK1 expressed in insect cells using Ac-TATKSGSTTKNR-NH2 as substrate preincubated for 5 mins ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NC63PSPubMed
TargetMAP kinase-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
eFFECTOR Therapeutics , 11180 Roselle Street , San Diego , California 92121 , United States.

Curated by ChEMBL
LigandPNGBDBM50263269(CHEMBL4076439)copy SMILEScopy InChI
Affinity DataIC50: 0.650nMAssay Description:Inhibition of full length GST-tagged recombinant human MNK1 expressed in insect cells using Ac-TATKSGSTTKNR-NH2 as substrate preincubated for 5 mins ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NC63PSPubMed
TargetMAP kinase-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
eFFECTOR Therapeutics , 11180 Roselle Street , San Diego , California 92121 , United States.

Curated by ChEMBL
LigandPNGBDBM50263254(CHEMBL4094975)copy SMILEScopy InChI
Affinity DataIC50: 0.880nMAssay Description:Inhibition of full length GST-tagged recombinant human MNK1 expressed in insect cells using Ac-TATKSGSTTKNR-NH2 as substrate preincubated for 5 mins ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NC63PSPubMed
TargetMAP kinase-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
eFFECTOR Therapeutics , 11180 Roselle Street , San Diego , California 92121 , United States.

Curated by ChEMBL
LigandPNGBDBM50263255(CHEMBL4065802)copy SMILEScopy InChI
Affinity DataIC50: 1.40nMAssay Description:Inhibition of full length GST-tagged recombinant human MNK1 expressed in insect cells using Ac-TATKSGSTTKNR-NH2 as substrate preincubated for 5 mins ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NC63PSPubMed
TargetMAP kinase-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
eFFECTOR Therapeutics , 11180 Roselle Street , San Diego , California 92121 , United States.

Curated by ChEMBL
LigandPNGBDBM50263264(CHEMBL4094080)copy SMILEScopy InChI
Affinity DataIC50: 1.5nMAssay Description:Inhibition of full length GST-tagged recombinant human MNK1 expressed in insect cells using Ac-TATKSGSTTKNR-NH2 as substrate preincubated for 5 mins ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NC63PSPubMed
TargetMAP kinase-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
eFFECTOR Therapeutics , 11180 Roselle Street , San Diego , California 92121 , United States.

Curated by ChEMBL
LigandPNGBDBM168222(US9669031, 51 N-[6-[[8-chloro-3-(3-chlorophenyl)-3...)copy SMILEScopy InChI
Affinity DataIC50: 1.60nMAssay Description:Inhibition of full length GST-tagged recombinant human MNK1 expressed in insect cells using Ac-TATKSGSTTKNR-NH2 as substrate preincubated for 5 mins ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NC63PSPubMed
TargetMAP kinase-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
eFFECTOR Therapeutics , 11180 Roselle Street , San Diego , California 92121 , United States.

Curated by ChEMBL
LigandPNGBDBM297345(N-(6-((1-oxoisoindolin-5-yl)amino)pyrimidin-4-yl)c...)copy SMILEScopy InChI
Affinity DataIC50: 1.90nMAssay Description:Inhibition of full length GST-tagged recombinant human MNK1 expressed in insect cells using Ac-TATKSGSTTKNR-NH2 as substrate preincubated for 5 mins ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NC63PSPubMed
TargetMAP kinase-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
eFFECTOR Therapeutics , 11180 Roselle Street , San Diego , California 92121 , United States.

Curated by ChEMBL
LigandPNGBDBM50263253(CHEMBL4067557)copy SMILEScopy InChI
Affinity DataIC50: 2.20nMAssay Description:Inhibition of full length GST-tagged recombinant human MNK1 expressed in insect cells using Ac-TATKSGSTTKNR-NH2 as substrate preincubated for 5 mins ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NC63PSPubMed
TargetMAP kinase-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
eFFECTOR Therapeutics , 11180 Roselle Street , San Diego , California 92121 , United States.

Curated by ChEMBL
LigandPNGBDBM50263263(CHEMBL4073443)copy SMILEScopy InChI
Affinity DataIC50: 2.40nMAssay Description:Inhibition of full length GST-tagged recombinant human MNK1 expressed in insect cells using Ac-TATKSGSTTKNR-NH2 as substrate preincubated for 5 mins ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NC63PSPubMed
TargetMAP kinase-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
eFFECTOR Therapeutics , 11180 Roselle Street , San Diego , California 92121 , United States.

Curated by ChEMBL
LigandPNGBDBM164271(US9669031, 10 N-(6-((3,3-dimethyl-1,5-dioxo-1,2,3,...)copy SMILEScopy InChI
Affinity DataIC50: 2.70nMAssay Description:Inhibition of full length GST-tagged recombinant human MNK1 expressed in insect cells using Ac-TATKSGSTTKNR-NH2 as substrate preincubated for 5 mins ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NC63PSPubMed
TargetMAP kinase-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
eFFECTOR Therapeutics , 11180 Roselle Street , San Diego , California 92121 , United States.

Curated by ChEMBL
LigandPNGBDBM168216(US9669031, 181 3,3-dimethyl-1,5-dioxo-6-(pyrimidin...)copy SMILEScopy InChI
Affinity DataIC50: 3.30nMAssay Description:Inhibition of full length GST-tagged recombinant human MNK1 expressed in insect cells using Ac-TATKSGSTTKNR-NH2 as substrate preincubated for 5 mins ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NC63PSPubMed
TargetMAP kinase-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
eFFECTOR Therapeutics , 11180 Roselle Street , San Diego , California 92121 , United States.

Curated by ChEMBL
LigandPNGBDBM168241(US9669031, 69 8-fluoro-3,3-dimethyl-6-(pyrimidin-4...)copy SMILEScopy InChI
Affinity DataIC50: 6.5nMAssay Description:Inhibition of full length GST-tagged recombinant human MNK1 expressed in insect cells using Ac-TATKSGSTTKNR-NH2 as substrate preincubated for 5 mins ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NC63PSPubMed
TargetMAP kinase-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
eFFECTOR Therapeutics , 11180 Roselle Street , San Diego , California 92121 , United States.

Curated by ChEMBL
LigandPNGBDBM168239(US9669031, 67 3,3,8-trimethyl-6-(pyrimidin-4-ylami...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of full length GST-tagged recombinant human MNK1 expressed in insect cells using Ac-TATKSGSTTKNR-NH2 as substrate preincubated for 5 mins ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NC63PSPubMed
TargetMAP kinase-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
eFFECTOR Therapeutics , 11180 Roselle Street , San Diego , California 92121 , United States.

Curated by ChEMBL
LigandPNGBDBM297336(5-((9H-purin-6-yl)amino)isoindolin-1-one (Cpd. No....)copy SMILEScopy InChI
Affinity DataIC50: 23nMAssay Description:Inhibition of full length GST-tagged recombinant human MNK1 expressed in insect cells using Ac-TATKSGSTTKNR-NH2 as substrate preincubated for 5 mins ...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NC63PSPubMed
TargetMAP kinase-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
eFFECTOR Therapeutics , 11180 Roselle Street , San Diego , California 92121 , United States.

Curated by ChEMBL
LigandPNGBDBM297342(3-methyl-5-(pyrimidin-4-ylamino)isoindolin-1-one (...)copy SMILEScopy InChI
Affinity DataIC50: 28nMAssay Description:Inhibition of full length GST-tagged recombinant human MNK1 expressed in insect cells using Ac-TATKSGSTTKNR-NH2 as substrate preincubated for 5 mins ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NC63PSPubMed
TargetMAP kinase-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
eFFECTOR Therapeutics , 11180 Roselle Street , San Diego , California 92121 , United States.

Curated by ChEMBL
LigandPNGBDBM50326413(4-(9H-purin-6-ylamino)benzamide | CHEMBL1241463)copy SMILEScopy InChI
Affinity DataIC50: 60nMAssay Description:Inhibition of full length GST-tagged recombinant human MNK1 expressed in insect cells using Ac-TATKSGSTTKNR-NH2 as substrate preincubated for 5 mins ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NC63PSPubMed
TargetMAP kinase-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
eFFECTOR Therapeutics , 11180 Roselle Street , San Diego , California 92121 , United States.

Curated by ChEMBL
LigandPNGBDBM164243(US9669031, 2 3,3-dimethyl-6-(pyrimidin-4-ylamino)-...)copy SMILEScopy InChI
Affinity DataIC50: 60nMAssay Description:Inhibition of full length GST-tagged recombinant human MNK1 expressed in insect cells using Ac-TATKSGSTTKNR-NH2 as substrate preincubated for 5 mins ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NC63PSPubMed
TargetMAP kinase-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
eFFECTOR Therapeutics , 11180 Roselle Street , San Diego , California 92121 , United States.

Curated by ChEMBL
LigandPNGBDBM297347(3,3-dimethyl-5-(pyrimidin-4-ylamino)isoindolin-1-o...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition of full length GST-tagged recombinant human MNK1 expressed in insect cells using Ac-TATKSGSTTKNR-NH2 as substrate preincubated for 5 mins ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NC63PSPubMed
TargetMAP kinase-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
eFFECTOR Therapeutics , 11180 Roselle Street , San Diego , California 92121 , United States.

Curated by ChEMBL
LigandPNGBDBM50263251(CHEMBL4071844)copy SMILEScopy InChI
Affinity DataIC50: 690nMAssay Description:Inhibition of full length GST-tagged recombinant human MNK1 expressed in insect cells using Ac-TATKSGSTTKNR-NH2 as substrate preincubated for 5 mins ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NC63PSPubMed
TargetMAP kinase-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
eFFECTOR Therapeutics , 11180 Roselle Street , San Diego , California 92121 , United States.

Curated by ChEMBL
LigandPNGBDBM50326424(3-(pyridin-4-yl)imidazo[1,2-b]pyridazine | CHEMBL1...)copy SMILEScopy InChI
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of full length GST-tagged recombinant human MNK1 expressed in insect cells using Ac-TATKSGSTTKNR-NH2 as substrate preincubated for 5 mins ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NC63PSPubMed
TargetMAP kinase-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
eFFECTOR Therapeutics , 11180 Roselle Street , San Diego , California 92121 , United States.

Curated by ChEMBL
LigandPNGBDBM50263252(CHEMBL4065855)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of full length GST-tagged recombinant human MNK1 expressed in insect cells using Ac-TATKSGSTTKNR-NH2 as substrate preincubated for 5 mins ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NC63PSPubMed
TargetMAP kinase-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
eFFECTOR Therapeutics , 11180 Roselle Street , San Diego , California 92121 , United States.

Curated by ChEMBL
LigandPNGBDBM50263239(CHEMBL4101302)copy SMILEScopy InChI
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibition of full length GST-tagged recombinant human MNK1 expressed in insect cells using Ac-TATKSGSTTKNR-NH2 as substrate preincubated for 5 mins ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NC63PSPubMed
TargetMAP kinase-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
eFFECTOR Therapeutics , 11180 Roselle Street , San Diego , California 92121 , United States.

Curated by ChEMBL
LigandPNGBDBM50263271(CHEMBL4063216)copy SMILEScopy InChI
Affinity DataIC50: 4.70E+3nMAssay Description:Inhibition of full length GST-tagged recombinant human MNK1 expressed in insect cells using Ac-TATKSGSTTKNR-NH2 as substrate preincubated for 5 mins ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NC63PSPubMed
TargetMAP kinase-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
eFFECTOR Therapeutics , 11180 Roselle Street , San Diego , California 92121 , United States.

Curated by ChEMBL
LigandPNGBDBM50326412(4-(3-(piperidin-4-yl)-1H-pyrazol-5-yl)pyridine | C...)copy SMILEScopy InChI
Affinity DataIC50: 5.50E+3nMAssay Description:Inhibition of full length GST-tagged recombinant human MNK1 expressed in insect cells using Ac-TATKSGSTTKNR-NH2 as substrate preincubated for 5 mins ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NC63PSPubMed
TargetMAP kinase-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
eFFECTOR Therapeutics , 11180 Roselle Street , San Diego , California 92121 , United States.

Curated by ChEMBL
LigandPNGBDBM50263250(CHEMBL4091092)copy SMILEScopy InChI
Affinity DataIC50: 6.40E+3nMAssay Description:Inhibition of full length GST-tagged recombinant human MNK1 expressed in insect cells using Ac-TATKSGSTTKNR-NH2 as substrate preincubated for 5 mins ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NC63PSPubMed