Found 5 Enz. Inhib. hit(s) with Target = 'MAP kinase-interacting serine/threonine-protein kinase 1' and Ligand = 'BDBM50263263' TargetMAP kinase-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
University of South Australia
Curated by ChEMBL
University of South Australia
Curated by ChEMBL
Affinity DataKi: 5nMAssay Description:Inhibition of recombinant GST-tagged MNK1 (unknown origin) using eIF4E-derived peptide as substrate in presence of ATP at km concentration by ADP-Glo...More data for this Ligand-Target Pair
TargetMAP kinase-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
University of South Australia
Curated by ChEMBL
University of South Australia
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of MNK1 (unknown origin) expressed in HEK293 cells assessed as decrease in eIF4E phosphorylation at Ser209 residues by Western blot analys...More data for this Ligand-Target Pair
TargetMAP kinase-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
University of South Australia
Curated by ChEMBL
University of South Australia
Curated by ChEMBL
TargetMAP kinase-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
University of South Australia
Curated by ChEMBL
University of South Australia
Curated by ChEMBL
Affinity DataIC50: 2.40nMAssay Description:Inhibition of full length GST-tagged recombinant human MNK1 expressed in insect cells using Ac-TATKSGSTTKNR-NH2 as substrate preincubated for 5 mins ...More data for this Ligand-Target Pair
TargetMAP kinase-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
University of South Australia
Curated by ChEMBL
University of South Australia
Curated by ChEMBL
Affinity DataIC50: 3.30nMAssay Description:Inhibition of recombinant human N-terminal DYKDDDDK-tagged MNK1(1 to 424 residues) expressed in baculovirus expression system using TATKSGSTTKNR as s...More data for this Ligand-Target Pair
