Compile Data Set for Download or QSAR
Found 44 of ic50 for UniProtKB: P49116
TargetNuclear receptor subfamily 2 group C member 2(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM375312(US9908872, Compound (I-9))copy SMILEScopy InChI
Affinity DataIC50: 2.43nMAssay Description:The in vitro activity of the compounds described herein in inhibiting TAK1, HCK, and other kinases were obtained using an Invitrogen Select Screening...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2668GH3US Patent
TargetNuclear receptor subfamily 2 group C member 2(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM375310(US9908872, Compound (I-8))copy SMILEScopy InChI
Affinity DataIC50: 5.33nMAssay Description:The in vitro activity of the compounds described herein in inhibiting TAK1, HCK, and other kinases were obtained using an Invitrogen Select Screening...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2668GH3US Patent
TargetNuclear receptor subfamily 2 group C member 2(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM375276(US10597387, Compound (I-1) | US9908872, Compound (...)copy SMILEScopy InChI
Affinity DataIC50: 7.40nMAssay Description:The in vitro activity of the compounds described herein in inhibiting TAK1, HCK, and other kinases were obtained using an Invitrogen Select Screening...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2668GH3US Patent
TargetNuclear receptor subfamily 2 group C member 2(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM50379186(CEP-11981 | CHEMBL2010872)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Inhibition of human TAK1 using ATP as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2XHWPubMed
TargetNuclear receptor subfamily 2 group C member 2(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM375281(US10597387, Compound (I-4) | US9908872, Compound (...)copy SMILEScopy InChI
Affinity DataIC50: 22.8nMAssay Description:The in vitro activity of the compounds described herein in inhibiting TAK1, HCK, and other kinases were obtained using an Invitrogen Select Screening...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2668GH3US Patent
TargetNuclear receptor subfamily 2 group C member 2(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM375307(US10597387, Compound (I-6) | US9908872, Compound (...)copy SMILEScopy InChI
Affinity DataIC50: 29.9nMAssay Description:The in vitro activity of the compounds described herein in inhibiting TAK1, HCK, and other kinases were obtained using an Invitrogen Select Screening...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2668GH3US Patent
TargetNuclear receptor subfamily 2 group C member 2(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM439303(US10633348, Compound (A-17))copy SMILEScopy InChI
Affinity DataIC50: 45nMAssay Description:The in vitro activity of the compounds described herein in inhibiting TAK1, HCK and other kinases were obtained using an Invitrogen Select Screening ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22Z18JRUS Patent
TargetNuclear receptor subfamily 2 group C member 2(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM439318(US10633348, Compound (A-14))copy SMILEScopy InChI
Affinity DataIC50: 53.8nMAssay Description:The in vitro activity of the compounds described herein in inhibiting TAK1, HCK and other kinases were obtained using an Invitrogen Select Screening ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22Z18JRUS Patent
TargetNuclear receptor subfamily 2 group C member 2(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM375308(US10597387, Compound (I-7) | US9908872, Compound (...)copy SMILEScopy InChI
Affinity DataIC50: 56.5nMAssay Description:The in vitro activity of the compounds described herein in inhibiting TAK1, HCK, and other kinases were obtained using an Invitrogen Select Screening...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2668GH3US Patent
TargetNuclear receptor subfamily 2 group C member 2(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM50086441(CHEMBL3426225 | US10266537, Compound 3)copy SMILEScopy InChI
Affinity DataIC50: 61nMAssay Description:Inhibition of human TAK1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38V91PubMed
TargetNuclear receptor subfamily 2 group C member 2(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM375280(US10597387, Compound (I-3) | US9908872, Compound (...)copy SMILEScopy InChI
Affinity DataIC50: 62.2nMAssay Description:The in vitro activity of the compounds described herein in inhibiting TAK1, HCK, and other kinases were obtained using an Invitrogen Select Screening...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2668GH3US Patent
TargetNuclear receptor subfamily 2 group C member 2(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM439308(US10633348, Compound (A-6))copy SMILEScopy InChI
Affinity DataIC50: 63.5nMAssay Description:The in vitro activity of the compounds described herein in inhibiting TAK1, HCK and other kinases were obtained using an Invitrogen Select Screening ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22Z18JRUS Patent
TargetNuclear receptor subfamily 2 group C member 2(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM439309(US10633348, Compound (A-7))copy SMILEScopy InChI
Affinity DataIC50: 71.7nMAssay Description:The in vitro activity of the compounds described herein in inhibiting TAK1, HCK and other kinases were obtained using an Invitrogen Select Screening ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22Z18JRUS Patent
TargetNuclear receptor subfamily 2 group C member 2(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM439316(US10633348, Compound (A-12))copy SMILEScopy InChI
Affinity DataIC50: 76.2nMAssay Description:The in vitro activity of the compounds described herein in inhibiting TAK1, HCK and other kinases were obtained using an Invitrogen Select Screening ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22Z18JRUS Patent
TargetNuclear receptor subfamily 2 group C member 2(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM439305(US10633348, Compound (A-3))copy SMILEScopy InChI
Affinity DataIC50: 92nMAssay Description:The in vitro activity of the compounds described herein in inhibiting TAK1, HCK and other kinases were obtained using an Invitrogen Select Screening ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22Z18JRUS Patent
TargetNuclear receptor subfamily 2 group C member 2(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM439307(US10633348, Compound (A-5))copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:The in vitro activity of the compounds described herein in inhibiting TAK1, HCK and other kinases were obtained using an Invitrogen Select Screening ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22Z18JRUS Patent
TargetNuclear receptor subfamily 2 group C member 2(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM439304(US10633348, Compound (A-2))copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:The in vitro activity of the compounds described herein in inhibiting TAK1, HCK and other kinases were obtained using an Invitrogen Select Screening ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22Z18JRUS Patent
TargetNuclear receptor subfamily 2 group C member 2(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM375299(US10597387, Compound (I-5) | US9908872, Compound (...)copy SMILEScopy InChI
Affinity DataIC50: 117nMAssay Description:The in vitro activity of the compounds described herein in inhibiting TAK1, HCK, and other kinases were obtained using an Invitrogen Select Screening...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2668GH3US Patent
TargetNuclear receptor subfamily 2 group C member 2(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM50604141(CHEMBL5188433)copy SMILES
Affinity DataIC50: 120nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TH8RSPPubMed
TargetNuclear receptor subfamily 2 group C member 2(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM50584720(CHEMBL5088153)copy SMILES
Affinity DataIC50: 126nMAssay Description:Inhibition of human TAK1 in presence of ATP by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2377DMNPubMed
TargetNuclear receptor subfamily 2 group C member 2(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM439319(US10633348, Compound (A-15))copy SMILEScopy InChI
Affinity DataIC50: 136nMAssay Description:The in vitro activity of the compounds described herein in inhibiting TAK1, HCK and other kinases were obtained using an Invitrogen Select Screening ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22Z18JRUS Patent
TargetNuclear receptor subfamily 2 group C member 2(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM50604140(CHEMBL5185000)copy SMILES
Affinity DataIC50: 260nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TH8RSPPubMed
TargetNuclear receptor subfamily 2 group C member 2(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM438001(US10633348, Compound (A-1) | US10633348, Compound ...)copy SMILEScopy InChI
Affinity DataIC50: 364nMAssay Description:The in vitro activity of the compounds described herein in inhibiting TAK1, HCK and other kinases were obtained using an Invitrogen Select Screening ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22Z18JRUS Patent
TargetNuclear receptor subfamily 2 group C member 2(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM439317(US10633348, Compound (A-13))copy SMILEScopy InChI
Affinity DataIC50: 400nMAssay Description:The in vitro activity of the compounds described herein in inhibiting TAK1, HCK and other kinases were obtained using an Invitrogen Select Screening ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22Z18JRUS Patent
TargetNuclear receptor subfamily 2 group C member 2(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM438001(US10633348, Compound (A-1) | US10633348, Compound ...)copy SMILEScopy InChI
Affinity DataIC50: 487nMAssay Description:The in vitro activity of the compounds described herein in inhibiting TAK1, HCK and other kinases were obtained using an Invitrogen Select Screening ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22Z18JRUS Patent
TargetNuclear receptor subfamily 2 group C member 2(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM439306(US10633348, Compound (A-4))copy SMILEScopy InChI
Affinity DataIC50: 591nMAssay Description:The in vitro activity of the compounds described herein in inhibiting TAK1, HCK and other kinases were obtained using an Invitrogen Select Screening ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22Z18JRUS Patent
TargetNuclear receptor subfamily 2 group C member 2(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM400813(QL-X-138 | US10000483, Compound II-6)copy SMILEScopy InChI
Affinity DataIC50: 717nMAssay Description:DiscoverX binding assays were performed according to published methods (Fabian et al., Nat. Biotechnol. 23, 329-36 (2005); Davis et al., Nat. Biotech...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QF8W63US Patent
TargetNuclear receptor subfamily 2 group C member 2(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM439314(US10633348, Compound (A-18))copy SMILEScopy InChI
Affinity DataIC50: 1.75E+3nMAssay Description:The in vitro activity of the compounds described herein in inhibiting TAK1, HCK and other kinases were obtained using an Invitrogen Select Screening ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22Z18JRUS Patent
TargetNuclear receptor subfamily 2 group C member 2(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM50245587(CHEMBL4077064 | US10000483, Compound II-4)copy SMILEScopy InChI
Affinity DataIC50: 3.30E+3nMAssay Description:DiscoverX binding assays were performed according to published methods (Fabian et al., Nat. Biotechnol. 23, 329-36 (2005); Davis et al., Nat. Biotech...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QF8W63US Patent
TargetNuclear receptor subfamily 2 group C member 2(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM102620(BMX-IN-1 | N-[5-[9-[4-(methanesulfonamido)phenyl]-...)copy SMILEScopy InChI
Affinity DataIC50: 3.30E+3nMAssay Description:DiscoverX binding assays were performed according to published methods (Fabian et al., Nat. Biotechnol. 23, 329-36 (2005); Davis et al., Nat. Biotech...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QF8W63US Patent
TargetNuclear receptor subfamily 2 group C member 2(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM375307(US10597387, Compound (I-6) | US9908872, Compound (...)copy SMILEScopy InChI
Affinity DataIC50: 3.33E+3nMAssay Description:The in vitro activity of the compounds described herein in inhibiting TAK1, HCK, and other kinases were obtained using an Invitrogen Select Screening...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZC85X9US Patent
TargetNuclear receptor subfamily 2 group C member 2(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM439312(US10633348, Compound (A-9))copy SMILEScopy InChI
Affinity DataIC50: 7.31E+3nMAssay Description:The in vitro activity of the compounds described herein in inhibiting TAK1, HCK and other kinases were obtained using an Invitrogen Select Screening ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22Z18JRUS Patent
TargetNuclear receptor subfamily 2 group C member 2(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM375276(US10597387, Compound (I-1) | US9908872, Compound (...)copy SMILEScopy InChI
Affinity DataIC50: 8.21E+3nMAssay Description:The in vitro activity of the compounds described herein in inhibiting TAK1, HCK, and other kinases were obtained using an Invitrogen Select Screening...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZC85X9US Patent
TargetNuclear receptor subfamily 2 group C member 2(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM439315(US10633348, Compound (A-11))copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:The in vitro activity of the compounds described herein in inhibiting TAK1, HCK and other kinases were obtained using an Invitrogen Select Screening ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22Z18JRUS Patent
TargetNuclear receptor subfamily 2 group C member 2(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM439313(US10633348, Compound (A-10))copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:The in vitro activity of the compounds described herein in inhibiting TAK1, HCK and other kinases were obtained using an Invitrogen Select Screening ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22Z18JRUS Patent
TargetNuclear receptor subfamily 2 group C member 2(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM375299(US10597387, Compound (I-5) | US9908872, Compound (...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:The in vitro activity of the compounds described herein in inhibiting TAK1, HCK, and other kinases were obtained using an Invitrogen Select Screening...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZC85X9US Patent
TargetNuclear receptor subfamily 2 group C member 2(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM50386693(CHEMBL2048912)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of N-terminus FLAG-tagged TAK1 expressed in baculovirus expression system using [gamma-33P]-ATP measured after 60 mins by scintillation co...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2474BX1PubMed
TargetNuclear receptor subfamily 2 group C member 2(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM50334268(CHEMBL1642655 | CHEMBL2205637 | N-(6-(1H-imidazol-...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of TAK1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M32WXVPubMed
TargetNuclear receptor subfamily 2 group C member 2(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM50429867(CHEMBL2333365)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of TAK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZC847XPubMed
TargetNuclear receptor subfamily 2 group C member 2(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM50432373(CHEMBL2348417)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of N-terminal FLAG-tagged TAK1 (unknown origin) expressed in baculovirus expression system incubated for 5 mins prior to [gamma-33P]ATP ad...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TT4S9DPubMed
TargetNuclear receptor subfamily 2 group C member 2(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM50357884(CHEMBL1916359)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human TAK1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2HKRPubMed
TargetNuclear receptor subfamily 2 group C member 2(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM50358430(CHEMBL1614725)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of N-terminus flag-tagged TAK1 expressed in baculovirus infected insect cells using [gamma33P]ATP as substrate after 60 mins by scintillat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23R0T93PubMed
TargetNuclear receptor subfamily 2 group C member 2(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM357013(5-Phenyl-N-(pyridin-2-ylmethyl)-2-(pyrimidin-5-yl)...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:The analyses were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and subst...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29Z975MUS Patent
TargetNuclear receptor subfamily 2 group C member 2(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM50239229(CHEMBL4097255 | US10676460, Example 1)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:The analyses were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and subst...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QZ2F1CUS Patent