Compile Data Set for Download or QSAR
Found 119 of ec50 data for polymerid = 3579
TargetAmyloid-beta precursor protein(Homo sapiens (Human))TBA
LigandPNGBDBM4078(6,7,13,14-tetrahydroxy-2,9-dioxatetracyclo[6.6.2.0...)copy SMILEScopy InChI
Affinity DataEC50:  1.70nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H70KVXPubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))TBA
LigandPNGBDBM50085536(3,4,5-Trihydroxybenzoate, X | 3,4,5-trihydroxybenz...)copy SMILEScopy InChI
Affinity DataEC50:  1.70nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H70KVXPubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))TBA
LigandPNGBDBM50595332(CHEMBL5179584)copy SMILES
Affinity DataEC50:  1.90nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H70KVXPubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))TBA
LigandPNGBDBM50085536(3,4,5-Trihydroxybenzoate, X | 3,4,5-trihydroxybenz...)copy SMILEScopy InChI
Affinity DataEC50:  3.20nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H70KVXPubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))TBA
LigandPNGBDBM50242279(6,7,8,11,12,13,22,23-octahydroxy-3,16-dioxo-21-(3,...)copy SMILEScopy InChI
Affinity DataEC50:  3.20nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H70KVXPubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))TBA
LigandPNGBDBM455363(7-(2,3-Difluorophenyl)-N4,5,5-trimethyl-N2-((1R,5S...)copy SMILEScopy InChI
Affinity DataEC50:  6nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μl in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27M0C0JUS Patent
TargetAmyloid-beta precursor protein(Homo sapiens (Human))TBA
LigandPNGBDBM4078(6,7,13,14-tetrahydroxy-2,9-dioxatetracyclo[6.6.2.0...)copy SMILEScopy InChI
Affinity DataEC50:  6nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H70KVXPubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))TBA
LigandPNGBDBM50595332(CHEMBL5179584)copy SMILES
Affinity DataEC50:  6.70nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H70KVXPubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))TBA
LigandPNGBDBM50242278(CHEMBL506069 | Geraniin | geraniiin)copy SMILEScopy InChI
Affinity DataEC50:  6.70nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H70KVXPubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))TBA
LigandPNGBDBM50242279(6,7,8,11,12,13,22,23-octahydroxy-3,16-dioxo-21-(3,...)copy SMILEScopy InChI
Affinity DataEC50:  8.90nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H70KVXPubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))TBA
LigandPNGBDBM455355(2-((7-(4-Fluorophenyl)-2-(((1R,5S,8s)-3-(6-methoxy...)copy SMILEScopy InChI
Affinity DataEC50:  9nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μl in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27M0C0JUS Patent
TargetAmyloid-beta precursor protein(Homo sapiens (Human))TBA
LigandPNGBDBM455353(7-(2,4-Difluorophenyl)-N2-((1R,5S,8s)-3-(6-methoxy...)copy SMILEScopy InChI
Affinity DataEC50:  9nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μl in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27M0C0JUS Patent
TargetAmyloid-beta precursor protein(Homo sapiens (Human))TBA
LigandPNGBDBM455358(7-(2,3-Difluorophenyl)-N4,5,5-trimethyl-N2-((1R,5S...)copy SMILEScopy InChI
Affinity DataEC50:  9nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μl in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27M0C0JUS Patent
TargetAmyloid-beta precursor protein(Homo sapiens (Human))TBA
LigandPNGBDBM50242278(CHEMBL506069 | Geraniin | geraniiin)copy SMILEScopy InChI
Affinity DataEC50:  10nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H70KVXPubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))TBA
LigandPNGBDBM455364(7-(2,3-Difluorophenyl)-N4,5,5-trimethyl-N2-((1R,5S...)copy SMILEScopy InChI
Affinity DataEC50:  10nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μl in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27M0C0JUS Patent
TargetAmyloid-beta precursor protein(Homo sapiens (Human))TBA
LigandPNGBDBM455341(N2-((1R,5S,8s)-3-(6-Chloropyridazin-4-yl)-3-azabic...)copy SMILEScopy InChI
Affinity DataEC50:  11nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μl in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27M0C0JUS Patent
TargetAmyloid-beta precursor protein(Homo sapiens (Human))TBA
LigandPNGBDBM455344(7-(4-Fluorophenyl)-N4-methyl-N2-((1R,5S,8s)-3-(6-m...)copy SMILEScopy InChI
Affinity DataEC50:  12nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μl in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27M0C0JUS Patent
TargetAmyloid-beta precursor protein(Homo sapiens (Human))TBA
LigandPNGBDBM455354(2-((7-(4-Fluorophenyl)-5,5-dimethyl-2-(((1R,5S,8s)...)copy SMILEScopy InChI
Affinity DataEC50:  12nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μl in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27M0C0JUS Patent
TargetAmyloid-beta precursor protein(Homo sapiens (Human))TBA
LigandPNGBDBM455336(7-(4-Fluorophenyl)-N2-((1R,5S,8s)-3-(6-methoxypyri...)copy SMILEScopy InChI
Affinity DataEC50:  12nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μl in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27M0C0JUS Patent
TargetAmyloid-beta precursor protein(Homo sapiens (Human))TBA
LigandPNGBDBM455334(7-(4-Fluorophenyl)-N4,5,5-trimethyl-N2-((1R,5S,8s)...)copy SMILEScopy InChI
Affinity DataEC50:  14nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μl in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27M0C0JUS Patent
TargetAmyloid-beta precursor protein(Homo sapiens (Human))TBA
LigandPNGBDBM455349(7-(2,4-Difluorophenyl)-N4,5,5-trimethyl-N2-((1R,5S...)copy SMILEScopy InChI
Affinity DataEC50:  14nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μl in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27M0C0JUS Patent
TargetAmyloid-beta precursor protein(Homo sapiens (Human))TBA
LigandPNGBDBM455345(7-(3,4-Difluorophenyl)-N2-((1R,5S,8s)-3-(6-methoxy...)copy SMILEScopy InChI
Affinity DataEC50:  16nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μl in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27M0C0JUS Patent
TargetAmyloid-beta precursor protein(Homo sapiens (Human))TBA
LigandPNGBDBM455359((S)- or (R)-7-(4-Fluorophenyl)-N4,5-dimethyl-N2-((...)copy SMILEScopy InChI
Affinity DataEC50:  16nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μl in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27M0C0JUS Patent
TargetAmyloid-beta precursor protein(Homo sapiens (Human))TBA
LigandPNGBDBM455360((R)- or (S)-7-(4-Fluorophenyl)-N4,5-dimethyl-N2-((...)copy SMILEScopy InChI
Affinity DataEC50:  17nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μl in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27M0C0JUS Patent
TargetAmyloid-beta precursor protein(Homo sapiens (Human))TBA
LigandPNGBDBM455346(7-(4-Fluorophenyl)-N4,5,5-trimethyl-N2-((1R,5S,8s)...)copy SMILEScopy InChI
Affinity DataEC50:  19nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μl in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27M0C0JUS Patent
TargetAmyloid-beta precursor protein(Homo sapiens (Human))TBA
LigandPNGBDBM455337(7-(4-Fluorophenyl)-N2-((1R,5S,8s)-3-(2-methoxypyri...)copy SMILEScopy InChI
Affinity DataEC50:  23nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μl in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27M0C0JUS Patent
TargetAmyloid-beta precursor protein(Homo sapiens (Human))TBA
LigandPNGBDBM455343(7-(3,4-Difluorophenyl)-N4,5,5-trimethyl-N2-((1R,5S...)copy SMILEScopy InChI
Affinity DataEC50:  24nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μl in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27M0C0JUS Patent
TargetAmyloid-beta precursor protein(Homo sapiens (Human))TBA
LigandPNGBDBM455357(8-(4-Fluorophenyl)-N2-((1R,5S,8s)-3-(6-methoxypyri...)copy SMILEScopy InChI
Affinity DataEC50:  24nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μl in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27M0C0JUS Patent
TargetAmyloid-beta precursor protein(Homo sapiens (Human))TBA
LigandPNGBDBM455338(N2-((1R,5S,8s)-3-(6-Chloropyrimidin-4-yl)-3-azabic...)copy SMILEScopy InChI
Affinity DataEC50:  31nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μl in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27M0C0JUS Patent
TargetAmyloid-beta precursor protein(Homo sapiens (Human))TBA
LigandPNGBDBM455350(7-(2,4-Difluorophenyl)-N4,5,5-trimethyl-N2-((1R,5S...)copy SMILEScopy InChI
Affinity DataEC50:  31nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μl in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27M0C0JUS Patent
TargetAmyloid-beta precursor protein(Homo sapiens (Human))TBA
LigandPNGBDBM455342(7-(3,4-Difluorophenyl)-N4,5,5-trimethyl-N2-((1R,5S...)copy SMILEScopy InChI
Affinity DataEC50:  33nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μl in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27M0C0JUS Patent
TargetAmyloid-beta precursor protein(Homo sapiens (Human))TBA
LigandPNGBDBM455335(7-(4-Fluorophenyl)-N4,5,5-trimethyl-N2-((1R,5S,8s)...)copy SMILEScopy InChI
Affinity DataEC50:  34nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μl in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27M0C0JUS Patent
TargetAmyloid-beta precursor protein(Homo sapiens (Human))TBA
LigandPNGBDBM455356(8-(4-Fluorophenyl)-N4,5,5-trimethyl-N2-((1R,5S,8s)...)copy SMILEScopy InChI
Affinity DataEC50:  35nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μl in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27M0C0JUS Patent
TargetAmyloid-beta precursor protein(Homo sapiens (Human))TBA
LigandPNGBDBM50236004(CHEMBL4101809)copy SMILEScopy InChI
Affinity DataEC50:  35nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HD80PDPubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))TBA
LigandPNGBDBM455347(7-(3,3-Difluorocyclobutyl)-N4,5,5-trimethyl-N2-((1...)copy SMILEScopy InChI
Affinity DataEC50:  36nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μl in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27M0C0JUS Patent
TargetAmyloid-beta precursor protein(Homo sapiens (Human))TBA
LigandPNGBDBM455339(7-(4-Fluorophenyl)-N2-((1R,5S,8s)-3-(6-methoxypyri...)copy SMILEScopy InChI
Affinity DataEC50:  46nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μl in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27M0C0JUS Patent
TargetAmyloid-beta precursor protein(Homo sapiens (Human))TBA
LigandPNGBDBM455352(N2-((1R,5S,8s)-3-(6-Methoxypyridazin-4-yl)-3-azabi...)copy SMILEScopy InChI
Affinity DataEC50:  53nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μl in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27M0C0JUS Patent
TargetAmyloid-beta precursor protein(Homo sapiens (Human))TBA
LigandPNGBDBM50609115(CHEMBL2151085)copy SMILES
Affinity DataEC50:  70nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
TargetAmyloid-beta precursor protein(Homo sapiens (Human))TBA
LigandPNGBDBM28960((2R)-2-{[5-chloro-2-(hydroxymethyl)phenyl](4-chlor...)copy SMILEScopy InChI
Affinity DataEC50:  100nMAssay Description:In vitro effective concentration against beta amyloid protein 40 in ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N879B4PubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))TBA
LigandPNGBDBM455348(7-(3,3-Difluorocyclobutyl)-N4,5,5-trimethyl-N2-((1...)copy SMILEScopy InChI
Affinity DataEC50:  104nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μl in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27M0C0JUS Patent
TargetAmyloid-beta precursor protein(Homo sapiens (Human))TBA
LigandPNGBDBM455351(N4,5,5-Trimethyl-N2-((1R,5S,8s)-3-(6-methylpyrimid...)copy SMILEScopy InChI
Affinity DataEC50:  111nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μl in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27M0C0JUS Patent
TargetAmyloid-beta precursor protein(Homo sapiens (Human))TBA
LigandPNGBDBM50305469(CHEMBL590830 | N-(3-(2-amino-4-cyclohexyl-1-methyl...)copy SMILEScopy InChI
Affinity DataEC50:  180nMAssay Description:Inhibition of human recombinant APP expressed in CHO-K1 cells assessed as reduction of amyloid beta level by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20Z73BNPubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))TBA
LigandPNGBDBM50314993(2-(2-amino-6-((2-(2-chlorophenyl)-5-(4-(pyrimidin-...)copy SMILEScopy InChI
Affinity DataEC50:  190nMAssay Description:Inhibition of human recombinant APP in CHO cells assessed as decrease in beta amyloid protein level by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PG1RWSPubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))TBA
LigandPNGBDBM50609114(CHEMBL2151086)copy SMILES
Affinity DataEC50:  270nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
TargetAmyloid-beta precursor protein(Homo sapiens (Human))TBA
LigandPNGBDBM50314994(2-(2-amino-6-((2-(2-chlorophenyl)-5-(4-(pyrimidin-...)copy SMILEScopy InChI
Affinity DataEC50:  440nMAssay Description:Inhibition of human recombinant APP in CHO cells assessed as decrease in beta amyloid protein level by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PG1RWSPubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))TBA
LigandPNGBDBM50163996(4-(4-Chloro-benzenesulfonyl)-4-(2-methoxy-phenyl)-...)copy SMILEScopy InChI
Affinity DataEC50:  530nMAssay Description:In vitro reduction of Swedish NL mutant amyloid precursor protein activity expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N879B4PubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))TBA
LigandPNGBDBM50163996(4-(4-Chloro-benzenesulfonyl)-4-(2-methoxy-phenyl)-...)copy SMILEScopy InChI
Affinity DataEC50:  640nMAssay Description:In vitro elevation of beta C-terminal fragment (Ct-99) in CHO cells expressing mutant Swedish NL human APPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N879B4PubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))TBA
LigandPNGBDBM50305467(2-amino-4-cyclohexyl-1-methyl-4-phenyl-1H-imidazol...)copy SMILEScopy InChI
Affinity DataEC50:  810nMAssay Description:Inhibition of human recombinant APP expressed in CHO-K1 cells assessed as reduction of amyloid beta level by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20Z73BNPubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))TBA
LigandPNGBDBM50163996(4-(4-Chloro-benzenesulfonyl)-4-(2-methoxy-phenyl)-...)copy SMILEScopy InChI
Affinity DataEC50:  1.03E+3nMAssay Description:In vitro inhibition of amyloid precursor protein 695 activity in CHO cells expressing human APPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N879B4PubMed
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