Compile Data Set for Download or QSAR
Found 125 of ic50 data for polymerid = 2243,2244
TargetPurine nucleoside phosphorylase(Bos taurus (bovine))
BioCryst Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50046239(2-Amino-9-thiophen-3-ylmethyl-1,9-dihydro-purin-6-...)copy SMILEScopy InChI
Affinity DataIC50: 0.0670nMAssay Description:Inhibition of Purine nucleoside phosphorylase was evaluated against the enzyme from calf spleen in 1 mM phosphateMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B27TCXPubMed
TargetPurine nucleoside phosphorylase(Bos taurus (bovine))
BioCryst Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50046215(2,8-Diamino-9-thiophen-2-ylmethyl-1,9-dihydro-puri...)copy SMILEScopy InChI
Affinity DataIC50: 0.160nMAssay Description:Inhibition of purine nucleoside phosphorylase against the enzyme from calf spleen in 1 mM phosphateMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B27TCXPubMed
TargetPurine nucleoside phosphorylase(Bos taurus (bovine))
BioCryst Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50046229(2-Amino-6-pyridin-3-yl-3,7-dihydro-pyrrolo[3,2-d]p...)copy SMILEScopy InChI
Affinity DataIC50: 0.160nMAssay Description:Inhibition of Purine nucleoside phosphorylase was evaluated against the enzyme from calf spleen in 50 mM phosphateMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B27TCXPubMed
TargetPurine nucleoside phosphorylase(Bos taurus (bovine))
BioCryst Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50046238(2,8-Diamino-9-thiophen-3-ylmethyl-1,9-dihydro-puri...)copy SMILEScopy InChI
Affinity DataIC50: 0.630nMAssay Description:Inhibition of purine nucleoside phosphorylase against the enzyme from calf spleen in 1 mM phosphateMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B27TCXPubMed
TargetPurine nucleoside phosphorylase(Bos taurus (bovine))
BioCryst Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50214707(9-(5',5'-Difluoro-5'-phosphonopentyl)-9-deazaguani...)copy SMILEScopy InChI
Affinity DataIC50: 10.2nMAssay Description:Inhibition of calf PNP in presence of 1 mM phosphateMore data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Bos taurus (bovine))
BioCryst Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50214707(9-(5',5'-Difluoro-5'-phosphonopentyl)-9-deazaguani...)copy SMILEScopy InChI
Affinity DataIC50: 10.2nMAssay Description:Inhibition of calf spleen PNP assessed as inhibition of 25 uM 7-methylguanosine phosphorolysis by spectrophotometry in presence of 1 mM inorganic pho...More data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Bos taurus (bovine))
BioCryst Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50308521(9-[6',6'-Difluoro-6'-(diethylphosphono)hexyl]-9-de...)copy SMILEScopy InChI
Affinity DataIC50: 10.2nMAssay Description:Inhibition of calf spleen PNP assessed as inhibition of 25 uM 7-methylguanosine phosphorolysis by spectrophotometry in presence of 1 mM inorganic pho...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N58MG0PubMed
TargetPurine nucleoside phosphorylase(Bos taurus (bovine))
BioCryst Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50048044(2-Amino-7-(tetrahydro-thiophen-2-ylmethyl)-3,5-dih...)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:In vitro inhibition of purine nucleoside phosphorylase from calf spleen in 1 mM phosphateMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WQ02WDPubMed
TargetPurine nucleoside phosphorylase(Bos taurus (bovine))
BioCryst Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50046226(2-Amino-9-thiophen-2-ylmethyl-1,9-dihydro-purin-6-...)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of purine nucleoside phosphorylase against the enzyme from calf spleen in 1 mM phosphateMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B27TCXPubMed
TargetPurine nucleoside phosphorylase(Bos taurus (bovine))
BioCryst Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50048053(2-Amino-7-(3-trifluoromethyl-cyclohexylmethyl)-3,5...)copy SMILEScopy InChI
Affinity DataIC50: 14.8nMAssay Description:Inhibitory activity against calf spleen purine nucleoside phosphorylase (PNP) using inosine as substrate at a concentration of 10 uM.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CR5SKNPubMed
TargetPurine nucleoside phosphorylase(Bos taurus (bovine))
BioCryst Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50078454(2-Amino-7-pyridin-2-ylmethyl-3,5-dihydro-pyrrolo[3...)copy SMILEScopy InChI
Affinity DataIC50: 15.3nMAssay Description:Inhibitory activity against calf spleen purine nucleoside phosphorylase (PNP) using inosine as substrate at a concentration of 10 uM.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CR5SKNPubMed
TargetPurine nucleoside phosphorylase(Bos taurus (bovine))
BioCryst Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50039549(3-(2-Amino-4-oxo-4,5-dihydro-3H-pyrrolo[3,2-d]pyri...)copy SMILEScopy InChI
Affinity DataIC50: 16.3nMAssay Description:Inhibitory activity against calf spleen purine nucleoside phosphorylase (PNP) using inosine as substrate at a concentration of 10 uM.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CR5SKNPubMed
TargetPurine nucleoside phosphorylase(Bos taurus (bovine))
BioCryst Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50039547(2-Amino-7-benzyl-3,5-dihydro-pyrrolo[3,2-d]pyrimid...)copy SMILEScopy InChI
Affinity DataIC50: 16.5nMAssay Description:Inhibitory activity against calf spleen purine nucleoside phosphorylase (PNP) using inosine as substrate at a concentration of 10 uM.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CR5SKNPubMed
TargetPurine nucleoside phosphorylase(Bos taurus (bovine))
BioCryst Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50046225(2-Amino-7-(3,4-dichloro-benzyl)-3,5-dihydro-pyrrol...)copy SMILEScopy InChI
Affinity DataIC50: 17nMAssay Description:Inhibition of purine nucleoside phosphorylase against the enzyme from calf spleen in 1 mM phosphateMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B27TCXPubMed
TargetPurine nucleoside phosphorylase(Bos taurus (bovine))
BioCryst Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50046219(2-Amino-7-(4-chloro-benzyl)-3,5-dihydro-pyrrolo[3,...)copy SMILEScopy InChI
Affinity DataIC50: 17.4nMAssay Description:Inhibitory activity against calf spleen purine nucleoside phosphorylase (PNP) using inosine as substrate at a concentration of 10 uM.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CR5SKNPubMed
TargetPurine nucleoside phosphorylase(Bos taurus (bovine))
BioCryst Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50048044(2-Amino-7-(tetrahydro-thiophen-2-ylmethyl)-3,5-dih...)copy SMILEScopy InChI
Affinity DataIC50: 17.4nMAssay Description:Inhibitory activity against calf spleen purine nucleoside phosphorylase (PNP) using inosine as substrate at a concentration of 10 uM.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CR5SKNPubMed
TargetPurine nucleoside phosphorylase(Bos taurus (bovine))
BioCryst Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50048045(2-Amino-7-[1,2]dithian-3-ylmethyl-3,5-dihydro-pyrr...)copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:In vitro inhibition of purine nucleoside phosphorylase from calf spleen in 1 mM phosphateMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WQ02WDPubMed
TargetPurine nucleoside phosphorylase(Bos taurus (bovine))
BioCryst Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50214705(5-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-1,1-di...)copy SMILEScopy InChI
Affinity DataIC50: 18.7nMAssay Description:Inhibition of calf spleen PNP assessed as inhibition of 25 uM 7-methylguanosine phosphorolysis by spectrophotometry in presence of 1 mM inorganic pho...More data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Bos taurus (bovine))
BioCryst Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50214705(5-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-1,1-di...)copy SMILEScopy InChI
Affinity DataIC50: 18.7nMAssay Description:Inhibition of calf PNP in presence of 1 mM phosphateMore data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Bos taurus (bovine))
BioCryst Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50048046(2-Amino-7-(3-methyl-cyclohexylmethyl)-3,5-dihydro-...)copy SMILEScopy InChI
Affinity DataIC50: 19.2nMAssay Description:Inhibitory activity against calf spleen purine nucleoside phosphorylase (PNP) using inosine as substrate at a concentration of 10 uM.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CR5SKNPubMed
TargetPurine nucleoside phosphorylase(Bos taurus (bovine))
BioCryst Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50042804(2-Amino-7-(3-chloro-benzyl)-3,5-dihydro-pyrrolo[3,...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of Purine nucleoside phosphorylase was evaluated against the enzyme from calf spleen in 50 mM phosphateMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B27TCXPubMed
TargetPurine nucleoside phosphorylase(Bos taurus (bovine))
BioCryst Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50039562(2-Amino-7-cyclopentylmethyl-3,5-dihydro-pyrrolo[3,...)copy SMILEScopy InChI
Affinity DataIC50: 20.2nMAssay Description:Inhibitory activity against calf spleen purine nucleoside phosphorylase (PNP) using inosine as substrate at a concentration of 10 uM.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CR5SKNPubMed
TargetPurine nucleoside phosphorylase(Bos taurus (bovine))
BioCryst Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50046242(2-Amino-7-thiophen-2-ylmethyl-3,5-dihydro-pyrrolo[...)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:Inhibition of purine nucleoside phosphorylase against the enzyme from calf spleen in 1 mM phosphateMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B27TCXPubMed
TargetPurine nucleoside phosphorylase(Bos taurus (bovine))
BioCryst Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50042800(2-Amino-7-cyclohexylmethyl-3,5-dihydro-pyrrolo[3,2...)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:Inhibitory activity against calf spleen purine nucleoside phosphorylase (PNP) using inosine as substrate at a concentration of 10 uM.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CR5SKNPubMed
TargetPurine nucleoside phosphorylase(Bos taurus (bovine))
BioCryst Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50039544(2-Amino-7-thiophen-3-ylmethyl-3,5-dihydro-pyrrolo[...)copy SMILEScopy InChI
Affinity DataIC50: 22.6nMAssay Description:Inhibitory activity against calf spleen purine nucleoside phosphorylase (PNP) using inosine as substrate at a concentration of 10 uM.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CR5SKNPubMed
TargetPurine nucleoside phosphorylase(Bos taurus (bovine))
BioCryst Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50046245(2-Amino-7-(4-iodo-benzyl)-3,5-dihydro-pyrrolo[3,2-...)copy SMILEScopy InChI
Affinity DataIC50: 23nMAssay Description:Inhibition of Purine nucleoside phosphorylase was evaluated against the enzyme from calf spleen in 50 mM phosphateMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B27TCXPubMed
TargetPurine nucleoside phosphorylase(Bos taurus (bovine))
BioCryst Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50046233(2-Amino-7-(3-fluoro-benzyl)-3,5-dihydro-pyrrolo[3,...)copy SMILEScopy InChI
Affinity DataIC50: 24nMAssay Description:Inhibition of Purine nucleoside phosphorylase was evaluated against the enzyme from calf spleen in 1 mM phosphateMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B27TCXPubMed
TargetPurine nucleoside phosphorylase(Bos taurus (bovine))
BioCryst Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50039548(7-Benzyl-3,5-dihydro-pyrrolo[3,2-d]pyrimidin-4-one...)copy SMILEScopy InChI
Affinity DataIC50: 24.5nMAssay Description:Inhibitory activity against calf spleen purine nucleoside phosphorylase (PNP) using inosine as substrate at a concentration of 10 uM.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CR5SKNPubMed
TargetPurine nucleoside phosphorylase(Bos taurus (bovine))
BioCryst Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50039542(2-Amino-7-pyridin-3-ylmethyl-3,5-dihydro-pyrrolo[3...)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Inhibition of Purine nucleoside phosphorylase was evaluated against the enzyme from calf spleen in 50 mM phosphateMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B27TCXPubMed
TargetPurine nucleoside phosphorylase(Bos taurus (bovine))
BioCryst Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50046219(2-Amino-7-(4-chloro-benzyl)-3,5-dihydro-pyrrolo[3,...)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Inhibition of purine nucleoside phosphorylase against the enzyme from calf spleen in 1 mM phosphateMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B27TCXPubMed
TargetPurine nucleoside phosphorylase(Bos taurus (bovine))
BioCryst Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50048046(2-Amino-7-(3-methyl-cyclohexylmethyl)-3,5-dihydro-...)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:In vitro inhibition of purine nucleoside phosphorylase from calf spleen in 1 mM phosphateMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WQ02WDPubMed
TargetPurine nucleoside phosphorylase(Bos taurus (bovine))
BioCryst Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50048053(2-Amino-7-(3-trifluoromethyl-cyclohexylmethyl)-3,5...)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:In vitro inhibition of purine nucleoside phosphorylase from calf spleen in 1 mM phosphateMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WQ02WDPubMed
TargetPurine nucleoside phosphorylase(Bos taurus (bovine))
BioCryst Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50039544(2-Amino-7-thiophen-3-ylmethyl-3,5-dihydro-pyrrolo[...)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Inhibition of purine nucleoside phosphorylase against the enzyme from calf spleen in 1 mM phosphateMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B27TCXPubMed
TargetPurine nucleoside phosphorylase(Bos taurus (bovine))
BioCryst Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50042804(2-Amino-7-(3-chloro-benzyl)-3,5-dihydro-pyrrolo[3,...)copy SMILEScopy InChI
Affinity DataIC50: 25.8nMAssay Description:Inhibitory activity against calf spleen purine nucleoside phosphorylase (PNP) using inosine as substrate at a concentration of 10 uM.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CR5SKNPubMed
TargetPurine nucleoside phosphorylase(Bos taurus (bovine))
BioCryst Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50039542(2-Amino-7-pyridin-3-ylmethyl-3,5-dihydro-pyrrolo[3...)copy SMILEScopy InChI
Affinity DataIC50: 27nMAssay Description:Inhibitory activity against calf spleen purine nucleoside phosphorylase (PNP) using inosine as substrate at a concentration of 10 uM.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CR5SKNPubMed
TargetPurine nucleoside phosphorylase(Bos taurus (bovine))
BioCryst Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50039562(2-Amino-7-cyclopentylmethyl-3,5-dihydro-pyrrolo[3,...)copy SMILEScopy InChI
Affinity DataIC50: 29nMAssay Description:In vitro inhibition of purine nucleoside phosphorylase from calf spleen in 1 mM phosphateMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WQ02WDPubMed
TargetPurine nucleoside phosphorylase(Bos taurus (bovine))
BioCryst Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50048043(2-Amino-7-cycloheptylmethyl-3,5-dihydro-pyrrolo[3,...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:In vitro inhibition of purine nucleoside phosphorylase from calf spleen in 1 mM phosphateMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WQ02WDPubMed
TargetPurine nucleoside phosphorylase(Bos taurus (bovine))
BioCryst Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50078452((S)-3-(2-Amino-4-oxo-4,5-dihydro-3H-pyrrolo[3,2-d]...)copy SMILEScopy InChI
Affinity DataIC50: 35.6nMAssay Description:Inhibitory activity against calf spleen purine nucleoside phosphorylase (PNP) using inosine as substrate at a concentration of 10 uM.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CR5SKNPubMed
TargetPurine nucleoside phosphorylase(Bos taurus (bovine))
BioCryst Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50046232(2-Amino-7-(3-trifluoromethyl-benzyl)-3,5-dihydro-p...)copy SMILEScopy InChI
Affinity DataIC50: 36nMAssay Description:Inhibition of purine nucleoside phosphorylase against the enzyme from calf spleen in 1 mM phosphateMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B27TCXPubMed
TargetPurine nucleoside phosphorylase(Bos taurus (bovine))
BioCryst Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50046213(2-Amino-7-(3-hydroxy-benzyl)-3,5-dihydro-pyrrolo[3...)copy SMILEScopy InChI
Affinity DataIC50: 36.1nMAssay Description:Inhibitory activity against calf spleen purine nucleoside phosphorylase (PNP) using inosine as substrate at a concentration of 10 uM.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CR5SKNPubMed
TargetPurine nucleoside phosphorylase(Bos taurus (bovine))
BioCryst Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50078458(3-(4-Oxo-4,5-dihydro-3H-pyrrolo[3,2-d]pyrimidin-7-...)copy SMILEScopy InChI
Affinity DataIC50: 38.9nMAssay Description:Inhibitory activity against calf spleen purine nucleoside phosphorylase (PNP) using inosine as substrate at a concentration of 10 uM.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CR5SKNPubMed
TargetPurine nucleoside phosphorylase(Bos taurus (bovine))
BioCryst Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50078459(2-Amino-7-phenoxy-3,5-dihydro-pyrrolo[3,2-d]pyrimi...)copy SMILEScopy InChI
Affinity DataIC50: 41.5nMAssay Description:Inhibitory activity against calf spleen purine nucleoside phosphorylase (PNP) using inosine as substrate at a concentration of 10 uM.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CR5SKNPubMed
TargetPurine nucleoside phosphorylase(Bos taurus (bovine))
BioCryst Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50308522(9-[7',7'-Difluoro-7'-(diethylphosphono)heptyl]-9-d...)copy SMILEScopy InChI
Affinity DataIC50: 42nMAssay Description:Inhibition of calf spleen PNP assessed as inhibition of 25 uM 7-methylguanosine phosphorolysis by spectrophotometry in presence of 1 mM inorganic pho...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N58MG0PubMed
TargetPurine nucleoside phosphorylase(Bos taurus (bovine))
BioCryst Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50042799(3-(2-Amino-4-oxo-4,5-dihydro-3H-pyrrolo[3,2-d]pyri...)copy SMILEScopy InChI
Affinity DataIC50: 46.8nMAssay Description:Inhibitory activity against calf spleen purine nucleoside phosphorylase (PNP) using inosine as substrate at a concentration of 10 uM.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CR5SKNPubMed
TargetPurine nucleoside phosphorylase(Bos taurus (bovine))
BioCryst Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50042800(2-Amino-7-cyclohexylmethyl-3,5-dihydro-pyrrolo[3,2...)copy SMILEScopy InChI
Affinity DataIC50: 47nMAssay Description:In vitro inhibition of purine nucleoside phosphorylase from calf spleen in 1 mM phosphateMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WQ02WDPubMed
TargetPurine nucleoside phosphorylase(Bos taurus (bovine))
BioCryst Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50039547(2-Amino-7-benzyl-3,5-dihydro-pyrrolo[3,2-d]pyrimid...)copy SMILEScopy InChI
Affinity DataIC50: 51nMAssay Description:Inhibition of purine nucleoside phosphorylase against the enzyme from calf spleen in 1 mM phosphateMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B27TCXPubMed
TargetPurine nucleoside phosphorylase(Bos taurus (bovine))
BioCryst Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50046222(2-Amino-7-(3-methyl-benzyl)-3,5-dihydro-pyrrolo[3,...)copy SMILEScopy InChI
Affinity DataIC50: 57nMAssay Description:Inhibition of purine nucleoside phosphorylase against the enzyme from calf spleen in 1 mM phosphateMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B27TCXPubMed
TargetPurine nucleoside phosphorylase(Bos taurus (bovine))
BioCryst Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50280445((E)-2-{2-[(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl...)copy SMILEScopy InChI
Affinity DataIC50: 60nMAssay Description:Inhibitory concentration against calf spleen purine nucleoside phosphorylase in the presence of 50 mM (pi) orthophosphonateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WD412N
TargetPurine nucleoside phosphorylase(Bos taurus (bovine))
BioCryst Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50078453(2-Amino-7-pyridin-4-ylmethyl-3,5-dihydro-pyrrolo[3...)copy SMILEScopy InChI
Affinity DataIC50: 63.5nMAssay Description:Inhibitory activity against calf spleen purine nucleoside phosphorylase (PNP) using inosine as substrate at a concentration of 10 uM.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CR5SKNPubMed
TargetPurine nucleoside phosphorylase(Bos taurus (bovine))
BioCryst Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50005795(2,8-Diamino-9-thiophen-2-ylmethyl-1,9-dihydro-puri...)copy SMILEScopy InChI
Affinity DataIC50: 69.4nMAssay Description:Inhibitory activity against calf spleen purine nucleoside phosphorylase (PNP) using inosine as substrate at a concentration of 10 uM.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CR5SKNPubMed
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