Compile Data Set for Download or QSAR
Found 152 of ic50 data for polymerid = 50006345,50006987
TargetProtein-serine O-palmitoleoyltransferase porcupine(Homo sapiens (Human))
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50133864(CHEMBL2139947 | US10251893, Compound 59)copy SMILEScopy InChI
Affinity DataIC50: 0.0740nMAssay Description:Inhibition of porcupine activity (unknown origin) expressed in human HT1080 cells assessed as suppression of Wnt3A-mediated super top flash activity ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21838C2PubMed
TargetProtein-serine O-palmitoleoyltransferase porcupine(Mus musculus)
Genomics Institute of the Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM374968(US10251893, Cpd 166)copy SMILEScopy InChI
Affinity DataIC50: 0.100nMAssay Description:Inhibition of PORCN in mouse Leydig cells overexpressing Wnt3A co-cultured with TM3 cells transfected with Wnt-luciferase gene after 24 hrs by lumine...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB56F9PubMed
TargetProtein-serine O-palmitoleoyltransferase porcupine(Mus musculus)
Genomics Institute of the Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM374968(US10251893, Cpd 166)copy SMILEScopy InChI
Affinity DataIC50: 0.100nMAssay Description:Inhibition of PORCN in mouse Leydig cells overexpressing Wnt3A co-cultured with TM3 cells transfected with Wnt-luciferase gene after 24 hrs by lumine...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB56F9PubMed
TargetProtein-serine O-palmitoleoyltransferase porcupine(Homo sapiens (Human))
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50125819(CHEMBL3623895)copy SMILEScopy InChI
Affinity DataIC50: 0.110nMAssay Description:Inhibition of porcupine (unknown origin) expressed in mouse L Wnt3A cells co-cultured with TM3 cells harboring luciferase reporter gene assessed as r...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J10500PubMed
TargetProtein-serine O-palmitoleoyltransferase porcupine(Homo sapiens (Human))
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50125820(CHEMBL3623894)copy SMILEScopy InChI
Affinity DataIC50: 0.190nMAssay Description:Inhibition of porcupine (unknown origin) expressed in mouse L Wnt3A cells co-cultured with TM3 cells harboring luciferase reporter gene assessed as r...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J10500PubMed
TargetProtein-serine O-palmitoleoyltransferase porcupine(Mus musculus)
Genomics Institute of the Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM374847(US10251893, Cpd 51)copy SMILEScopy InChI
Affinity DataIC50: 0.200nMAssay Description:Inhibition of PORCN in mouse Leydig cells overexpressing Wnt3A co-cultured with TM3 cells transfected with Wnt-luciferase gene after 24 hrs by lumine...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB56F9PubMed
TargetProtein-serine O-palmitoleoyltransferase porcupine(Mus musculus)
Genomics Institute of the Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM374847(US10251893, Cpd 51)copy SMILEScopy InChI
Affinity DataIC50: 0.200nMAssay Description:Inhibition of PORCN in mouse Leydig cells overexpressing Wnt3A co-cultured with TM3 cells transfected with Wnt-luciferase gene after 24 hrs by lumine...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB56F9PubMed
TargetProtein-serine O-palmitoleoyltransferase porcupine(Mus musculus)
Genomics Institute of the Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM374846(US10251893, Cpd 50)copy SMILEScopy InChI
Affinity DataIC50: 0.200nMAssay Description:Inhibition of PORCN in mouse Leydig cells overexpressing Wnt3A co-cultured with TM3 cells transfected with Wnt-luciferase gene after 24 hrs by lumine...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB56F9PubMed
TargetProtein-serine O-palmitoleoyltransferase porcupine(Mus musculus)
Genomics Institute of the Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM375004(2-(2'-fluoro-3-methyl-2,4'-bipyridin-5-yl)-N-(5-(p...)copy SMILEScopy InChI
Affinity DataIC50: 0.200nMAssay Description:Inhibition of PORCN in mouse Leydig cells overexpressing Wnt3A co-cultured with TM3 cells transfected with Wnt-luciferase gene after 24 hrs by lumine...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB56F9PubMed
TargetProtein-serine O-palmitoleoyltransferase porcupine(Mus musculus)
Genomics Institute of the Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM374846(US10251893, Cpd 50)copy SMILEScopy InChI
Affinity DataIC50: 0.200nMAssay Description:Inhibition of PORCN in mouse Leydig cells overexpressing Wnt3A co-cultured with TM3 cells transfected with Wnt-luciferase gene after 24 hrs by lumine...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB56F9PubMed
TargetProtein-serine O-palmitoleoyltransferase porcupine(Mus musculus)
Genomics Institute of the Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM375004(2-(2'-fluoro-3-methyl-2,4'-bipyridin-5-yl)-N-(5-(p...)copy SMILEScopy InChI
Affinity DataIC50: 0.200nMAssay Description:Inhibition of PORCN in mouse Leydig cells overexpressing Wnt3A co-cultured with TM3 cells transfected with Wnt-luciferase gene after 24 hrs by lumine...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB56F9PubMed
TargetProtein-serine O-palmitoleoyltransferase porcupine(Homo sapiens (Human))
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50125941(CHEMBL3623875)copy SMILEScopy InChI
Affinity DataIC50: 0.230nMAssay Description:Inhibition of porcupine (unknown origin) expressed in mouse L Wnt3A cells co-cultured with TM3 cells harboring luciferase reporter gene assessed as r...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J10500PubMed
TargetProtein-serine O-palmitoleoyltransferase porcupine(Homo sapiens (Human))
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50125818(CHEMBL3623896)copy SMILEScopy InChI
Affinity DataIC50: 0.380nMAssay Description:Inhibition of porcupine (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J10500PubMed
TargetProtein-serine O-palmitoleoyltransferase porcupine(Mus musculus)
Genomics Institute of the Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50133870(CHEBI:78030 | CHEMBL3188386 | US10251893, Compound...)copy SMILEScopy InChI
Affinity DataIC50: 0.400nMAssay Description:Inhibition of PORCN in mouse Leydig cells overexpressing Wnt3A co-cultured with TM3 cells transfected with Wnt-luciferase gene after 24 hrs by lumine...More data for this Ligand-Target Pair
TargetProtein-serine O-palmitoleoyltransferase porcupine(Homo sapiens (Human))
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50133870(CHEBI:78030 | CHEMBL3188386 | US10251893, Compound...)copy SMILEScopy InChI
Affinity DataIC50: 0.400nMAssay Description:Inhibition of porcupine (unknown origin)More data for this Ligand-Target Pair
TargetProtein-serine O-palmitoleoyltransferase porcupine(Mus musculus)
Genomics Institute of the Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM374920(US10251893, Cpd 128)copy SMILEScopy InChI
Affinity DataIC50: 0.400nMAssay Description:Inhibition of PORCN in mouse Leydig cells overexpressing Wnt3A co-cultured with TM3 cells transfected with Wnt-luciferase gene after 24 hrs by lumine...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB56F9PubMed
TargetProtein-serine O-palmitoleoyltransferase porcupine(Mus musculus)
Genomics Institute of the Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM374916(N-(2,3'-bipyridin-6'-yl)-2-(2',3-dimethyl-2,4'-bip...)copy SMILEScopy InChI
Affinity DataIC50: 0.400nMAssay Description:Inhibition of PORCN in mouse Leydig cells overexpressing Wnt3A co-cultured with TM3 cells transfected with Wnt-luciferase gene after 24 hrs by lumine...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB56F9PubMed
TargetProtein-serine O-palmitoleoyltransferase porcupine(Mus musculus)
Genomics Institute of the Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50133870(CHEBI:78030 | CHEMBL3188386 | US10251893, Compound...)copy SMILEScopy InChI
Affinity DataIC50: 0.400nMAssay Description:Inhibition of PORCN in mouse Leydig cells overexpressing Wnt3A co-cultured with TM3 cells transfected with Wnt-luciferase gene after 24 hrs by lumine...More data for this Ligand-Target Pair
TargetProtein-serine O-palmitoleoyltransferase porcupine(Mus musculus)
Genomics Institute of the Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM374916(N-(2,3'-bipyridin-6'-yl)-2-(2',3-dimethyl-2,4'-bip...)copy SMILEScopy InChI
Affinity DataIC50: 0.400nMAssay Description:Inhibition of PORCN in mouse Leydig cells overexpressing Wnt3A co-cultured with TM3 cells transfected with Wnt-luciferase gene after 24 hrs by lumine...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB56F9PubMed
TargetProtein-serine O-palmitoleoyltransferase porcupine(Homo sapiens (Human))
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50133870(CHEBI:78030 | CHEMBL3188386 | US10251893, Compound...)copy SMILEScopy InChI
Affinity DataIC50: 0.400nMAssay Description:Inhibition of porcupine activity (unknown origin) expressed in human HT1080 cells assessed as suppression of Wnt3A-mediated super top flash activity ...More data for this Ligand-Target Pair
TargetProtein-serine O-palmitoleoyltransferase porcupine(Homo sapiens (Human))
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50257135(CHEMBL4080208)copy SMILEScopy InChI
Affinity DataIC50: 0.400nMAssay Description:Inhibition of porcupine (unknown origin) expressed in HEK293 cells after day 1 post treatment by Super-top flash reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2571FF5PubMed
TargetProtein-serine O-palmitoleoyltransferase porcupine(Mus musculus)
Genomics Institute of the Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM374920(US10251893, Cpd 128)copy SMILEScopy InChI
Affinity DataIC50: 0.400nMAssay Description:Inhibition of PORCN in mouse Leydig cells overexpressing Wnt3A co-cultured with TM3 cells transfected with Wnt-luciferase gene after 24 hrs by lumine...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB56F9PubMed
TargetProtein-serine O-palmitoleoyltransferase porcupine(Mus musculus)
Genomics Institute of the Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50197277(CHEMBL3972086)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMAssay Description:Inhibition of porcupine in mouse L Wnt3A cells co-cultured with HEK293 cells after 48 hrs by Super-top flash reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HQ41VNPubMed
TargetProtein-serine O-palmitoleoyltransferase porcupine(Homo sapiens (Human))
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50133865(CHEMBL3633801)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMAssay Description:Inhibition of porcupine in human HEK293 cells assessed as reduction in Wnt secretion by measuring suppression of beta-catenin reporter activity after...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21838C2PubMed
TargetProtein-serine O-palmitoleoyltransferase porcupine(Mus musculus)
Genomics Institute of the Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM374918(US10251893, Cpd 126)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMAssay Description:Inhibition of PORCN in mouse Leydig cells overexpressing Wnt3A co-cultured with TM3 cells transfected with Wnt-luciferase gene after 24 hrs by lumine...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB56F9PubMed
TargetProtein-serine O-palmitoleoyltransferase porcupine(Mus musculus)
Genomics Institute of the Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM374918(US10251893, Cpd 126)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMAssay Description:Inhibition of PORCN in mouse Leydig cells overexpressing Wnt3A co-cultured with TM3 cells transfected with Wnt-luciferase gene after 24 hrs by lumine...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB56F9PubMed
TargetProtein-serine O-palmitoleoyltransferase porcupine(Mus musculus)
Genomics Institute of the Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM374802(US10251893, Cpd 6)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMAssay Description:Inhibition of PORCN in mouse Leydig cells overexpressing Wnt3A co-cultured with TM3 cells transfected with Wnt-luciferase gene after 24 hrs by lumine...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB56F9PubMed
TargetProtein-serine O-palmitoleoyltransferase porcupine(Mus musculus)
Genomics Institute of the Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM374802(US10251893, Cpd 6)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMAssay Description:Inhibition of PORCN in mouse Leydig cells overexpressing Wnt3A co-cultured with TM3 cells transfected with Wnt-luciferase gene after 24 hrs by lumine...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB56F9PubMed
TargetProtein-serine O-palmitoleoyltransferase porcupine(Homo sapiens (Human))
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50125824(CHEMBL3623893)copy SMILEScopy InChI
Affinity DataIC50: 0.530nMAssay Description:Inhibition of porcupine (unknown origin) expressed in mouse L Wnt3A cells co-cultured with TM3 cells harboring luciferase reporter gene assessed as r...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J10500PubMed
TargetProtein-serine O-palmitoleoyltransferase porcupine(Homo sapiens (Human))
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50125818(CHEMBL3623896)copy SMILEScopy InChI
Affinity DataIC50: 0.570nMAssay Description:Inhibition of porcupine (unknown origin) expressed in mouse L Wnt3A cells co-cultured with TM3 cells harboring luciferase reporter gene assessed as r...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J10500PubMed
TargetProtein-serine O-palmitoleoyltransferase porcupine(Homo sapiens (Human))
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50125825(CHEMBL3623892)copy SMILEScopy InChI
Affinity DataIC50: 0.670nMAssay Description:Inhibition of porcupine (unknown origin) expressed in mouse L Wnt3A cells co-cultured with TM3 cells harboring luciferase reporter gene assessed as r...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J10500PubMed
TargetProtein-serine O-palmitoleoyltransferase porcupine(Mus musculus)
Genomics Institute of the Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM374822(2-(4-(2-methylpyridin-4-yl)phenyl)-N-(5-phenylpyri...)copy SMILEScopy InChI
Affinity DataIC50: 0.700nMAssay Description:Inhibition of PORCN in mouse Leydig cells overexpressing Wnt3A co-cultured with TM3 cells transfected with Wnt-luciferase gene after 24 hrs by lumine...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB56F9PubMed
TargetProtein-serine O-palmitoleoyltransferase porcupine(Mus musculus)
Genomics Institute of the Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM374948(N-(5-(4-acetylpiperazin-1-yl)pyridin-2-yl)-2-(2',3...)copy SMILEScopy InChI
Affinity DataIC50: 0.700nMAssay Description:Inhibition of PORCN in mouse Leydig cells overexpressing Wnt3A co-cultured with TM3 cells transfected with Wnt-luciferase gene after 24 hrs by lumine...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB56F9PubMed
TargetProtein-serine O-palmitoleoyltransferase porcupine(Mus musculus)
Genomics Institute of the Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM374822(2-(4-(2-methylpyridin-4-yl)phenyl)-N-(5-phenylpyri...)copy SMILEScopy InChI
Affinity DataIC50: 0.700nMAssay Description:Inhibition of PORCN in mouse Leydig cells overexpressing Wnt3A co-cultured with TM3 cells transfected with Wnt-luciferase gene after 24 hrs by lumine...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB56F9PubMed
TargetProtein-serine O-palmitoleoyltransferase porcupine(Mus musculus)
Genomics Institute of the Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM374948(N-(5-(4-acetylpiperazin-1-yl)pyridin-2-yl)-2-(2',3...)copy SMILEScopy InChI
Affinity DataIC50: 0.700nMAssay Description:Inhibition of PORCN in mouse Leydig cells overexpressing Wnt3A co-cultured with TM3 cells transfected with Wnt-luciferase gene after 24 hrs by lumine...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB56F9PubMed
TargetProtein-serine O-palmitoleoyltransferase porcupine(Mus musculus)
Genomics Institute of the Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50458259(CHEMBL4215992)copy SMILEScopy InChI
Affinity DataIC50: 0.720nMAssay Description:Inhibition of porcupine in mouse L Wnt3A cells co-cultured with HEK293 cells assessed as suppression of Wnt signaling after 48 hrs by Super-top flash...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR7ZMQPubMed
TargetProtein-serine O-palmitoleoyltransferase porcupine(Mus musculus)
Genomics Institute of the Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM374998(N-(5-(4-acetylpiperazin-1-yl)pyridin-2-yl)-2-(2'-f...)copy SMILEScopy InChI
Affinity DataIC50: 0.800nMAssay Description:Inhibition of PORCN in mouse Leydig cells overexpressing Wnt3A co-cultured with TM3 cells transfected with Wnt-luciferase gene after 24 hrs by lumine...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB56F9PubMed
TargetProtein-serine O-palmitoleoyltransferase porcupine(Mus musculus)
Genomics Institute of the Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM374998(N-(5-(4-acetylpiperazin-1-yl)pyridin-2-yl)-2-(2'-f...)copy SMILEScopy InChI
Affinity DataIC50: 0.800nMAssay Description:Inhibition of PORCN in mouse Leydig cells overexpressing Wnt3A co-cultured with TM3 cells transfected with Wnt-luciferase gene after 24 hrs by lumine...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB56F9PubMed
TargetProtein-serine O-palmitoleoyltransferase porcupine(Mus musculus)
Genomics Institute of the Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50133870(CHEBI:78030 | CHEMBL3188386 | US10251893, Compound...)copy SMILEScopy InChI
Affinity DataIC50: 0.900nMAssay Description:Inhibition of porcupine in mouse L Wnt3A cells co-cultured with HEK293 cells after 48 hrs by Super-top flash reporter gene assayMore data for this Ligand-Target Pair
TargetProtein-serine O-palmitoleoyltransferase porcupine(Mus musculus)
Genomics Institute of the Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50133870(CHEBI:78030 | CHEMBL3188386 | US10251893, Compound...)copy SMILEScopy InChI
Affinity DataIC50: 0.900nMAssay Description:Inhibition of porcupine in mouse L Wnt3A cells co-cultured with HEK293 cells assessed as suppression of Wnt signaling after 48 hrs by Super-top flash...More data for this Ligand-Target Pair
TargetProtein-serine O-palmitoleoyltransferase porcupine(Homo sapiens (Human))
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50125826(CHEMBL3623891)copy SMILEScopy InChI
Affinity DataIC50: 0.960nMAssay Description:Inhibition of porcupine (unknown origin) expressed in mouse L Wnt3A cells co-cultured with TM3 cells harboring luciferase reporter gene assessed as r...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J10500PubMed
TargetProtein-serine O-palmitoleoyltransferase porcupine(Homo sapiens (Human))
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50233628(CHEMBL4088716)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of porcupine (unknown origin) expressed in HEK293-STF3A cells assessed as inhibition of Wnt signaling by measuring decrease in beta-cateni...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29K4DG1PubMed
TargetProtein-serine O-palmitoleoyltransferase porcupine(Mus musculus)
Genomics Institute of the Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50197194(CHEMBL3907027)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of porcupine in mouse L Wnt3A cells co-cultured with HEK293 cells after 48 hrs by Super-top flash reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HQ41VNPubMed
TargetProtein-serine O-palmitoleoyltransferase porcupine(Homo sapiens (Human))
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50133864(CHEMBL2139947 | US10251893, Compound 59)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of porcupine in HEK293T cells transfected with Wnt3A-expressing vector assessed as suppression of Wnt/beta-catenin signaling after 22 hrs ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GX4F5DPubMed
TargetProtein-serine O-palmitoleoyltransferase porcupine(Homo sapiens (Human))
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50257160(CHEMBL4096728)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of porcupine (unknown origin) expressed in HEK293 cells after day 1 post treatment by Super-top flash reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2571FF5PubMed
TargetProtein-serine O-palmitoleoyltransferase porcupine(Homo sapiens (Human))
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50257143(CHEMBL4080021)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of porcupine (unknown origin) expressed in HEK293 cells after day 1 post treatment by Super-top flash reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2571FF5PubMed
TargetProtein-serine O-palmitoleoyltransferase porcupine(Homo sapiens (Human))
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50233629(CHEMBL4080842)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of porcupine (unknown origin) expressed in HEK293-STF3A cells assessed as inhibition of Wnt signaling by measuring decrease in beta-cateni...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29K4DG1PubMed
TargetProtein-serine O-palmitoleoyltransferase porcupine(Mus musculus)
Genomics Institute of the Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50458258(CHEMBL4215124)copy SMILEScopy InChI
Affinity DataIC50: 1.90nMAssay Description:Inhibition of porcupine in mouse L Wnt3A cells co-cultured with HEK293 cells assessed as suppression of Wnt signaling after 48 hrs by Super-top flash...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR7ZMQPubMed
TargetProtein-serine O-palmitoleoyltransferase porcupine(Mus musculus)
Genomics Institute of the Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM374798(N-(6-methoxybenzo [d]thiazol-2-yl)-2-(4-(pyridin-4...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of PORCN in mouse Leydig cells overexpressing Wnt3A co-cultured with TM3 cells transfected with Wnt-luciferase gene after 24 hrs by lumine...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB56F9PubMed
TargetProtein-serine O-palmitoleoyltransferase porcupine(Homo sapiens (Human))
Experimental Therapeutics Centre

Curated by ChEMBL
LigandPNGBDBM50233636(CHEMBL4070649)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of porcupine (unknown origin) expressed in HEK293-STF3A cells assessed as inhibition of Wnt signaling by measuring decrease in beta-cateni...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29K4DG1PubMed
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