Compile Data Set for Download or QSAR
Found 38 of ki data for polymerid = 49000514
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
Wyeth Research

Curated by PDSP Ki Database
LigandPNGBDBM86712(CAS_868359-05-1 | N-[4-(2-BROMO-4,5-DIFLUOROPHENOX...)copy SMILEScopy InChI
Affinity DataKi:  85nMMore data for this Ligand-Target Pair
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
Wyeth Research

Curated by PDSP Ki Database
LigandPNGBDBM86713(WAY 213394 | WAY-213394)copy SMILEScopy InChI
Affinity DataKi:  145nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G44NVXPubMed
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
Wyeth Research

Curated by PDSP Ki Database
LigandPNGBDBM86714(WAY 212922 | WAY-212922)copy SMILEScopy InChI
Affinity DataKi:  157nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G44NVXPubMed
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
Wyeth Research

Curated by PDSP Ki Database
LigandPNGBDBM86711(3-[3-Methyl-4-(4-chlorophenyl)benzoylamino]alanine...)copy SMILEScopy InChI
Affinity DataKi:  190nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G44NVXPubMed
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
Wyeth Research

Curated by PDSP Ki Database
LigandPNGBDBM86058(MCL0129)copy SMILEScopy InChI
Affinity DataKi:  1.00E+3nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FQ9V5WPubMed
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
Wyeth Research

Curated by PDSP Ki Database
LigandPNGBDBM50327886((1R,2S,5S,6S)-3-azabicyclo[3.1.0]hexane-2,6-dicarb...)copy SMILEScopy InChI
Affinity DataKi:  1.60E+3nMAssay Description:Inhibition of human GLT1 expressed in Xenopus laevis Oocytes assessed as reduction of [3H]-glutamate uptake after 10 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27081NRPubMed
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
Wyeth Research

Curated by PDSP Ki Database
LigandPNGBDBM86316(WAY-855)copy SMILEScopy InChI
Affinity DataKi:  2.20E+3nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HD7T74PubMed
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
Wyeth Research

Curated by PDSP Ki Database
LigandPNGBDBM86317(WAY-865)copy SMILEScopy InChI
Affinity DataKi:  2.57E+3nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HD7T74PubMed
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
Wyeth Research

Curated by PDSP Ki Database
LigandPNGBDBM86316(WAY-855)copy SMILEScopy InChI
Affinity DataKi:  2.57E+3nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HD7T74PubMed
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
Wyeth Research

Curated by PDSP Ki Database
LigandPNGBDBM50197103((2S,1'R,2'S)-2-(2'-Carboxycyclobutyl)glycine | CHE...)copy SMILEScopy InChI
Affinity DataKi:  6.60E+3nMAssay Description:Inhibition of human EAAT2 expressed in HEK293 cells by FLIPR membrane potential assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S46RMKPubMed
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
Wyeth Research

Curated by PDSP Ki Database
LigandPNGBDBM50197105((2S,1'S,2'R)-2-(2'-Carboxycyclobutyl)glycine | CHE...)copy SMILEScopy InChI
Affinity DataKi:  6.60E+3nMAssay Description:Inhibition of human GLT1 expressed in Xenopus laevis Oocytes assessed as reduction of [3H]-glutamate uptake after 10 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27081NRPubMed
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
Wyeth Research

Curated by PDSP Ki Database
LigandPNGBDBM86315(WAY-879)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HD7T74PubMed
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
Wyeth Research

Curated by PDSP Ki Database
LigandPNGBDBM50327885((2S,3S)-pyrrolidine-2,3-dicarboxylic acid | CHEMBL...)copy SMILEScopy InChI
Affinity DataKi:  1.20E+4nMAssay Description:Inhibition of human GLT1 expressed in Xenopus laevis Oocytes assessed as reduction of [3H]-glutamate uptake after 10 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27081NRPubMed
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
Wyeth Research

Curated by PDSP Ki Database
LigandPNGBDBM50031704((2S,4R)-2-Amino-4-methyl-pentanedioic acid | (2S,4...)copy SMILEScopy InChI
Affinity DataKi:  1.30E+4nMAssay Description:Binding affinity to human EAAT2 expressed in HEK293 cells in FMP (FLPR) assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP52V1PubMed
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
Wyeth Research

Curated by PDSP Ki Database
LigandPNGBDBM50178684((2S,4R)-4-ethylglutamic acid | CHEMBL372124)copy SMILEScopy InChI
Affinity DataKi:  1.40E+4nMAssay Description:Binding affinity to human EAAT2 expressed in HEK293 cells in FMP (FLPR) assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP52V1PubMed
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
Wyeth Research

Curated by PDSP Ki Database
LigandPNGBDBM50178683((2S,4S)-4-isopropylglutamic acid | CHEMBL199564)copy SMILEScopy InChI
Affinity DataKi:  1.90E+4nMAssay Description:Binding affinity to human EAAT2 expressed in HEK293 cells in FMP (FLPR) assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP52V1PubMed
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
Wyeth Research

Curated by PDSP Ki Database
LigandPNGBDBM50178687((2S,4R)-4-isobutylglutamic acid | CHEMBL199617)copy SMILEScopy InChI
Affinity DataKi:  2.20E+4nMAssay Description:Binding affinity to human EAAT2 expressed in HEK293 cells in FMP (FLPR) assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP52V1PubMed
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
Wyeth Research

Curated by PDSP Ki Database
LigandPNGBDBM50197104((2S,1'R,2'R)-2-(2'-Carboxycyclobutyl)glycine | CHE...)copy SMILEScopy InChI
Affinity DataKi:  2.20E+4nMAssay Description:Inhibition of human EAAT2 expressed in HEK293 cells by FLIPR membrane potential assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S46RMKPubMed
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
Wyeth Research

Curated by PDSP Ki Database
LigandPNGBDBM50088230((2S,4R)-4-propylglutamic acid | 2-Amino-4-propyl-p...)copy SMILEScopy InChI
Affinity DataKi:  2.20E+4nMAssay Description:Binding affinity to human EAAT2 expressed in HEK293 cells in FMP (FLPR) assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP52V1PubMed
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
Wyeth Research

Curated by PDSP Ki Database
LigandPNGBDBM50178686((2S,4R)-4-isopentylglutamic acid | CHEMBL197176)copy SMILEScopy InChI
Affinity DataKi:  2.60E+4nMAssay Description:Binding affinity to human EAAT2 expressed in HEK293 cells in FMP (FLPR) assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP52V1PubMed
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
Wyeth Research

Curated by PDSP Ki Database
LigandPNGBDBM50178688((2S,4R)-4-benzylglutamic acid | CHEMBL198618)copy SMILEScopy InChI
Affinity DataKi:  3.60E+4nMAssay Description:Binding affinity to human EAAT2 expressed in HEK293 cells in FMP (FLPR) assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP52V1PubMed
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
Wyeth Research

Curated by PDSP Ki Database
LigandPNGBDBM50178685((2S,4R)-4-butylglutamic acid | CHEMBL381004)copy SMILEScopy InChI
Affinity DataKi:  4.20E+4nMAssay Description:Binding affinity to human EAAT2 expressed in HEK293 cells in FMP (FLPR) assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP52V1PubMed
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
Wyeth Research

Curated by PDSP Ki Database
LigandPNGBDBM50180145((1R,4S,5R,6S)-3-azabicyclo[3.3.0]octane-4,6-dicarb...)copy SMILEScopy InChI
Affinity DataKi:  5.20E+4nMAssay Description:Activity against human EAAT2 transfected in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GM86WBPubMed
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
Wyeth Research

Curated by PDSP Ki Database
LigandPNGBDBM50180145((1R,4S,5R,6S)-3-azabicyclo[3.3.0]octane-4,6-dicarb...)copy SMILEScopy InChI
Affinity DataKi:  5.20E+4nMAssay Description:Inhibition of human GLT1 expressed in Xenopus laevis Oocytes assessed as reduction of [3H]-glutamate uptake after 10 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27081NRPubMed
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
Wyeth Research

Curated by PDSP Ki Database
LigandPNGBDBM17657((2S)-2-aminopentanedioic acid | (S)-Glu | D-Glutam...)copy SMILEScopy InChI
Affinity DataKi:  6.20E+4nMAssay Description:Inhibition of [3H]D-Asp uptake at human EAAT2 in HEK293 cellsChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M95FCPubMed
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
Wyeth Research

Curated by PDSP Ki Database
LigandPNGBDBM50088220((2S,4R)-4-pentylglutamic acid | 2-Amino-4-pentyl-p...)copy SMILEScopy InChI
Affinity DataKi:  7.70E+4nMAssay Description:Binding affinity to human EAAT2 expressed in HEK293 cells in FMP (FLPR) assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP52V1PubMed
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
Wyeth Research

Curated by PDSP Ki Database
LigandPNGBDBM50251894((2S,4R)-4-(2,2-Diphenylethylamino-3-oxopropyl)glut...)copy SMILEScopy InChI
Affinity DataKi:  9.50E+4nMAssay Description:Inhibition of [3H]D-Asp uptake at human EAAT2 in HEK293 cellsChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M95FCPubMed
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
Wyeth Research

Curated by PDSP Ki Database
LigandPNGBDBM50197105((2S,1'S,2'R)-2-(2'-Carboxycyclobutyl)glycine | CHE...)copy SMILEScopy InChI
Affinity DataKi:  1.10E+5nMAssay Description:Inhibition of human EAAT2 expressed in HEK293 cells by FLIPR membrane potential assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S46RMKPubMed
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
Wyeth Research

Curated by PDSP Ki Database
LigandPNGBDBM50251951((2S,4S)-2-amino-4-(hydroxymethyl)pentanedioic acid...)copy SMILEScopy InChI
Affinity DataKi:  1.40E+5nMAssay Description:Inhibition of [3H]D-Asp uptake at human EAAT2 in HEK293 cellsChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M95FCPubMed
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
Wyeth Research

Curated by PDSP Ki Database
LigandPNGBDBM50252048((2S,4R)-2-amino-4-(3-methoxy-3-oxopropyl)pentanedi...)copy SMILEScopy InChI
Affinity DataKi:  1.80E+5nMAssay Description:Inhibition of [3H]D-Asp uptake at human EAAT2 in HEK293 cellsChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M95FCPubMed
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
Wyeth Research

Curated by PDSP Ki Database
LigandPNGBDBM50252046((2S,4S)-2-amino-4-(benzyloxymethyl)pentanedioic ac...)copy SMILEScopy InChI
Affinity DataKi:  2.90E+5nMAssay Description:Inhibition of [3H]D-Asp uptake at human EAAT2 in HEK293 cellsChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M95FCPubMed
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
Wyeth Research

Curated by PDSP Ki Database
LigandPNGBDBM50252050((2S,4R)-2-amino-4-(3-amino-3-oxopropyl)pentanedioi...)copy SMILEScopy InChI
Affinity DataKi:  2.90E+5nMAssay Description:Inhibition of [3H]D-Asp uptake at human EAAT2 in HEK293 cellsChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M95FCPubMed
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
Wyeth Research

Curated by PDSP Ki Database
LigandPNGBDBM50180146((3S,5S)-2-aza-bicyclo[2.2.1]heptane-3,5-dicarboxyl...)copy SMILEScopy InChI
Affinity DataKi: >4.00E+5nMAssay Description:Activity against human EAAT2 transfected in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GM86WBPubMed
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
Wyeth Research

Curated by PDSP Ki Database
LigandPNGBDBM50251893((2S,4R)-2-amino-4-(3-(benzylamino)-3-oxopropyl)pen...)copy SMILEScopy InChI
Affinity DataKi:  4.10E+5nMAssay Description:Inhibition of [3H]D-Asp uptake at human EAAT2 in HEK293 cellsChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M95FCPubMed
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
Wyeth Research

Curated by PDSP Ki Database
LigandPNGBDBM50252051((2S,4R)-2-amino-4-(3-(methylamino)-3-oxopropyl)pen...)copy SMILEScopy InChI
Affinity DataKi:  6.80E+5nMAssay Description:Inhibition of [3H]D-Asp uptake at human EAAT2 in HEK293 cellsChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M95FCPubMed
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
Wyeth Research

Curated by PDSP Ki Database
LigandPNGBDBM50252662((2S,4R)-4-(3-Propylamino-3-oxopropyl)glutamic acid...)copy SMILEScopy InChI
Affinity DataKi:  1.00E+6nMAssay Description:Inhibition of [3H]D-Asp uptake at human EAAT2 in HEK293 cellsChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M95FCPubMed
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
Wyeth Research

Curated by PDSP Ki Database
LigandPNGBDBM50252049((1S,3R)-1-aminopentane-1,3,5-tricarboxylic acid | ...)copy SMILEScopy InChI
Affinity DataKi: >3.00E+6nMAssay Description:Inhibition of [3H]D-Asp uptake at human EAAT2 in HEK293 cellsChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M95FCPubMed
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
Wyeth Research

Curated by PDSP Ki Database
LigandPNGBDBM50252047((2S,4S)-4-(2-Hydroxy-2-oxoethyl)glutamic Acid | (2...)copy SMILEScopy InChI
Affinity DataKi: >3.00E+6nMAssay Description:Inhibition of [3H]D-Asp uptake at human EAAT2 in HEK293 cellsChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M95FCPubMed