Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Prostaglandin G/H synthase 1 (Mus musculus) | BDBM11639 (4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PubMed | n/a | n/a | 0.700 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherche Servier Curated by ChEMBL | Assay Description Tested for inhibition against Prostaglandin G/H synthase 2 from mouse resident macrophages | J Med Chem 43: 4582-93 (2001) BindingDB Entry DOI: 10.7270/Q23B60T1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 1 (Mus musculus) | BDBM17638 (2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Università "La Sapienza" Curated by ChEMBL | Assay Description In vitro inhibitory activity against Prostaglandin G/H synthase 1 in murine J774 cells | J Med Chem 48: 3428-32 (2005) Article DOI: 10.1021/jm049121q BindingDB Entry DOI: 10.7270/Q2N01628 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 1 (Mus musculus) | BDBM50474760 (CG-100649 | CG100649 | Polmacoxib) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem | Article PubMed | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
The M.S University of Baroda Curated by ChEMBL | Assay Description Inhibition of COX-1 in LPS-induced mouse peritoneal macrophages | Eur J Med Chem 162: 1-17 (2019) Article DOI: 10.1016/j.ejmech.2018.10.054 BindingDB Entry DOI: 10.7270/Q2FX7DSW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 1/2 (Mus musculus-Mus musculus (Mouse)) | BDBM50229760 (CHEMBL316184 | WAY-121520) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth-Ayerst Research Curated by ChEMBL | Assay Description The compound was tested for inhibitory activity against Prostaglandin G/H synthase in mouse macrophage | J Med Chem 35: 2501-24 (1992) BindingDB Entry DOI: 10.7270/Q23B60R4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 1 (Mus musculus) | BDBM50474774 (CHEMBL352430) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 71.2 | n/a | n/a | n/a | n/a | n/a | n/a |
AmorePacific R&D Center Curated by ChEMBL | Assay Description In vitro inhibitory activity against prostaglandin G/H synthase 1 using mouse peritoneal macrophage method | J Med Chem 47: 792-804 (2004) Article DOI: 10.1021/jm020545z BindingDB Entry DOI: 10.7270/Q2QZ2DPG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 1 (Mus musculus) | BDBM50293280 (3-(4-(hydroxymethyl)phenyl)-4-(4-(methylsulfonyl)p...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 87 | n/a | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Medical Sciences Curated by ChEMBL | Assay Description Inhibition of COX1 in mouse peritoneal macrophages | Bioorg Med Chem Lett 19: 2270-2 (2009) Article DOI: 10.1016/j.bmcl.2009.02.090 BindingDB Entry DOI: 10.7270/Q2CF9PZR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 1 (Mus musculus) | BDBM50094558 (3,5-Diphenyl-4-aza-tricyclo[5.2.1.0*2,6*]deca-2,5-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherche Servier Curated by ChEMBL | Assay Description Inhibition against prostaglandin G/H synthase 1 from mouse resident macrophages | J Med Chem 43: 4582-93 (2001) BindingDB Entry DOI: 10.7270/Q23B60T1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 1 (Mus musculus) | BDBM50094555 (5,6-Dimethyl-1,3-diphenyl-4,7-dihydro-2H-isoindole...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | >100 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherche Servier Curated by ChEMBL | Assay Description Inhibition against prostaglandin G/H synthase 1 from mouse resident macrophages | J Med Chem 43: 4582-93 (2001) BindingDB Entry DOI: 10.7270/Q23B60T1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 1 (Mus musculus) | BDBM50094548 (1,3-Bis-(4-fluoro-phenyl)-2,4,5,6-tetrahydro-cyclo...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherche Servier Curated by ChEMBL | Assay Description Inhibition against prostaglandin G/H synthase 1 from mouse resident macrophages | J Med Chem 43: 4582-93 (2001) BindingDB Entry DOI: 10.7270/Q23B60T1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 1 (Mus musculus) | BDBM50094534 (1,3-Bis-(4-fluoro-phenyl)-4,5,6,7-tetrahydro-2H-is...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherche Servier Curated by ChEMBL | Assay Description Inhibition against prostaglandin G/H synthase 1 from mouse resident macrophages | J Med Chem 43: 4582-93 (2001) BindingDB Entry DOI: 10.7270/Q23B60T1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 1 (Mus musculus) | BDBM50094539 (3,5-Bis-(4-fluoro-phenyl)-4-aza-tricyclo[5.2.1.0*2...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherche Servier Curated by ChEMBL | Assay Description Inhibition against prostaglandin G/H synthase 1 from mouse resident macrophages | J Med Chem 43: 4582-93 (2001) BindingDB Entry DOI: 10.7270/Q23B60T1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 1 (Mus musculus) | BDBM50094540 (1,3-diphenyl-4,5,6,7-tetrahydro-2H-isoindole | CHE...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherche Servier Curated by ChEMBL | Assay Description Inhibition against prostaglandin G/H synthase 1 from mouse resident macrophages | J Med Chem 43: 4582-93 (2001) BindingDB Entry DOI: 10.7270/Q23B60T1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 1 (Mus musculus) | BDBM50094535 (1,3-diphenyl-4,7-dihydro-2H-isoindole | CHEMBL1408...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherche Servier Curated by ChEMBL | Assay Description Inhibition against prostaglandin G/H synthase 1 from mouse resident macrophages | J Med Chem 43: 4582-93 (2001) BindingDB Entry DOI: 10.7270/Q23B60T1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 1 (Mus musculus) | BDBM50293282 (CHEMBL504535 | Imrecoxib) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 114 | n/a | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Medical Sciences Curated by ChEMBL | Assay Description Inhibition of COX1 in mouse peritoneal macrophages | Bioorg Med Chem Lett 19: 2270-2 (2009) Article DOI: 10.1016/j.bmcl.2009.02.090 BindingDB Entry DOI: 10.7270/Q2CF9PZR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 1 (Mus musculus) | BDBM50293282 (CHEMBL504535 | Imrecoxib) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 115 | n/a | n/a | n/a | n/a | n/a | n/a |
PharmaPhase Co., Ltd Curated by ChEMBL | Assay Description Inhibition of calcimycin-induced COX-1 in peritoneal macrophage of C57BL/J6 mouse assessed as 6-Keto prostaglandin F1alpha formation preincubated for... | Bioorg Med Chem 22: 2005-32 (2014) Article DOI: 10.1016/j.bmc.2014.02.017 BindingDB Entry DOI: 10.7270/Q2WS8VS9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 1 (Mus musculus) | BDBM50474742 (CHEMBL166295) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 177 | n/a | n/a | n/a | n/a | n/a | n/a |
AmorePacific R&D Center Curated by ChEMBL | Assay Description In vitro inhibitory activity against prostaglandin G/H synthase 1 using mouse peritoneal macrophage method | J Med Chem 47: 792-804 (2004) Article DOI: 10.1021/jm020545z BindingDB Entry DOI: 10.7270/Q2QZ2DPG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 1 (Mus musculus) | BDBM50094551 (3,5-Bis-(4-fluoro-phenyl)-4-aza-tricyclo[5.2.2.0*2...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 230 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherche Servier Curated by ChEMBL | Assay Description Inhibition against prostaglandin G/H synthase 1 from mouse resident macrophages | J Med Chem 43: 4582-93 (2001) BindingDB Entry DOI: 10.7270/Q23B60T1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 1 (Mus musculus) | BDBM50094542 (1,3-Diphenyl-2,4,5,6-tetrahydro-cyclopenta[c]pyrro...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 250 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherche Servier Curated by ChEMBL | Assay Description Inhibition against prostaglandin G/H synthase 1 from mouse resident macrophages | J Med Chem 43: 4582-93 (2001) BindingDB Entry DOI: 10.7270/Q23B60T1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 1 (Mus musculus) | BDBM50094546 (3,5-Diphenyl-4-aza-tricyclo[5.2.2.0*2,6*]undeca-2,...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 250 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherche Servier Curated by ChEMBL | Assay Description Inhibition against prostaglandin G/H synthase 1 from mouse resident macrophages | J Med Chem 43: 4582-93 (2001) BindingDB Entry DOI: 10.7270/Q23B60T1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 1 (Mus musculus) | BDBM50094563 (1,3-Di-p-tolyl-4,5,6,7-tetrahydro-2H-isoindole | 1...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 500 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherche Servier Curated by ChEMBL | Assay Description Inhibition against prostaglandin G/H synthase 1 from mouse resident macrophages | J Med Chem 43: 4582-93 (2001) BindingDB Entry DOI: 10.7270/Q23B60T1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 1 (Mus musculus) | BDBM50094561 (3,5-Bis-(4-fluoro-phenyl)-4-aza-tricyclo[5.2.1.0*2...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 500 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherche Servier Curated by ChEMBL | Assay Description Inhibition against prostaglandin G/H synthase 1 from mouse resident macrophages | J Med Chem 43: 4582-93 (2001) BindingDB Entry DOI: 10.7270/Q23B60T1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 1 (Mus musculus) | BDBM50094547 (1,3-Bis-(4-methylsulfanyl-phenyl)-4,5,6,7-tetrahyd...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 500 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherche Servier Curated by ChEMBL | Assay Description Inhibition against prostaglandin G/H synthase 1 from mouse resident macrophages | J Med Chem 43: 4582-93 (2001) BindingDB Entry DOI: 10.7270/Q23B60T1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 1 (Mus musculus) | BDBM50094537 (1-(4-(1H-imidazol-1-yl)phenyl)-3-(4-fluorophenyl)-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 500 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherche Servier Curated by ChEMBL | Assay Description Inhibition against prostaglandin G/H synthase 1 from mouse resident macrophages | J Med Chem 43: 4582-93 (2001) BindingDB Entry DOI: 10.7270/Q23B60T1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 1 (Mus musculus) | BDBM50474765 (CHEMBL353959) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 674 | n/a | n/a | n/a | n/a | n/a | n/a |
AmorePacific R&D Center Curated by ChEMBL | Assay Description In vitro inhibitory activity against prostaglandin G/H synthase 1 using mouse peritoneal macrophage method | J Med Chem 47: 792-804 (2004) Article DOI: 10.1021/jm020545z BindingDB Entry DOI: 10.7270/Q2QZ2DPG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 1 (Mus musculus) | BDBM50474760 (CG-100649 | CG100649 | Polmacoxib) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem | Article PubMed | n/a | n/a | 830 | n/a | n/a | n/a | n/a | n/a | n/a |
AmorePacific R&D Center Curated by ChEMBL | Assay Description In vitro inhibitory activity against prostaglandin G/H synthase 1 using mouse peritoneal macrophage method | J Med Chem 47: 792-804 (2004) Article DOI: 10.1021/jm020545z BindingDB Entry DOI: 10.7270/Q2QZ2DPG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 1 (Mus musculus) | BDBM50094532 (1,3-Diphenyl-4,5,6,7-tetrahydro-isoindol-2-ylamine...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherche Servier Curated by ChEMBL | Assay Description Inhibition against prostaglandin G/H synthase 1 from mouse resident macrophages | J Med Chem 43: 4582-93 (2001) BindingDB Entry DOI: 10.7270/Q23B60T1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 1 (Mus musculus) | BDBM50094552 (1,3-Diphenyl-benzo[c]thiophene | CHEMBL143653) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents | PubMed | n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherche Servier Curated by ChEMBL | Assay Description Inhibition against prostaglandin G/H synthase 1 from mouse resident macrophages | J Med Chem 43: 4582-93 (2001) BindingDB Entry DOI: 10.7270/Q23B60T1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 1 (Mus musculus) | BDBM50094550 (3,5-Diphenyl-4-aza-tricyclo[5.2.2.0*2,6*]undeca-2,...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherche Servier Curated by ChEMBL | Assay Description Inhibition against prostaglandin G/H synthase 1 from mouse resident macrophages | J Med Chem 43: 4582-93 (2001) BindingDB Entry DOI: 10.7270/Q23B60T1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 1 (Mus musculus) | BDBM50094556 (CHEMBL140171 | N-(1,3-Diphenyl-4,5,6,7-tetrahydro-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | PubMed | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherche Servier Curated by ChEMBL | Assay Description Inhibition against prostaglandin G/H synthase 1 from mouse resident macrophages | J Med Chem 43: 4582-93 (2001) BindingDB Entry DOI: 10.7270/Q23B60T1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 1 (Mus musculus) | BDBM50094528 (5,6-Dimethyl-1,3-diphenyl-4,5,6,7-tetrahydro-2H-is...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherche Servier Curated by ChEMBL | Assay Description Inhibition against prostaglandin G/H synthase 1 from mouse resident macrophages | J Med Chem 43: 4582-93 (2001) BindingDB Entry DOI: 10.7270/Q23B60T1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 1 (Mus musculus) | BDBM50094549 (1,3-Bis-(4-methoxy-phenyl)-4,5,6,7-tetrahydro-2H-i...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherche Servier Curated by ChEMBL | Assay Description Inhibition against prostaglandin G/H synthase 1 from mouse resident macrophages | J Med Chem 43: 4582-93 (2001) BindingDB Entry DOI: 10.7270/Q23B60T1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 1 (Mus musculus) | BDBM50094553 (1,3-Bis-(4-imidazol-1-yl-phenyl)-4,5,6,7-tetrahydr...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherche Servier Curated by ChEMBL | Assay Description Inhibition against prostaglandin G/H synthase 1 from mouse resident macrophages | J Med Chem 43: 4582-93 (2001) BindingDB Entry DOI: 10.7270/Q23B60T1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 1 (Mus musculus) | BDBM50094538 (4,6-Diphenyl-1,2,3,5-tetrahydro-pyrrolo[3,4-c]pyrr...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherche Servier Curated by ChEMBL | Assay Description Inhibition against prostaglandin G/H synthase 1 from mouse resident macrophages | J Med Chem 43: 4582-93 (2001) BindingDB Entry DOI: 10.7270/Q23B60T1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 1 (Mus musculus) | BDBM50361584 (CHEMBL1939671) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£"Sapienza" Curated by ChEMBL | Assay Description Inhibition of COX-1-mediated PGE2 production in arachidonic acid-stimulated mouse J774 cells incubated for 15 mins prior to arachidonic acid-challeng... | J Med Chem 54: 7759-71 (2011) Article DOI: 10.1021/jm200715n BindingDB Entry DOI: 10.7270/Q2W37WR0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 1 (Mus musculus) | BDBM50310340 (3-(4-bromophenyl)-5-nitrobenzo[1.3.2]dithiazolium-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
National Taiwan University Curated by ChEMBL | Assay Description Inhibition of COX1 in mouse RAW264.7 cells by enzyme immunoassay | Bioorg Med Chem 18: 597-604 (2010) Article DOI: 10.1016/j.bmc.2009.12.008 BindingDB Entry DOI: 10.7270/Q2RF5V4Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 1 (Mus musculus) | BDBM50029593 (CHEMBL7162 | N-(2-(cyclohexyloxy)-4-nitrophenyl)me...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 1.67E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Yeungnam University Curated by ChEMBL | Assay Description Inhibitory activity against murine prostaglandin G/H synthase 1. | Bioorg Med Chem Lett 14: 2559-62 (2004) Article DOI: 10.1016/j.bmcl.2004.02.099 BindingDB Entry DOI: 10.7270/Q2VD7005 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 1 (Mus musculus) | BDBM50474770 (CHEMBL353965) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.99E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
AmorePacific R&D Center Curated by ChEMBL | Assay Description In vitro inhibitory activity against prostaglandin G/H synthase 1 using mouse peritoneal macrophage method | J Med Chem 47: 792-804 (2004) Article DOI: 10.1021/jm020545z BindingDB Entry DOI: 10.7270/Q2QZ2DPG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 1 (Mus musculus) | BDBM50310339 (3-(4-bromophenyl)-6-nitrobenzo[1.3.2]dithiazolium-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 2.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
National Taiwan University Curated by ChEMBL | Assay Description Inhibition of COX1 in mouse RAW264.7 cells by enzyme immunoassay | Bioorg Med Chem 18: 597-604 (2010) Article DOI: 10.1016/j.bmc.2009.12.008 BindingDB Entry DOI: 10.7270/Q2RF5V4Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 1 (Mus musculus) | BDBM50094559 (1,3-Diphenyl-2,3-dihydro-1H-isoindole | CHEMBL1400...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | >2.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherche Servier Curated by ChEMBL | Assay Description Inhibition against prostaglandin G/H synthase 1 from mouse resident macrophages | J Med Chem 43: 4582-93 (2001) BindingDB Entry DOI: 10.7270/Q23B60T1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 1 (Mus musculus) | BDBM50094536 (1,3-Diphenyl-2,3-dihydro-1H-isoindole | CHEMBL1412...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | >2.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherche Servier Curated by ChEMBL | Assay Description Inhibition against prostaglandin G/H synthase 1 from mouse resident macrophages | J Med Chem 43: 4582-93 (2001) BindingDB Entry DOI: 10.7270/Q23B60T1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 1 (Mus musculus) | BDBM50094557 (6,7-Diphenyl-2,3-dihydro-1H-pyrrolizine | CHEMBL34...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | PubMed | n/a | n/a | 2.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherche Servier Curated by ChEMBL | Assay Description Inhibition against prostaglandin G/H synthase 1 from mouse resident macrophages | J Med Chem 43: 4582-93 (2001) BindingDB Entry DOI: 10.7270/Q23B60T1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 1 (Mus musculus) | BDBM50293281 (4-(4-(4-(methylsulfonyl)phenyl)-2-oxo-1-propyl-2,5...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.78E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Medical Sciences Curated by ChEMBL | Assay Description Inhibition of COX1 in mouse peritoneal macrophages | Bioorg Med Chem Lett 19: 2270-2 (2009) Article DOI: 10.1016/j.bmcl.2009.02.090 BindingDB Entry DOI: 10.7270/Q2CF9PZR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 1 (Mus musculus) | BDBM50430956 (CHEMBL2337405) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena Curated by ChEMBL | Assay Description Inhibition of arachidonic acid-induced COX1 activity in mouse J774 cells assessed as decrease in PGE2 levels incubated for 15 mins prior to arachidon... | J Med Chem 56: 3191-206 (2013) Article DOI: 10.1021/jm301370e BindingDB Entry DOI: 10.7270/Q2JS9RSB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 1 (Mus musculus) | BDBM50361595 (CHEMBL1939514 | US9162979, 5-II) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.18E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£"Sapienza" Curated by ChEMBL | Assay Description Inhibition of COX-1-mediated PGE2 production in arachidonic acid-stimulated mouse J774 cells incubated for 15 mins prior to arachidonic acid-challeng... | J Med Chem 54: 7759-71 (2011) Article DOI: 10.1021/jm200715n BindingDB Entry DOI: 10.7270/Q2W37WR0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 1 (Mus musculus) | BDBM11639 (4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 3.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Università La Sapienza Curated by ChEMBL | Assay Description Inhibition of COX1 in arachidonic acid-stimulated mouse J774 cells assessed as inhibition of PGE2 production after 15 mins by radioimmunoassay | Bioorg Med Chem 16: 8072-81 (2008) Article DOI: 10.1016/j.bmc.2008.07.058 BindingDB Entry DOI: 10.7270/Q24J0DZW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 1 (Mus musculus) | BDBM50430950 (CHEMBL2337398 | US9162979, 42-II) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena Curated by ChEMBL | Assay Description Inhibition of arachidonic acid-induced COX1 activity in mouse J774 cells assessed as decrease in PGE2 levels incubated for 15 mins prior to arachidon... | J Med Chem 56: 3191-206 (2013) Article DOI: 10.1021/jm301370e BindingDB Entry DOI: 10.7270/Q2JS9RSB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 1 (Mus musculus) | BDBM11639 (4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 3.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Università La Sapienza Curated by ChEMBL | Assay Description Inhibition of COX1 in mouse J774 cells assessed as arachidonic acid-induced PGE2 levels by radio immunoassay | J Med Chem 50: 5403-11 (2007) Article DOI: 10.1021/jm0707525 BindingDB Entry DOI: 10.7270/Q2PK0FV8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 1 (Mus musculus) | BDBM11639 (4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 3.84E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Citation and Details Article DOI: 10.1016/j.ejmech.2022.114615 BindingDB Entry DOI: 10.7270/Q2ZK5MMK | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 1 (Mus musculus) | BDBM11639 (4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 3.84E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Sapienza Curated by ChEMBL | Assay Description Inhibition of COX1 in mouse J774 cells using arachidonic acid as substrate assessed as inhibition of PGE2 production incubated for 15 mins prior to s... | Bioorg Med Chem 21: 3695-701 (2013) Article DOI: 10.1016/j.bmc.2013.04.031 BindingDB Entry DOI: 10.7270/Q2GT5R3K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 1 (Mus musculus) | BDBM11639 (4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 3.84E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£"Sapienza" Curated by ChEMBL | Assay Description Inhibition of COX-1-mediated PGE2 production in arachidonic acid-stimulated mouse J774 cells incubated for 15 mins prior to arachidonic acid-challeng... | J Med Chem 54: 7759-71 (2011) Article DOI: 10.1021/jm200715n BindingDB Entry DOI: 10.7270/Q2W37WR0 | |||||||||||
More data for this Ligand-Target Pair |
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