Compile Data Set for Download or QSAR

Found 3 hits for UniProtKB: Q7LG56   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ribonucleoside-diphosphate reductase large subunit/subunit M2 B (Homo sapiens (Human))	BDBM50497567 (CHEMBL3337770) Show SMILES CCCC(CCC)C(=O)OC[C@H]1O[C@H]([C@H](O)[C@]1(C)O)n1cnc2c(N)ncnc12 |r| Show InChI InChI=1S/C19H29N5O5/c1-4-6-11(7-5-2)18(26)28-8-12-19(3,27)14(25)17(29-12)24-10-23-13-15(20)21-9-22-16(13)24/h9-12,14,17,25,27H,4-8H2,1-3H3,(H2,20,21,22)/t12-,14+,17-,19-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	4.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Camerino Curated by ChEMBL					Assay Description Competitive inhibition of human recombinant ribonucleotide reductase in presence of varying levels of ATP by Dixon plot				Bioorg Med Chem Lett 24: 5304-9 (2014) Article DOI: 10.1016/j.bmcl.2014.09.046 BindingDB Entry DOI: 10.7270/Q22Z18H9
					More data for this Ligand-Target Pair
Ribonucleoside-diphosphate reductase large subunit/subunit M2/subunit M2 B (Homo sapiens (Human))	BDBM50174197 ((S)-3-(2-((3S,3aR,5S,7S,7aS)-7-((3-(9H-fluoren-9-y...) Show SMILES CC(C)CO[C@@H]1C[C@H]2[C@H](O)CN(CC(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc3ccccc3)C(O)=O)[C@@H]2[C@@H](COC(=O)CCC2c3ccccc3-c3ccccc23)O1 Show InChI InChI=1S/C43H51N3O11/c1-25(2)23-56-40-19-32-35(47)21-46(22-37(48)44-33(20-38(49)50)42(52)45-34(43(53)54)18-26-10-4-3-5-11-26)41(32)36(57-40)24-55-39(51)17-16-31-29-14-8-6-12-27(29)28-13-7-9-15-30(28)31/h3-15,25,31-36,40-41,47H,16-24H2,1-2H3,(H,44,48)(H,45,52)(H,49,50)(H,53,54)/t32-,33-,34-,35+,36+,40-,41-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Inhibition of mammalian ribonucleotide reductase (mRR)				Bioorg Med Chem Lett 15: 5146-9 (2005) Article DOI: 10.1016/j.bmcl.2005.08.062 BindingDB Entry DOI: 10.7270/Q2RB745F
					More data for this Ligand-Target Pair
Ribonucleoside-diphosphate reductase large subunit/subunit M2 B (Homo sapiens (Human))	BDBM50214817 (CHEMBL236757 | N6-aminoadenosine) Show SMILES NNc1ncnc2n(cnc12)[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O Show InChI InChI=1S/C10H14N6O4/c11-15-8-5-9(13-2-12-8)16(3-14-5)10-7(19)6(18)4(1-17)20-10/h2-4,6-7,10,17-19H,1,11H2,(H,12,13,15)/t4-,6-,7-,10-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.44E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Camerino Curated by ChEMBL					Assay Description Inhibition of human recombinant ribonucleotide reductase p53R2/M1 expressed in Escherichia coli BL21 (DE3) after 30 mins by [3H]CDP reduction method				Eur J Med Chem 46: 1499-504 (2011) Article DOI: 10.1016/j.ejmech.2011.01.055 BindingDB Entry DOI: 10.7270/Q2K074KT
					More data for this Ligand-Target Pair