The following articles (labelled with PubMed ID or TBD) are for your review
PMID | Data | Article Title | Organization |
18053726 |
364 |
Inhibitors of proteases and amide hydrolases that employ an alpha-ketoheterocycle as a key enabling functionality. |
Johnson & Johnson Pharmaceutical Research & Development |
16686541 |
10 |
Discovery of a potent, nonpolyglutamatable inhibitor of glycinamide ribonucleotide transformylase. |
The Scripps Research Institute |
10479275 |
5 |
A multisubstrate adduct inhibitor of AICAR transformylase. |
The Pennsylvania State University |
3121855 |
21 |
Synthesis and biological evaluation of 8-deazahomofolic acid and its tetrahydro derivative. |
Sri International |
15911265 |
2 |
Discovery of AICAR Tfase inhibitors that disrupt requisite enzyme dimerization. |
The Scripps Research Institute |
15615517 |
17 |
Virtual screening of human 5-aminoimidazole-4-carboxamide ribonucleotide transformylase against the NCI diversity set by use of AutoDock to identify novel nonfolate inhibitors. |
The Scripps Research Institute |
32658475 |
19 |
The Structural Basis for Nonsteroidal Anti-Inflammatory Drug Inhibition of Human Dihydrofolate Reductase. |
University of Tennessee |
10888335 |
5 |
Design, synthesis, and biological evaluation of fluoronitrophenyl substituted folate analogues as potential inhibitors of GAR transformylase and AICAR transformylase. |
The Scripps Research Institute |
8164259 |
44 |
Classical and nonclassical furo[2,3-d]pyrimidines as novel antifolates: synthesis and biological activities. |
Duquesne University |
3184124 |
28 |
Synthesis and antifolate activity of 5-methyl-5,10-dideaza analogues of aminopterin and folic acid and an alternative synthesis of 5,10-dideazatetrahydrofolic acid, a potent inhibitor of glycinamide ribonucleotide formyltransferase. |
Southern Research Institute |
2542557 |
14 |
Folate analogues. 32. Synthesis and biological evaluation of 2-desamino-2-methyl-N10-propargyl-5,8-dideazafolic acid and related compounds. |
University of South Alabama |
28830032 |
9 |
Novel 6-substituted benzoyl and non-benzoyl straight chain pyrrolo[2,3-d]pyrimidines as potential antitumor agents with multitargeted inhibition of TS, GARFTase and AICARFTase. |
Hebei Medical University |
2299624 |
12 |
Synthesis and biological activity of an acyclic analogue of 5,6,7,8-tetrahydrofolic acid, N-[4-[[3-(2,4-diamino-1,6-dihydro-6-oxo-5- pyrimidinyl)propyl]amino]-benzoyl]-L-glutamic acid. |
Wellcome Research Laboratories |
1573633 |
15 |
Synthesis and biological activity of open-chain analogues of 5,6,7,8-tetrahydrofolic acid--potential antitumor agents. |
Wellcome Research Laboratories |
29072452 |
42 |
Discovery of N-(6-Fluoro-1-oxo-1,2-dihydroisoquinolin-7-yl)-5-[(3R)-3-hydroxypyrrolidin-1-yl]thiophene-2-sulfonamide (LSN 3213128), a Potent and Selective Nonclassical Antifolate Aminoimidazole-4-carboxamide Ribonucleotide Formyltransferase (AICARFT) Inhibitor Effective at Tumor Suppression in a Can |
Eli Lilly |
1433179 |
13 |
5,10-Methylenetetrahydro-5-deazafolic acid and analogues: synthesis and biological activities. |
Duquesne University |
19968566 |
40 |
3D-QSAR, molecular docking studies, and binding mode prediction of thiolactomycin analogs as mtFabH inhibitors. |
China Pharmaceutical University |
1315531 |
17 |
Molecular cloning and functional characterization of a human 5-HT1B serotonin receptor: a homologue of the rat 5-HT1B receptor with 5-HT1D-like pharmacological specificity. |
Veterans Affairs Medical Center |