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22 articles for thisTarget


The following articles (labelled with PubMed ID or TBD) are for your review
PMIDDataArticle TitleOrganization
18053726 364 Inhibitors of proteases and amide hydrolases that employ an alpha-ketoheterocycle as a key enabling functionality.EBI Johnson & Johnson Pharmaceutical Research & Development
16686541 10 Discovery of a potent, nonpolyglutamatable inhibitor of glycinamide ribonucleotide transformylase.EBI The Scripps Research Institute
10479275 5 A multisubstrate adduct inhibitor of AICAR transformylase.EBI The Pennsylvania State University
3121855 21 Synthesis and biological evaluation of 8-deazahomofolic acid and its tetrahydro derivative.EBI Sri International
15911265 2 Discovery of AICAR Tfase inhibitors that disrupt requisite enzyme dimerization.EBI The Scripps Research Institute
15615517 17 Virtual screening of human 5-aminoimidazole-4-carboxamide ribonucleotide transformylase against the NCI diversity set by use of AutoDock to identify novel nonfolate inhibitors.EBI The Scripps Research Institute
32658475 19 The Structural Basis for Nonsteroidal Anti-Inflammatory Drug Inhibition of Human Dihydrofolate Reductase.EBI University of Tennessee
10888335 5 Design, synthesis, and biological evaluation of fluoronitrophenyl substituted folate analogues as potential inhibitors of GAR transformylase and AICAR transformylase.EBI The Scripps Research Institute
8164259 44 Classical and nonclassical furo[2,3-d]pyrimidines as novel antifolates: synthesis and biological activities.EBI Duquesne University
3184124 28 Synthesis and antifolate activity of 5-methyl-5,10-dideaza analogues of aminopterin and folic acid and an alternative synthesis of 5,10-dideazatetrahydrofolic acid, a potent inhibitor of glycinamide ribonucleotide formyltransferase.EBI Southern Research Institute
2542557 14 Folate analogues. 32. Synthesis and biological evaluation of 2-desamino-2-methyl-N10-propargyl-5,8-dideazafolic acid and related compounds.EBI University of South Alabama
28830032 9 Novel 6-substituted benzoyl and non-benzoyl straight chain pyrrolo[2,3-d]pyrimidines as potential antitumor agents with multitargeted inhibition of TS, GARFTase and AICARFTase.EBI Hebei Medical University
2299624 12 Synthesis and biological activity of an acyclic analogue of 5,6,7,8-tetrahydrofolic acid, N-[4-[[3-(2,4-diamino-1,6-dihydro-6-oxo-5- pyrimidinyl)propyl]amino]-benzoyl]-L-glutamic acid.EBI Wellcome Research Laboratories
1573633 15 Synthesis and biological activity of open-chain analogues of 5,6,7,8-tetrahydrofolic acid--potential antitumor agents.EBI Wellcome Research Laboratories
29072452 42 Discovery of N-(6-Fluoro-1-oxo-1,2-dihydroisoquinolin-7-yl)-5-[(3R)-3-hydroxypyrrolidin-1-yl]thiophene-2-sulfonamide (LSN 3213128), a Potent and Selective Nonclassical Antifolate Aminoimidazole-4-carboxamide Ribonucleotide Formyltransferase (AICARFT) Inhibitor Effective at Tumor Suppression in a CanEBI Eli Lilly
1433179 13 5,10-Methylenetetrahydro-5-deazafolic acid and analogues: synthesis and biological activities.EBI Duquesne University
19968566 40 3D-QSAR, molecular docking studies, and binding mode prediction of thiolactomycin analogs as mtFabH inhibitors.BDB China Pharmaceutical University
1315531 17 Molecular cloning and functional characterization of a human 5-HT1B serotonin receptor: a homologue of the rat 5-HT1B receptor with 5-HT1D-like pharmacological specificity.BDB Veterans Affairs Medical Center