The following articles (labelled with PubMed ID or TBD) are for your review
| PMID | Data | Article Title | Organization |
|---|
| 7683054 |
115 |
Synthesis and evaluation of 2-pyridinone derivatives as HIV-1-specific reverse transcriptase inhibitors. 4. 3-[2-(Benzoxazol-2-yl)ethyl]-5-ethyl-6-methylpyridin-2(1H)-one and analogues. |
Merck Reserch Laboratories |
| 15537346 |
15 |
Design of Non-Nucleoside Inhibitors of HIV-1 Reverse Transcriptase with Improved Drug Resistance Properties. 1. |
University of Oxford |
| 11052800 |
7 |
Synthesis and antiviral activity of 4-benzyl pyridinone derivatives as potent and selective non-nucleoside human immunodeficiency virus type 1 reverse transcriptase inhibitors. |
Institut Curie |
| 15857150 |
9 |
Computational strategies in discovering novel non-nucleoside inhibitors of HIV-1 RT. |
Universita Di Messina |
| 15519161 |
54 |
Studies of nonnucleoside HIV-1 reverse transcriptase inhibitors. Part 1: Design and synthesis of thiazolidenebenzenesulfonamides. |
Yamanouchi Pharmaceutical |
| 15670903 |
92 |
Studies of non-nucleoside HIV-1 reverse transcriptase inhibitors. Part 2: synthesis and structure-activity relationships of 2-cyano and 2-hydroxy thiazolidenebenzenesulfonamide derivatives. |
Yamanouchi Pharmaceutical |
| 7504733 |
33 |
Synthesis and anti-HIV-1 activity of a series of imidazo[1,5-b]pyridazines. |
Glaxo Group Research |
| 7678654 |
30 |
Synthesis and evaluation of 2-pyridinone derivatives as specific HIV-1 reverse transcriptase inhibitors. 3. Pyridyl and phenyl analogs of 3-aminopyridin-2(1H)-one. |
Merck Research Laboratories |
| 7520079 |
13 |
Synthesis of a series of 4-(arylethynyl)-6-chloro-4-cyclopropyl-3,4-dihydroquinazolin-2(1H)-ones as novel non-nucleoside HIV-1 reverse transcriptase inhibitors. |
Merck Research Laboratories |
| 11459666 |
20 |
Synthesis and evaluation of novel quinolinones as HIV-1 reverse transcriptase inhibitors. |
Dupont Pharmaceuticals |
| 10937734 |
30 |
Synthesis and evaluation of quinoxalinones as HIV-1 reverse transcriptase inhibitors. |
Dupont Pharmaceuticals |
| 10576692 |
17 |
Synthesis and evaluation of benzoxazinones as HIV-1 reverse transcriptase inhibitors. Analogs of Efavirenz (SUSTIVA). |
Dupont Pharmaceuticals |
| 10522695 |
18 |
Synthesis and evaluation of analogs of Efavirenz (SUSTIVA) as HIV-1 reverse transcriptase inhibitors. |
Dupont Pharmaceuticals |
| 11378361 |
25 |
4,1-Benzoxazepinone analogues of efavirenz (Sustiva) as HIV-1 reverse transcriptase inhibitors. |
Dupont Pharmaceuticals |
| 10821714 |
29 |
Inhibition of clinically relevant mutant variants of HIV-1 by quinazolinone non-nucleoside reverse transcriptase inhibitors. |
Dupont Pharmaceuticals |
| 10698450 |
21 |
Bioisosteric modification of PETT-HIV-1 RT-inhibitors: synthesis and biological evaluation. |
Medivir |
| 10579849 |
27 |
Novel modifications in the alkenyldiarylmethane (ADAM) series of non-nucleoside reverse transcriptase inhibitors. |
Purdue University |
| 12057671 |
16 |
Synthesis of substituted diarylmethylenepiperidines (DAMPs), a novel class of anti-HIV agents. |
Purdue University |
| 11741777 |
15 |
Synthesis of alkenyldiarylmethane (ADAM) non-nucleoside HIV-1 reverse transcriptase inhibitors with non-identical aromatic rings. |
Purdue University |
| 11708913 |
41 |
The biological effects of structural variation at the meta position of the aromatic rings and at the end of the alkenyl chain in the alkenyldiarylmethane series of non-nucleoside reverse transcriptase inhibitors. |
Purdue University |
| 9622549 |
23 |
New alkenyldiarylmethanes with enhanced potencies as anti-HIV agents which act as non-nucleoside reverse transcriptase inhibitors. |
Purdue University |
| 10514285 |
66 |
Urea-PETT compounds as a new class of HIV-1 reverse transcriptase inhibitors. 3. Synthesis and further structure-activity relationship studies of PETT analogues. |
Medivir |
| 14761194 |
15 |
Computer-aided design, synthesis, and anti-HIV-1 activity in vitro of 2-alkylamino-6-[1-(2,6-difluorophenyl)alkyl]-3,4-dihydro-5-alkylpyrimidin-4(3H)-ones as novel potent non-nucleoside reverse transcriptase inhibitors, also active against the Y181C variant. |
Sapienza University of Rome |
| 12773052 |
14 |
Novel indolyl aryl sulfones active against HIV-1 carrying NNRTI resistance mutations: synthesis and SAR studies. |
Sapienza University of Rome |
| 8818233 |
18 |
5H-pyrrolo[1,2-b] [1,2,5]benzothiadiazepines (PBTDs): a novel class of non-nucleoside reverse transcriptase inhibitors. |
Sapienza University of Rome |
| 7650679 |
33 |
Synthesis and anti-HIV-1 activity of thio analogues of dihydroalkoxybenzyloxopyrimidines. |
Sapienza University of Rome |
| 9154967 |
10 |
Dihydro(alkylthio)(naphthylmethyl)oxopyrimidines: novel non-nucleoside reverse transcriptase inhibitors of the S-DABO series. |
Sapienza University of Rome |
| 10698447 |
6 |
1-[2-(Diphenylmethoxy)ethyl]-2-methyl-5-nitroimidazole: a potent lead for the design of novel NNRTIs. |
Sapienza University of Rome |
| 11931611 |
7 |
Synthesis, biological evaluation, and binding mode of novel 1-[2-(diarylmethoxy)ethyl]-2-methyl-5-nitroimidazoles targeted at the HIV-1 reverse transcriptase. |
Sapienza University of Rome |
| 10794705 |
13 |
Structure-based design, synthesis, and biological evaluation of novel pyrrolyl aryl sulfones: HIV-1 non-nucleoside reverse transcriptase inhibitors active at nanomolar concentrations. |
Sapienza University of Rome |
| 10052969 |
50 |
5-Alkyl-2-(alkylthio)-6-(2,6-dihalophenylmethyl)-3, 4-dihydropyrimidin-4(3H)-ones: novel potent and selective dihydro-alkoxy-benzyl-oxopyrimidine derivatives. |
Sapienza University of Rome |
| 8558522 |
26 |
2-Sulfonyl-4-chloroanilino moiety: a potent pharmacophore for the anti-human immunodeficiency virus type 1 activity of pyrrolyl aryl sulfones. |
Universita Di Roma |
| 11472208 |
24 |
Structure-based design, synthesis, and biological evaluation of conformationally restricted novel 2-alkylthio-6-[1-(2,6-difluorophenyl)alkyl]-3,4-dihydro-5-alkylpyrimidin-4(3H)-ones as non-nucleoside inhibitors of HIV-1 reverse transcriptase. |
Sapienza University of Rome |
| 10715167 |
8 |
Novel 1,5-diphenylpyrazole nonnucleoside HIV-1 reverse transcriptase inhibitors with enhanced activity versus the delavirdine-resistant P236L mutant: lead identification and SAR of 3- and 4-substituted derivatives. |
Upjohn |
| 7684450 |
26 |
Bis(heteroaryl)piperazine (BHAP) reverse transcriptase inhibitors: structure-activity relationships of novel substituted indole analogues and the identification of 1-[(5-methanesulfonamido-1H-indol-2-yl)-carbonyl]-4-[3- [(1-methylethyl)amino]-pyridinyl]piperazine monomethanesulfonate (U-90152S), a |
Upjohn |
| 7683725 |
30 |
5-chloro-3-(phenylsulfonyl)indole-2-carboxamide: a novel, non-nucleoside inhibitor of HIV-1 reverse transcriptase. |
Merck Research Laboratories |
| 1716683 |
16 |
2-Pyridinone derivatives: a new class of nonnucleoside, HIV-1-specific reverse transcriptase inhibitors. |
Merck Sharp and Dohme Research Laboratories |
| 8863804 |
141 |
Phenethylthiazolylthiourea (PETT) compounds as a new class of HIV-1 reverse transcriptase inhibitors. 2. Synthesis and further structure-activity relationship studies of PETT analogs. |
Eli Lilly |
| 8809165 |
120 |
Targeting delavirdine/atevirdine resistant HIV-1: identification of (alkylamino)piperidine-containing bis(heteroaryl)piperazines as broad spectrum HIV-1 reverse transcriptase inhibitors. |
Upjohn |
| 8523406 |
59 |
Phenethylthiazolethiourea (PETT) compounds, a new class of HIV-1 reverse transcriptase inhibitors. 1. Synthesis and basic structure-activity relationship studies of PETT analogs. |
Eli Lilly |
| 11384233 |
70 |
2-Amino-6-arylsulfonylbenzonitriles as non-nucleoside reverse transcriptase inhibitors of HIV-1. |
Glaxosmithkline |
| 7689109 |
83 |
Selective non-nucleoside HIV-1 reverse transcriptase inhibitors. New 2,3-dihydrothiazolo[2,3-a]isoindol-5(9bH)-ones and related compounds with anti-HIV-1 activity. |
Boehringer Mannheim |
| 1279173 |
72 |
Synthesis and evaluation of 2-pyridinone derivatives as HIV-1-specific reverse transcriptase inhibitors. 2. Analogues of 3-aminopyridin-2(1H)-one. |
Merck Research Laboratories |
| 1279172 |
22 |
Synthesis and evaluation of 2-pyridinone derivatives as HIV-1 specific reverse transcriptase inhibitors. 1. Phthalimidoalkyl and -alkylamino analogues. |
Merck Research Laboratories |
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