47 articles for thisTarget

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The following articles (labelled with PubMed ID or TBD) are for your review

PMID	Data	Article Title	Organization
28105265	6	Targeting the Inhibition of Tryptophan 2,3-Dioxygenase (TDO-2) for Cancer Treatment.	Therachem Research Medilab (India)
27994758	130	Fused Heterocyclic Compounds as Potent Indoleamine-2,3-dioxygenase 1 Inhibitors.	Indian Institute of Technology
26348881	54	Identification of Substituted Naphthotriazolediones as Novel Tryptophan 2,3-Dioxygenase (TDO) Inhibitors through Structure-Based Virtual Screening.	National Health Research Institutes
26207924	32	Challenges and Opportunities in the Discovery of New Therapeutics Targeting the Kynurenine Pathway.	Colorado College
22616902	165	Rational design of 4-aryl-1,2,3-triazoles for indoleamine 2,3-dioxygenase 1 inhibition.	Ludwig Center For Cancer Research of The University of Lausanne
22626654	7	Synthesis, crystal structures and electronic properties of isomers of chloro-pyridinylvinyl-1H-indoles.	University of Namur (Fundp)
21726069	98	Tryptophan 2,3-dioxygenase (TDO) inhibitors. 3-(2-(pyridyl)ethenyl)indoles as potential anticancer immunomodulators.	University of Namur
19507862	42	Discovery of potent competitive inhibitors of indoleamine 2,3-dioxygenase with in vivo pharmacodynamic activity and efficacy in a mouse melanoma model.	Incyte
32832022	33	Discovery of Potent and Orally Available Bicyclo[1.1.1]pentane-Derived Indoleamine-2,3-dioxygenase 1 (IDO1) Inhibitors.	Merck
32247733	43	Synthesis of novel tryptanthrin derivatives as dual inhibitors of indoleamine 2,3-dioxygenase 1 and tryptophan 2,3-dioxygenase.	Tongji University
31749906	52	Discovery of Amino-cyclobutarene-derived Indoleamine-2,3-dioxygenase 1 (IDO1) Inhibitors for Cancer Immunotherapy.	Merck
31445231	56	Discovery of phosphonamidate IDO1 inhibitors for the treatment of non-small cell lung cancer.	Nanjing Medical University
30321802	48	Tryptophan 2,3-dioxygenase inhibitory activities of tryptanthrin derivatives.	Fudan University
31999451	63	Bifunctional Naphthoquinone Aromatic Amide-Oxime Derivatives Exert Combined Immunotherapeutic and Antitumor Effects through Simultaneous Targeting of Indoleamine-2,3-dioxygenase and Signal Transducer and Activator of Transcription 3.	Guangxi Normal University
30773421	10	4,6-Substituted-1H-Indazoles as potent IDO1/TDO dual inhibitors.	Xihua University
31223453	103	Discovery of Imidazoisoindole Derivatives as Highly Potent and Orally Active Indoleamine-2,3-dioxygenase Inhibitors.	Shanghai Hengrui Pharmaceutical
31580660	120	-Benzyl/Aryl Substituted Tryptanthrin as Dual Inhibitors of Indoleamine 2,3-Dioxygenase and Tryptophan 2,3-Dioxygenase.	Fudan University
32292562	73	Implementation of the CYP Index for the Design of Selective Tryptophan-2,3-dioxygenase Inhibitors.	Genentech
32071686	64	Discovery of Hydroxyamidine Based Inhibitors of IDO1 for Cancer Immunotherapy with Reduced Potential for Glucuronidation.	Phenex Pharmaceuticals
30469041	114	Diaryl hydroxylamines as pan or dual inhibitors of indoleamine 2,3-dioxygenase-1, indoleamine 2,3-dioxygenase-2 and tryptophan dioxygenase.	Bryn Mawr College
30103191	45	Design, synthesis and biological evaluation of novel naphthoquinone derivatives as IDO1 inhibitors.	Peking University
30170925	40	Design, synthesis and structure-activity relationship study of novel naphthoindolizine and indolizinoquinoline-5,12-dione derivatives as IDO1 inhibitors.	Peking University
29795752	82	Aminoisoxazoles as Potent Inhibitors of Tryptophan 2,3-Dioxygenase 2 (TDO2).	Genentech
29456801	52	Identification of Potent Indoleamine 2,3-Dioxygenase 1 (IDO1) Inhibitors Based on a Phenylimidazole Scaffold.	University Health Network
29220788	33	Recent discovery of indoleamine-2,3-dioxygenase 1 inhibitors targeting cancer immunotherapy.	China Pharmaceutical University
29111717	64	Discovery of a Novel and Selective Indoleamine 2,3-Dioxygenase (IDO-1) Inhibitor 3-(5-Fluoro-1H-indol-3-yl)pyrrolidine-2,5-dione (EOS200271/PF-06840003) and Its Characterization as a Potential Clinical Candidate.	Iteos Therapeutics
17174378	12	Novel amidino-substituted benzimidazoles: synthesis of compounds and inhibition of dipeptidyl peptidase III.	The Josip Juraj Strossmayer University
18234496	12	Alpha,Beta-cyclic-beta-benzamido hydroxamic acids: Novel oxaspiro[4.4]nonane templates for the discovery of potent, selective, orally bioavailable inhibitors of tumor necrosis factor-alpha converting enzyme (TACE).	Bristol-Myers Squibb
17804234	42	5'-Phenyl-3'H-spiro[indoline-3,2'-[1,3,4]thiadiazol]-2-one inhibitors of ADAMTS-5 (aggrecanase-2).	Wyeth Research