The following articles (labelled with PubMed ID or TBD) are for your review
PMID | Data | Article Title | Organization |
28151653 |
35 |
Full Sequence Amino Acid Scanning of¿-Defensin RTD-1 Yields a Potent Anthrax Lethal Factor Protease Inhibitor. |
State University of New York |
26492514 |
56 |
Probing the S2' Subsite of the Anthrax Toxin Lethal Factor Using Novel N-Alkylated Hydroxamates. |
University of Minnesota |
25116076 |
14 |
Exploring the influence of the protein environment on metal-binding pharmacophores. |
University of California |
24290062 |
142 |
Small molecule inhibitors of anthrax lethal factor toxin. |
Microbiotix |
22960696 |
5 |
D-proline-based peptidomimetic inhibitors of anthrax lethal factor. |
TBA |
22342144 |
72 |
Antidotes to anthrax lethal factor intoxication. Part 3: Evaluation of core structures and further modifications to the C2-side chain. |
Panthera Biopharma |
20155918 |
72 |
Synthesis and biological evaluation of botulinum neurotoxin a protease inhibitors. |
Microbiotix |
17485504 |
4 |
Amiodarone and bepridil inhibit anthrax toxin entry into host cells. |
University of California |
18314330 |
4 |
Inhibitors of anthrax lethal factor based upon N-oleoyldopamine. |
Purdue University |
22082667 |
67 |
Time-dependent botulinum neurotoxin serotype A metalloprotease inhibitors. |
Microbiotix |
21334206 |
39 |
Antidotes to anthrax lethal factor intoxication. Part 2: structural modifications leading to improved in vivo efficacy. |
Panthera Biopharma |
21189019 |
22 |
Identifying chelators for metalloprotein inhibitors using a fragment-based approach. |
University of California |
20864339 |
29 |
Antidotes to anthrax lethal factor intoxication. Part 1: Discovery of potent lethal factor inhibitors with in vivo efficacy. |
Panthera Biopharma |
18378717 |
4 |
In vivo efficacy of beta-cyclodextrin derivatives against anthrax lethal toxin. |
National Institute of Allergy and Infectious Diseases |
20045647 |
35 |
Synthesis and optimization of thiadiazole derivatives as a novel class of substrate competitive c-Jun N-terminal kinase inhibitors. |
Institute For Medical Research |
19359184 |
131 |
Structure-activity relationship studies of a novel series of anthrax lethal factor inhibitors. |
Institute For Medical Research |
17574849 |
7 |
Inhibitors of anthrax lethal factor. |
Purdue University |
28927803 |
9 |
In-cell production of a genetically-encoded library based on the ?-defensin RTD-1 using a bacterial expression system. |
University of Southern California |
29198864 |
29 |
Small molecule inhibitors of anthrax edema factor. |
Hawaii Biotech |
27474803 |
20 |
In silico binding analysis and SAR elucidations of newly designed benzopyrazine analogs as potent inhibitors of thymidine phosphorylase. |
Universiti Teknologi Mara (Uitm) |
8524985 |
69 |
D4 dopamine receptor binding affinity does not distinguish between typical and atypical antipsychotic drugs. |
Case Western Reserve University |
17215127 |
12 |
Crystal structure of the PXR-T1317 complex provides a scaffold to examine the potential for receptor antagonism. |
University of North Carolina At Chapel Hill |
18318469 |
75 |
Discovery of a New Class of Potent, Selective, and Orally Bioavailable CRTH2 (DP2) Receptor Antagonists for the Treatment of Allergic Inflammatory Diseases. |
Merck Serono |
18318467 |
9 |
Arginine binding motifs: design and synthesis of galactose-derived arginine tweezers as galectin-3 inhibitors. |
Lund University |
18314943 |
27 |
Optimization of a Dihydropyrrolopyrazole Series of Transforming Growth Factor-beta Type I Receptor Kinase Domain Inhibitors: Discovery of an Orally Bioavailable Transforming Growth Factor-beta Receptor Type I Inhibitor as Antitumor Agent. |
Eli Lilly |