The following articles (labelled with PubMed ID or TBD) are for your review
| PMID | Data | Article Title | Organization |
|---|
| 28124907 |
3 |
Discovery and Synthesis of a Phosphoramidate Prodrug of a Pyrrolo[2,1-f][triazin-4-amino] Adenine C-Nucleoside (GS-5734) for the Treatment of Ebola and Emerging Viruses. |
Gilead Sciences |
| 24944743 |
3 |
Discovery and Synthesis of C-Nucleosides as Potential New Anti-HCV Agents. |
Biota Scientific Management |
| 24631359 |
10 |
N-Acyl-phosphoramidates as potential novel form of gemcitabine prodrugs. |
Polish Academy of Sciences |
| 8864237 |
4 |
Specific inhibition of human immunodeficiency virus type 1 reverse transcriptase mediated by soulattrolide, a coumarin isolated from the latex of calophyllum teysmannii. |
Chulalongkorn University |
| 16134946 |
55 |
4-Oxo-4,7-dihydrothieno[2,3-b]pyridines as non-nucleoside inhibitors of human cytomegalovirus and related herpesvirus polymerases. |
Pharmacia |
| 9622545 |
41 |
Newly synthesized L-enantiomers of 3'-fluoro-modified beta-2'-deoxyribonucleoside 5'-triphosphates inhibit hepatitis B DNA polymerases but not the five cellular DNA polymerases alpha, beta, gamma, delta, and epsilon nor HIV-1 reverse transcriptase. |
Max-Delbr�Ck-Centrum F�R Molekulare Medizin |
| 8246219 |
16 |
Isosteres of the DNA polymerase inhibitor aphidicolin as potential antiviral agents against human herpes viruses. |
Wellcome Research Laboratories |
| 6694166 |
5 |
Synthesis and characterization of N2-(p-n-butylphenyl)-2'-deoxyguanosine and its 5'-triphosphate and their inhibition of HeLa DNA polymerase alpha. |
TBA |
| 18852280 |
8 |
1,5-benzodiazepines, a novel class of hepatitis C virus polymerase nonnucleoside inhibitors. |
Tibotec |
| 19398642 |
10 |
GS-9191 is a novel topical prodrug of the nucleotide analog 9-(2-phosphonylmethoxyethyl)guanine with antiproliferative activity and possible utility in the treatment of human papillomavirus lesions. |
Gilead Sciences |
| 20516278 |
10 |
PSI-7851, a pronucleotide of beta-D-2'-deoxy-2'-fluoro-2'-C-methyluridine monophosphate, is a potent and pan-genotype inhibitor of hepatitis C virus replication. |
Pharmasset |
| 20403696 |
5 |
Modifications of C-2 on the pyrroloquinoline template aimed at the development of potent herpesvirus antivirals with improved aqueous solubility. |
Pfizer |
| 20167488 |
2 |
The design and development of 2-aryl-2-hydroxy ethylamine substituted 1H,7H-pyrido[1,2,3-de]quinoxaline-6-carboxamides as inhibitors of human cytomegalovirus polymerase. |
Pfizer |
| 20014868 |
6 |
N-sulfonylanthranilic acid derivatives as allosteric inhibitors of dengue viral RNA-dependent RNA polymerase. |
Novartis Institute For Tropical Diseases |
| 1705574 |
2 |
Differential Inhibition of Reverse Transcriptase and Various DNA Polymerases by Digallic Acid and Its Derivatives |
TBA |
| 16854079 |
57 |
Benzimidazole derivatives bearing substituted biphenyls as hepatitis C virus NS5B RNA-dependent RNA polymerase inhibitors: structure-activity relationship studies and identification of a potent and highly selective inhibitor JTK-109. |
Central Pharmaceutical Research Institute |
| 16722622 |
24 |
Discovery of proline sulfonamides as potent and selective hepatitis C virus NS5b polymerase inhibitors. Evidence for a new NS5b polymerase binding site. |
Wyeth Research |
| 16563761 |
48 |
Synthetic analogues of the manzamenones and plakoridines which inhibit DNA polymerase. |
The University of Manchester |
| 16455252 |
72 |
Benzimidazole inhibitors of hepatitis C virus NS5B polymerase: identification of 2-[(4-diarylmethoxy)phenyl]-benzimidazole. |
Central Pharmaceutical Research Institute |
| 16451063 |
139 |
3-(1,1-dioxo-2H-(1,2,4)-benzothiadiazin-3-yl)-4-hydroxy-2(1H)-quinolinones, potent inhibitors of hepatitis C virus RNA-dependent RNA polymerase. |
Glaxosmithkline |
| 15369402 |
32 |
Molecular design of cholesterols as inhibitors of DNA polymerase alpha. |
Frontier Research Center For Genome & Drug Discovery |
| 15261274 |
28 |
Identification of [(naphthalene-1-carbonyl)-amino]-acetic acid derivatives as nonnucleoside inhibitors of HCV NS5B RNA dependent RNA polymerase. |
Wyeth Research |
| 12238929 |
2 |
Enhancement of nucleoside cytotoxicity through nucleotide prodrugs. |
Southern Research Institute |
| 32324396 |
17 |
p62/SQSTM1, a Central but Unexploited Target: Advances in Its Physiological/Pathogenic Functions and Small Molecular Modulators. |
China Pharmaceutical University |
| 10999475 |
43 |
Naphthalene carboxamides as inhibitors of human cytomegalovirus DNA polymerase. |
Pharmacia |
| 30653317 |
104 |
Discovery of a Series of 2'-?-Fluoro,2'-?-bromo-ribonucleosides and Their Phosphoramidate Prodrugs as Potent Pan-Genotypic Inhibitors of Hepatitis C Virus. |
Emory University School of Medicine |
| 7752206 |
20 |
Inhibition of herpes simplex virus type 1 helicase-primase by (dichloroanilino)purines and -pyrimidines. |
Stanford University Medical School |
| 3806587 |
9 |
Synthesis, cell growth inhibition, and antitumor screening of 2-(p-n-butylanilino)purines and their nucleoside analogues. |
TBA |
| 28633899 |
8 |
Discovery of BMS-961955, an allosteric inhibitor of the hepatitis C virus NS5B polymerase. |
Bristol-Myers Squibb Research and Development |
| 28835346 |
3 |
The discovery of IDX21437: Design, synthesis and antiviral evaluation of 2'-?-chloro-2'-?-C-methyl branched uridine pronucleotides as potent liver-targeted HCV polymerase inhibitors. |
Idenix An Msd |
| 28595015 |
14 |
2'-Chloro,2'-fluoro Ribonucleotide Prodrugs with Potent Pan-genotypic Activity against Hepatitis C Virus Replication in Culture. |
Emory University |
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