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22 articles for thisTarget


The following articles (labelled with PubMed ID or TBD) are for your review
PMIDDataArticle TitleOrganization
25086681 57 Structure-based optimization of non-peptidic Cathepsin D inhibitors.EBI Merck
8120867 70 Non-peptide renin inhibitors containing 2-(((3-phenylpropyl)phosphoryl)oxy)alkanoic acid moieties as P2-P3 replacements.EBI E. Merck Darmstadt
8474103 123 Potent and selective inhibitors of an aspartyl protease-like endothelin converting enzyme identified in rat lung.EBI Abbott Laboratories
1635057 48 Structure-activity relationships of a series of 2-amino-4-thiazole-containing renin inhibitors.EBI Parke-Davis Pharmaceutical Research Division Of Warner-Lambert
1732531 88 Design and synthesis of potent, selective, and orally active fluorine-containing renin inhibitors.EBI Warner-Lambert
2066966 32 Renin inhibitors containing esters at the P2-position. Oral activity in a derivative of methyl aminomalonate.EBI Warner-Lambert
1956045 88 Substrate analogue renin inhibitors containing replacements of histidine in P2 or isosteres of the amide bond between P3 and P2 sites.EBI E. Merck Darmstadt
2120440 23 Orally potent human renin inhibitors derived from angiotensinogen transition state: design, synthesis, and mode of interaction.EBI Kissei Pharmaceutical
3783611 55 Inhibition of cathepsin D by substrate analogues containing statine and by analogues of pepstatin.EBI TBA
3531518 17 Design and synthesis of a potent and specific renin inhibitor with a prolonged duration of action in vivo.EBI TBA
3531517 17 Design and synthesis of potent and specific renin inhibitors containing difluorostatine, difluorostatone, and related analogues.EBI TBA
3906126 10 Difluorostatine- and difluorostatone-containing peptides as potent and specific renin inhibitors.EBI TBA
19615901 52 The P1N-isopropyl motif bearing hydroxyethylene dipeptide isostere analogues of aliskiren are in vitro potent inhibitors of the human aspartyl protease renin.EBI Nagasaki International University
 23 Novel low molecular renin inhibitors which show good oral blood pressure lowering effects in marmosetsEBI TBA
3309313 48 Renin inhibitors. Dipeptide analogues of angiotensinogen incorporating transition-state, nonpeptidic replacements at the scissile bond.EBI Abbott Laboratories
3276890 28 Renin inhibitors. Design and synthesis of a new class of conformationally restricted analogues of angiotensinogen.EBI Abbott Laboratories
3137345 19 Synthesis and biological activity of some transition-state inhibitors of human renin.EBI Ciba-Geigy
3126296 43 Inhibition of porcine pepsin by two substrate analogues containing statine. The effect of histidine at the P2 subsite on the inhibition of aspartic proteinases.EBI University Of Wisconsin
1901910 87 New inhibitors of human renin that contain novel replacements at the P2 site.EBI Warner-Lambert
1552498 55 Renin inhibitors containing alpha-heteroatom amino acids as P2 residues.EBI Warner-Lambert
1404233 68 Renin inhibitors containing new P1-P1' dipeptide mimetics with heterocycles in P1'.EBI E. Merck Darmstadt