31 articles for thisTarget

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The following articles (labelled with PubMed ID or TBD) are for your review

PMID	Data	Article Title	Organization
15177469	24	Pseudodeflectusin, a novel isochroman derivative from Aspergillus pseudodeflectus a parasite of the sea weed, Sargassum fusiform, as a selective human cancer cytotoxin.	Tokyo University of Science
27013392	10	Part 1: Notch-sparing¿-secretase inhibitors: The identification of novel naphthyl and benzofuranyl amide analogs.	Harvard Medical School
26898338	4	Synthesis of pyrimido[4,5-c]azepine- and pyrimido[4,5-c]oxepine-based¿-secretase modulators.	Bristol-Myers Squibb
26848108	36	Design and optimization of tricyclic gamma-secretase modulators.	Bristol-Myers Squibb Research and Development
26496070	96	Discovery of a Novel, Potent Spirocyclic Series of¿-Secretase Inhibitors.	Merck Research Laboratories
26288679	12	Fused Morphlinopyrimidines and Methods of Use Thereof.	Temple University
26142947	77	Potent benzoazepinone¿-secretase modulators with improved bioavailability.	Merck Research Laboratories
25582600	22	Discovery of indole-derived pyridopyrazine-1,6-dione¿-secretase modulators that target presenilin.	Pfizer
26005540	14	Design of Pyridopyrazine-1,6-dione¿-Secretase Modulators that Align Potency, MDR Efflux Ratio, and Metabolic Stability.	Pfizer
25575659	124	SAR-studies of¿-secretase modulators with PPAR¿-agonistic and 5-lipoxygenase-inhibitory activity for Alzheimer's disease.	Goethe-University Frankfurt
25454273	52	Anilinotriazoles as potent gamma secretase modulators.	Janssen Pharmaceutica
24900404	27	Discovery of SCH 900229, a Potent Presenilin 1 Selective ¿-Secretase Inhibitor for the Treatment of Alzheimer's Disease.	TBA
15588083	66	Stereochemical analysis of (hydroxyethyl)urea peptidomimetic inhibitors of gamma-secretase.	Harvard Medical School
15050631	21	Probing pockets S2-S4' of the gamma-secretase active site with (hydroxyethyl)urea peptidomimetics.	Harvard Medical School
16766183	24	Synthesis of biotinylated photoaffinity probes based on arylsulfonamide gamma-secretase inhibitors.	University of Tokyo
16682202	14	3-Substituted gem-cyclohexane sulfone based gamma-secretase inhibitors for Alzheimer's disease: conformational analysis and biological activity.	Merck Sharp and Dohme Research Laboratories
16682195	37	Novel gamma-secretase inhibitors discovered by library screening of in-house synthetic natural product intermediates.	University of Tokyo
16617016	13	3,4-Fused cyclohexyl sulfones as gamma-secretase inhibitors.	Neuroscience Research Centre
16054361	17	Cyclic sulfamide gamma-secretase inhibitors.	Merck Sharp and Dohme Research Laboratories
15863342	21	Aryl sulfones: a new class of gamma-secretase inhibitors.	Merck Sharp & Dohme Research Laboratories
15603957	62	A novel series of potent gamma-secretase inhibitors based on a benzobicyclo[4.2.1]nonane core.	Merck Sharp & Dohme Research Laboratories
15267231	17	Discovery of a Subnanomolar helical D-tridecapeptide inhibitor of gamma-secretase.	Harvard Medical School
14592525	18	High affinity, bioavailable 3-amino-1,4-benzodiazepine-based gamma-secretase inhibitors.	Merck Sharp & Dohme Research Laboratories
12643944	26	Inhibitors of Abeta production: solid-phase synthesis and SAR of alpha-hydroxycarbonyl derivatives.	Bristol-Myers Squibb Pharmaceutical Research Institute
31767402	21	Discovery of N-ethylpyridine-2-carboxamide derivatives as a novel scaffold for orally active ?-secretase modulators.	Astellas Pharma
31531188	14	Triazolo-azepine Inhibitors of ?-Secretase and Their Methods of Use.	Temple University
29249626	12	Discovery of novel scaffolds for ?-secretase modulators without an arylimidazole moiety.	Astellas Pharma
29057041	17	Discovery of a Tetrahydrobenzisoxazole Series of ?-Secretase Modulators.	Merck Research Laboratories
29735425	45	Discovery of tetrahydroindazoles as a novel class of potent and in vivo efficacious gamma secretase modulators.	Boehringer Ingelheim Pharma