The following articles (labelled with PubMed ID or TBD) are for your review
PMID | Data | Article Title | Organization |
28318946 |
3 |
Easy and rapid preparation of benzoylhydrazides and their diazene derivatives as inhibitors of 15-lipoxygenase. |
Universidad De Chile |
27802026 |
1 |
Magnetic Microbead Affinity Selection Screening (MagMASS) of Botanical Extracts for Inhibitors of 15-Lipoxygenase. |
University of Illinois At Chicago |
27477687 |
21 |
Design of a novel thiophene inhibitor of 15-lipoxygenase-1 with both anti-inflammatory and neuroprotective properties. |
University of Groningen |
26290290 |
4 |
Discovery of Novel 15-Lipoxygenase Activators To Shift the Human Arachidonic Acid Metabolic Network toward Inflammation Resolution. |
University of California San Diego |
26899595 |
32 |
A potent and selective inhibitor targeting human and murine 12/15-LOX. |
University of California |
26331552 |
37 |
Rational Development of a Potent 15-Lipoxygenase-1 Inhibitor with in Vitro and ex Vivo Anti-inflammatory Properties. |
University of Groningen |
26037322 |
100 |
3-Substituted pyrazoles and 4-substituted triazoles as inhibitors of human 15-lipoxygenase-1. |
Uppsala University |
26037319 |
14 |
N-Substituted pyrazole-3-carboxamides as inhibitors of human 15-lipoxygenase. |
Uppsala University |
24924423 |
21 |
Inhibitory and mechanistic investigations of oxo-lipids with human lipoxygenase isozymes. |
University of California |
25462262 |
98 |
Development and evaluation of ST-1829 based on 5-benzylidene-2-phenylthiazolones as promising agent for anti-leukotriene therapy. |
Goethe-University Frankfurt |
24920381 |
77 |
SAR studies on curcumin's pro-inflammatory targets: discovery of prenylated pyrazolocurcuminoids as potent and selective novel inhibitors of 5-lipoxygenase. |
University Jena |
24871899 |
31 |
Further studies on ethyl 5-hydroxy-indole-3-carboxylate scaffold: design, synthesis and evaluation of 2-phenylthiomethyl-indole derivatives as efficient inhibitors of human 5-lipoxygenase. |
University of Naples |
24684213 |
56 |
Potent and selective inhibitors of human reticulocyte 12/15-lipoxygenase as anti-stroke therapies. |
Harvard Medical School |
24393039 |
97 |
Synthesis and structure-activity relationship studies of 4-((2-hydroxy-3-methoxybenzyl)amino)benzenesulfonamide derivatives as potent and selective inhibitors of 12-lipoxygenase. |
National Institutes of Health |
23871907 |
64 |
Discovery and biological evaluation of novel 1,4-benzoquinone and related resorcinol derivatives that inhibit 5-lipoxygenase. |
University of Salerno |
23047230 |
13 |
Synthesis and SAR studies of mono O-prenylated coumarins as potent 15-lipoxygenase inhibitors. |
Mashhad University of Medical Sciences |
19848434 |
27 |
Using enzyme assays to evaluate the structure and bioactivity of sponge-derived meroterpenes. |
University of California Santa Cruz |
12608855 |
25 |
Exploring sponge-derived terpenoids for their potency and selectivity against 12-human, 15-human, and 15-soybean lipoxygenases. |
University of California Santa Cruz |
17502145 |
18 |
Inhibition of IGF-1R and lipoxygenase by nordihydroguaiaretic acid (NDGA) analogs. |
San Francisco State University |
17826100 |
18 |
Discovery of platelet-type 12-human lipoxygenase selective inhibitors by high-throughput screening of structurally diverse libraries. |
University of California |
15566311 |
6 |
Discovery of novel phenolic antioxidants as inhibitors of vascular cell adhesion molecule-1 expression for use in chronic inflammatory diseases. |
Atherogenics |
12036375 |
25 |
Structure-activity relationship studies of nordihydroguaiaretic acid inhibitors toward soybean, 12-human, and 15-human lipoxygenase. |
University of California |
21868137 |
69 |
Pyrazol-3-propanoic acid derivatives as novel inhibitors of leukotriene biosynthesis in human neutrophils. |
Gazi University |
21739938 |
72 |
Discovery of potent and selective inhibitors of human platelet-type 12- lipoxygenase. |
National Human Genome Research Institute |
21696952 |
41 |
Pyrazole-based sulfonamide and sulfamides as potent inhibitors of mammalian 15-lipoxygenase. |
Bristol-Myers Squibb Research and Development |
21044840 |
47 |
Potent and selective 5-LO inhibitor bearing benzothiophene pharmacophore: discovery of MK-5286. |
Merck Frosst Centre For Therapeutic Research |
20866075 |
87 |
Discovery of potent and selective inhibitors of human reticulocyte 15-lipoxygenase-1. |
National Human Genome Research Institute |
7494145 |
5 |
Enzyme Inhibitors: New and Known Polybrominated Phenols and Diphenyl Ethers from Four Indo-Pacific Dysidea Sponges |
TBA |
| 19 |
Catechol based inhibitors of 15-lipoxygenase |
TBA |
| 21 |
1-Phenyl-[2H]-tetrahydropyridazin-3-one, A-53612, a selective orally active 5-lipoxygenase inhibitor |
TBA |
15332838 |
2 |
An analysis of phakellin and oroidin structures stimulated by further study of an Agelas sponge. |
University of California |
17869117 |
153 |
Structure-activity relationship studies of flavonoids as potent inhibitors of human platelet 12-hLO, reticulocyte 15-hLO-1, and prostate epithelial 15-hLO-2. |
Universidad De Santiago De Chile |
16480270 |
40 |
Novel human lipoxygenase inhibitors discovered using virtual screening with homology models. |
University of California |
15267244 |
40 |
Probing the activity differences of simple and complex brominated aryl compounds against 15-soybean, 15-human, and 12-human lipoxygenase. |
University of California |
14684299 |
2 |
A facile synthesis of 1-ethoxy-4-cyano-5-ethoxycarbonyl-3H-azuleno[1,2-c]pyran-3-one, a selective 15-lipoxygenase inhibitor. |
Tamkang University |
12852938 |
7 |
Effect of catechol derivatives on cell growth and lipoxygenase activity. |
Aston University |
8831760 |
108 |
5-Lipoxygenase inhibitors: synthesis and structure-activity relationships of a series of 1-aryl-2H,4H-tetrahydro-1,2,4-triazin-3-ones. |
Abbott Laboratories |
2542553 |
31 |
Synthesis and structure-activity relationships of a novel class of 5-lipoxygenase inhibitors. 2-(Phenylmethyl)-4-hydroxy-3,5-dialkylbenzofurans: the development of L-656,224. |
Merck Frosst Canada |