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40 articles for thisTarget


The following articles (labelled with PubMed ID or TBD) are for your review
PMIDDataArticle TitleOrganization
28318946 3 Easy and rapid preparation of benzoylhydrazides and their diazene derivatives as inhibitors of 15-lipoxygenase.EBI Universidad De Chile
27802026 1 Magnetic Microbead Affinity Selection Screening (MagMASS) of Botanical Extracts for Inhibitors of 15-Lipoxygenase.EBI University of Illinois At Chicago
27477687 21 Design of a novel thiophene inhibitor of 15-lipoxygenase-1 with both anti-inflammatory and neuroprotective properties.EBI University of Groningen
26290290 4 Discovery of Novel 15-Lipoxygenase Activators To Shift the Human Arachidonic Acid Metabolic Network toward Inflammation Resolution.EBI University of California San Diego
26899595 32 A potent and selective inhibitor targeting human and murine 12/15-LOX.EBI University of California
26331552 37 Rational Development of a Potent 15-Lipoxygenase-1 Inhibitor with in Vitro and ex Vivo Anti-inflammatory Properties.EBI University of Groningen
26037322 100 3-Substituted pyrazoles and 4-substituted triazoles as inhibitors of human 15-lipoxygenase-1.EBI Uppsala University
26037319 14 N-Substituted pyrazole-3-carboxamides as inhibitors of human 15-lipoxygenase.EBI Uppsala University
24924423 21 Inhibitory and mechanistic investigations of oxo-lipids with human lipoxygenase isozymes.EBI University of California
25462262 98 Development and evaluation of ST-1829 based on 5-benzylidene-2-phenylthiazolones as promising agent for anti-leukotriene therapy.EBI Goethe-University Frankfurt
24920381 77 SAR studies on curcumin's pro-inflammatory targets: discovery of prenylated pyrazolocurcuminoids as potent and selective novel inhibitors of 5-lipoxygenase.EBI University Jena
24871899 31 Further studies on ethyl 5-hydroxy-indole-3-carboxylate scaffold: design, synthesis and evaluation of 2-phenylthiomethyl-indole derivatives as efficient inhibitors of human 5-lipoxygenase.EBI University of Naples
24684213 56 Potent and selective inhibitors of human reticulocyte 12/15-lipoxygenase as anti-stroke therapies.EBI Harvard Medical School
24393039 97 Synthesis and structure-activity relationship studies of 4-((2-hydroxy-3-methoxybenzyl)amino)benzenesulfonamide derivatives as potent and selective inhibitors of 12-lipoxygenase.EBI National Institutes of Health
23871907 64 Discovery and biological evaluation of novel 1,4-benzoquinone and related resorcinol derivatives that inhibit 5-lipoxygenase.EBI University of Salerno
23047230 13 Synthesis and SAR studies of mono O-prenylated coumarins as potent 15-lipoxygenase inhibitors.EBI Mashhad University of Medical Sciences
19848434 27 Using enzyme assays to evaluate the structure and bioactivity of sponge-derived meroterpenes.EBI University of California Santa Cruz
12608855 25 Exploring sponge-derived terpenoids for their potency and selectivity against 12-human, 15-human, and 15-soybean lipoxygenases.EBI University of California Santa Cruz
17502145 18 Inhibition of IGF-1R and lipoxygenase by nordihydroguaiaretic acid (NDGA) analogs.EBI San Francisco State University
17826100 18 Discovery of platelet-type 12-human lipoxygenase selective inhibitors by high-throughput screening of structurally diverse libraries.EBI University of California
15566311 6 Discovery of novel phenolic antioxidants as inhibitors of vascular cell adhesion molecule-1 expression for use in chronic inflammatory diseases.EBI Atherogenics
12036375 25 Structure-activity relationship studies of nordihydroguaiaretic acid inhibitors toward soybean, 12-human, and 15-human lipoxygenase.EBI University of California
21868137 69 Pyrazol-3-propanoic acid derivatives as novel inhibitors of leukotriene biosynthesis in human neutrophils.EBI Gazi University
21739938 72 Discovery of potent and selective inhibitors of human platelet-type 12- lipoxygenase.EBI National Human Genome Research Institute
21696952 41 Pyrazole-based sulfonamide and sulfamides as potent inhibitors of mammalian 15-lipoxygenase.EBI Bristol-Myers Squibb Research and Development
21044840 47 Potent and selective 5-LO inhibitor bearing benzothiophene pharmacophore: discovery of MK-5286.EBI Merck Frosst Centre For Therapeutic Research
20866075 87 Discovery of potent and selective inhibitors of human reticulocyte 15-lipoxygenase-1.EBI National Human Genome Research Institute
7494145 5 Enzyme Inhibitors: New and Known Polybrominated Phenols and Diphenyl Ethers from Four Indo-Pacific Dysidea SpongesEBI TBA
 19 Catechol based inhibitors of 15-lipoxygenaseEBI TBA
 21 1-Phenyl-[2H]-tetrahydropyridazin-3-one, A-53612, a selective orally active 5-lipoxygenase inhibitorEBI TBA
15332838 2 An analysis of phakellin and oroidin structures stimulated by further study of an Agelas sponge.EBI University of California
17869117 153 Structure-activity relationship studies of flavonoids as potent inhibitors of human platelet 12-hLO, reticulocyte 15-hLO-1, and prostate epithelial 15-hLO-2.EBI Universidad De Santiago De Chile
16480270 40 Novel human lipoxygenase inhibitors discovered using virtual screening with homology models.EBI University of California
15267244 40 Probing the activity differences of simple and complex brominated aryl compounds against 15-soybean, 15-human, and 12-human lipoxygenase.EBI University of California
14684299 2 A facile synthesis of 1-ethoxy-4-cyano-5-ethoxycarbonyl-3H-azuleno[1,2-c]pyran-3-one, a selective 15-lipoxygenase inhibitor.EBI Tamkang University
12852938 7 Effect of catechol derivatives on cell growth and lipoxygenase activity.EBI Aston University
8831760 108 5-Lipoxygenase inhibitors: synthesis and structure-activity relationships of a series of 1-aryl-2H,4H-tetrahydro-1,2,4-triazin-3-ones.EBI Abbott Laboratories
2542553 31 Synthesis and structure-activity relationships of a novel class of 5-lipoxygenase inhibitors. 2-(Phenylmethyl)-4-hydroxy-3,5-dialkylbenzofurans: the development of L-656,224.EBI Merck Frosst Canada