The following articles (labelled with PubMed ID or TBD) are for your review
| PMID | Data | Article Title | Organization |
|---|
| 28324649 |
99 |
Sulfonamides as Selective Na |
Amgen |
| 28287723 |
73 |
Sulfonamides as Selective Na |
Amgen |
| 2579237 |
115 |
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs. |
TBA |
| 27994738 |
50 |
Sulfonamides as Selective Na |
Amgen |
| 26985315 |
49 |
Discovery of Aryl Sulfonamides as Isoform-Selective Inhibitors of NaV1.7 with Efficacy in Rodent Pain Models. |
Xenon Pharmaceuticals |
| 25927480 |
36 |
Voltage-Gated Sodium Channels: Structure, Function, Pharmacology, and Clinical Indications. |
Merck Research Laboratories |
| 26101568 |
51 |
Discovery and Optimization of Selective Nav1.8 Modulator Series That Demonstrate Efficacy in Preclinical Models of Pain. |
Pfizer |
| 21300721 |
90 |
Simulation of multiple ion channel block provides improved early prediction of compounds' clinical torsadogenic risk. |
University Of Oxford |
| 25658507 |
218 |
Engineering potent and selective analogues of GpTx-1, a tarantula venom peptide antagonist of the Na(V)1.7 sodium channel. |
Amgen |
| 24601592 |
48 |
Imidazol-1-ylethylindazole voltage-gated sodium channel ligands are neuroprotective during optic neuritis in a mouse model of multiple sclerosis. |
University College London |
| 23121096 |
86 |
Ion channels as therapeutic targets: a drug discovery perspective. |
Pfizer |
| 17483457 |
58 |
A-803467, a potent and selective Nav1.8 sodium channel blocker, attenuates neuropathic and inflammatory pain in the rat. |
Abbott Laboratories |
| 16134928 |
34 |
Joys of molecules. 2. Endeavors in chemical biology and medicinal chemistry. |
The Scripps Research Institute |
| 11229757 |
5 |
Identification and characterization of a potential ischemia-selective N-methyl-D-aspartate (NMDA) receptor ion-channel blocker, CNS 5788. |
Cambridge Neuroscience |
| | 15 |
Batrachotoxin binding site antagonists |
TBA |
| 21634377 |
73 |
Identification of a potent, state-dependent inhibitor of Nav1.7 with oral efficacy in the formalin model of persistent pain. |
Amgen |
| 17489575 |
7 |
Sodium channel blockers. |
Purdue Pharma |
| 3016269 |
31 |
Anticonvulsant activity of piperidinol and (dialkylamino)alkanol esters. |
TBA |
| 7932531 |
55 |
Inhibitors of HIV-1 proteinase containing 2-heterosubstituted 4-amino-3-hydroxy-5-phenylpentanoic acid: synthesis, enzyme inhibition, and antiviral activity. |
Sandoz Forschungsinstitut Ges.M.B.H. |
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