10 articles for thisTarget

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The following articles (labelled with PubMed ID or TBD) are for your review

PMID	Data	Article Title	Organization
25782742	76	trans-(3S,4S)-Disubstituted pyrrolidines as inhibitors of the human aspartyl protease renin. Part I: prime site exploration using an amino linker.	Novartis Pharma
25754490	44	trans-3,4-Disubstituted pyrrolidines as inhibitors of the human aspartyl protease renin. Part II: prime site exploration using an oxygen linker.	Novartis Pharma
25050166	58	Structure-based design of substituted piperidines as a new class of highly efficacious oral direct Renin inhibitors.	Novartis Institutes For Biomedical Research
23425156	24	The discovery of novel potent trans-3,4-disubstituted pyrrolidine inhibitors of the human aspartic protease renin from in silico three-dimensional (3D) pharmacophore searches.	Novartis Pharma
23360239	19	A novel class of oral direct renin inhibitors: highly potent 3,5-disubstituted piperidines bearing a tricyclic p3-p1 pharmacophore.	Novartis Pharma
2002469	80	Renin inhibitors containing conformationally restricted P1-P1' dipeptide mimetics.	Merck Sharp and Dohme Research Laboratories
3783611	55	Inhibition of cathepsin D by substrate analogues containing statine and by analogues of pepstatin.	TBA
	22	Novel pseudosymmetric inhibitors of HIV-1 protease	TBA
8410992	35	Renin inhibitors containing a pyridyl amino diol derived C-terminus.	Hoechst
8410973	75	Specificity in the binding of inhibitors to the active site of human/primate aspartic proteinases: analysis of P2-P1-P1'-P2' variation.	University of Florida