PMID | Data | Article Title | Organization |
---|---|---|---|
26814576 | 146 | New 4-Functionalized Glutamate Analogues Are Selective Agonists at Metabotropic Glutamate Receptor Subtype 2 or Selective Agonists at Metabotropic Glutamate Receptor Group III. | University of Copenhagen |
26684851 | 86 | Preliminary investigation of 6,7-dihydropyrazolo[1,5-a]pyrazin-4-one derivatives as a novel series of mGlu5 receptor positive allosteric modulators with efficacy in preclinical models of schizophrenia. | Janssen Pharmaceutica |
25958247 | 22 | Synthesis and studies on the mGluR agonist activity of FAP4 stereoisomers. | Univ. Rouen |
24914612 | 36 | Tetrahydronaphthyridine and dihydronaphthyridinone ethers as positive allosteric modulators of the metabotropic glutamate receptor 5 (mGlu5). | Vanderbilt University Medical Center |
24735492 | 98 | Design and synthesis of systemically active metabotropic glutamate subtype-2 and -3 (mGlu2/3) receptor positive allosteric modulators (PAMs): pharmacological characterization and assessment in a rat model of cocaine dependence. | Sanford-Burnham Medical Research Institute |
23009245 | 53 | Orally active metabotropic glutamate subtype 2 receptor positive allosteric modulators: structure-activity relationships and assessment in a rat model of nicotine dependence. | Sanford-Burnham Medical Research Institute |
20218620 | 81 | A virtual screening hit reveals new possibilities for developing group III metabotropic glutamate receptor agonists. | Universite Paris Descartes |
17350267 | 48 | Synthesis and preliminary pharmacological evaluation of the four stereoisomers of (2S)-2-(2'-phosphono-3'-phenylcyclopropyl)glycine, the first class of 3'-substituted trans C1'-2'-2-(2'-phosphonocyclopropyl)glycines. | Universit£ |
16213710 | 32 | Synthesis and preliminary biological evaluation of (2S,1'R,2'S)- and (2S,1'S,2'R)-2-(2'-phosphonocyclopropyl)glycines, two novel conformationally constrained l-AP4 analogues. | Universit£ |
9357538 | 38 | (S)-homo-AMPA, a specific agonist at the mGlu6 subtype of metabotropic glutamic acid receptors. | Royal Danish School of Pharmacy |
7738999 | 88 | Metabotropic glutamate receptors: novel targets for drug development. | Cns Research |
11459661 | 41 | Synthesis of N(1)-substituted analogues of (2R,4R)-4-amino-pyrrolidine-2,4-dicarboxylic acid as agonists, partial agonists, and antagonists of group II metabotropic glutamate receptors. | Georgetown University Medical Center |
6 | Synthesis and biological activity of cyclic analogues of MPPG and MCPG as metabotropic glutamate receptor antagonists | TBA | |
15 | Synthesis, molecular modeling, and biology of the 1-benzyl derivative of APDC-an apparent mGluR6 selective ligand | TBA | |
17722902 | 16 | L-(+)-2-Amino-4-thiophosphonobutyric acid (L-thioAP4), a new potent agonist of group III metabotropic glutamate receptors: increased distal acidity affords enhanced potency. | Université |
16828551 | 12 | Design and synthesis of APTCs (aminopyrrolidinetricarboxylic acids): identification of a new group III metabotropic glutamate receptor selective agonist. | Faust Pharmaceuticals |
15317467 | 105 | Synthesis, in vitro pharmacology, structure-activity relationships, and pharmacokinetics of 3-alkoxy-2-amino-6-fluorobicyclo[3.1.0]hexane-2,6-dicarboxylic acid derivatives as potent and selective group II metabotropic glutamate receptor antagonists. | Taisho Pharmaceutical |
14711315 | 72 | (2S,1'S,2'R,3'R)-2-(2'-Carboxy-3'-hydroxymethylcyclopropyl) glycine is a highly potent group 2 and 3 metabotropic glutamate receptor agonist with oral activity. | Eli Lilly |
9871596 | 4 | alpha-substituted quisqualic acid analogs: new metabotropic glutamate receptor group II selective antagonists. | Georgetown University Medical Center |