BDBM119440 BDBM119696::US8685986, 15
SMILES: ONC(=O)c1ccc(CNC(=O)c2[nH]c(cc2-c2ccoc2)-c2ccc(O)cc2)cc1
InChI Key: InChIKey=OUFJXJJAONPLLU-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human)) | BDBM119440 (BDBM119696 | US8685986, 15) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Similars | US Patent | 9.40 | -11.1 | n/a | n/a | n/a | n/a | n/a | 6.0 | 30 |
Ube Industries, Ltd. US Patent | Assay Description Measurement of EP2 receptor binding affinity was carried out according to the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285 (... | US Patent US8685986 (2014) BindingDB Entry DOI: 10.7270/Q28S4NK1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone deacetylase 2 (Homo sapiens (Human)) | BDBM119440 (BDBM119696 | US8685986, 15) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 144 | n/a | n/a | n/a | n/a | n/a | 30 |
Universidad del País Vasco; Ikerschem, S.L. US Patent | Assay Description The reactions were carried out in a 96-well microplate for fluorometry in a 50 μl reaction volume. After the deacetylation reaction, Fluor-de-Ly... | US Patent US8685992 (2014) BindingDB Entry DOI: 10.7270/Q2CJ8C4X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone deacetylase 3 (Homo sapiens (Human)) | BDBM119440 (BDBM119696 | US8685986, 15) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 46.1 | n/a | n/a | n/a | n/a | n/a | 30 |
Universidad del País Vasco; Ikerschem, S.L. US Patent | Assay Description The reactions were carried out in a 96-well microplate for fluorometry in a 50 μl reaction volume. After the deacetylation reaction, Fluor-de-Ly... | US Patent US8685992 (2014) BindingDB Entry DOI: 10.7270/Q2CJ8C4X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone deacetylase 4 (Homo sapiens (Human)) | BDBM119440 (BDBM119696 | US8685986, 15) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 338 | n/a | n/a | n/a | n/a | n/a | 30 |
Universidad del País Vasco; Ikerschem, S.L. US Patent | Assay Description The reactions were carried out in a 96-well microplate for fluorometry in a 50 μl reaction volume. After the deacetylation reaction, Fluor-de-Ly... | US Patent US8685992 (2014) BindingDB Entry DOI: 10.7270/Q2CJ8C4X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone deacetylase 11 (Homo sapiens (Human)) | BDBM119440 (BDBM119696 | US8685986, 15) | NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 72 | n/a | n/a | n/a | n/a | n/a | 30 |
Universidad del País Vasco; Ikerschem, S.L. US Patent | Assay Description The reactions were carried out in a 96-well microplate for fluorometry in a 50 μl reaction volume. After the deacetylation reaction, Fluor-de-Ly... | US Patent US8685992 (2014) BindingDB Entry DOI: 10.7270/Q2CJ8C4X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone deacetylase 6 (Homo sapiens (Human)) | BDBM119440 (BDBM119696 | US8685986, 15) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.700 | n/a | n/a | n/a | n/a | n/a | 30 |
Universidad del País Vasco; Ikerschem, S.L. US Patent | Assay Description The reactions were carried out in a 96-well microplate for fluorometry in a 50 μl reaction volume. After the deacetylation reaction, Fluor-de-Ly... | US Patent US8685992 (2014) BindingDB Entry DOI: 10.7270/Q2CJ8C4X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone deacetylase 7 (Homo sapiens (Human)) | BDBM119440 (BDBM119696 | US8685986, 15) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 178 | n/a | n/a | n/a | n/a | n/a | 30 |
Universidad del País Vasco; Ikerschem, S.L. US Patent | Assay Description The reactions were carried out in a 96-well microplate for fluorometry in a 50 μl reaction volume. After the deacetylation reaction, Fluor-de-Ly... | US Patent US8685992 (2014) BindingDB Entry DOI: 10.7270/Q2CJ8C4X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone deacetylase 8 (Homo sapiens (Human)) | BDBM119440 (BDBM119696 | US8685986, 15) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 74.8 | n/a | n/a | n/a | n/a | n/a | 30 |
Universidad del País Vasco; Ikerschem, S.L. US Patent | Assay Description The reactions were carried out in a 96-well microplate for fluorometry in a 50 μl reaction volume. After the deacetylation reaction, Fluor-de-Ly... | US Patent US8685992 (2014) BindingDB Entry DOI: 10.7270/Q2CJ8C4X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone deacetylase 9 (Homo sapiens (Human)) | BDBM119440 (BDBM119696 | US8685986, 15) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 59 | n/a | n/a | n/a | n/a | n/a | 30 |
Universidad del País Vasco; Ikerschem, S.L. US Patent | Assay Description The reactions were carried out in a 96-well microplate for fluorometry in a 50 μl reaction volume. After the deacetylation reaction, Fluor-de-Ly... | US Patent US8685992 (2014) BindingDB Entry DOI: 10.7270/Q2CJ8C4X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polyamine deacetylase HDAC10 (Homo sapiens (Human)) | BDBM119440 (BDBM119696 | US8685986, 15) | NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 35 | n/a | n/a | n/a | n/a | n/a | 30 |
Universidad del País Vasco; Ikerschem, S.L. US Patent | Assay Description The reactions were carried out in a 96-well microplate for fluorometry in a 50 μl reaction volume. After the deacetylation reaction, Fluor-de-Ly... | US Patent US8685992 (2014) BindingDB Entry DOI: 10.7270/Q2CJ8C4X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone deacetylase 1 (Homo sapiens (Human)) | BDBM119440 (BDBM119696 | US8685986, 15) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 49.9 | n/a | n/a | n/a | n/a | n/a | 30 |
Universidad del País Vasco; Ikerschem, S.L. US Patent | Assay Description The reactions were carried out in a 96-well microplate for fluorometry in a 50 μl reaction volume. After the deacetylation reaction, Fluor-de-Ly... | US Patent US8685992 (2014) BindingDB Entry DOI: 10.7270/Q2CJ8C4X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone deacetylase 5 (Homo sapiens (Human)) | BDBM119440 (BDBM119696 | US8685986, 15) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 60 | n/a | n/a | n/a | n/a | n/a | 30 |
Universidad del País Vasco; Ikerschem, S.L. US Patent | Assay Description The reactions were carried out in a 96-well microplate for fluorometry in a 50 μl reaction volume. After the deacetylation reaction, Fluor-de-Ly... | US Patent US8685992 (2014) BindingDB Entry DOI: 10.7270/Q2CJ8C4X | |||||||||||
More data for this Ligand-Target Pair |