BDBM142598 US10238658, Example Reference::US10813932, Reference Compound::US8933228, Ref 2::US9242960, 1::US9249125, Reference Compound::US9701670, Reference Compound::US9724347, Example Reference::US9993478, Example Reference
SMILES: COCC(=O)Nc1cc(Oc2ccc(NC(=O)Nc3cc(nn3-c3ccc(C)cc3)C(C)(C)C)c3ccccc23)ccn1
InChI Key: InChIKey=AVUUHIYJPTWYNX-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Mitogen-activated protein kinase 14 (Homo sapiens (Human)) | BDBM142598 (US10238658, Example Reference | US10813932, Refere...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
Respivert, Ltd. US Patent | Assay Description The enzyme inhibitory activity of test compounds was determined by fluorescence resonance energy transfer (FRET) using synthetic peptides labelled wi... | US Patent US8933228 (2015) BindingDB Entry DOI: 10.7270/Q2RV0MDW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glycogen synthase kinase-3 beta (Homo sapiens (Human)) | BDBM142598 (US10238658, Example Reference | US10813932, Refere...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | n/a | 24 | n/a | n/a | n/a | n/a | n/a |
Respivert Limited US Patent | US Patent US10813932 (2020) | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase HCK (Homo sapiens (Human)) | BDBM142598 (US10238658, Example Reference | US10813932, Refere...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
Respivert, Ltd. US Patent | Assay Description The enzyme inhibitory activity of test compounds was determined by fluorescence resonance energy transfer (FRET) using synthetic peptides labelled wi... | US Patent US8933228 (2015) BindingDB Entry DOI: 10.7270/Q2RV0MDW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human)) | BDBM142598 (US10238658, Example Reference | US10813932, Refere...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
Respivert, Ltd. US Patent | Assay Description The enzyme inhibitory activity of test compounds was determined by fluorescence resonance energy transfer (FRET) using synthetic peptides labelled wi... | US Patent US8933228 (2015) BindingDB Entry DOI: 10.7270/Q2RV0MDW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human)) | BDBM142598 (US10238658, Example Reference | US10813932, Refere...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
RESPIVERT LIMITED; TOPIVERT PHARMA LIMITED US Patent | Assay Description The inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), are evaluated in a similar fashion to that descri... | US Patent US9249125 (2016) BindingDB Entry DOI: 10.7270/Q2CN72QG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase SYK (Homo sapiens (Human)) | BDBM142598 (US10238658, Example Reference | US10813932, Refere...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 42 | n/a | n/a | n/a | n/a | n/a | n/a |
RESPIVERT LIMITED; TOPIVERT PHARMA LIMITED US Patent | Assay Description The inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), are evaluated in a similar fashion to that descri... | US Patent US9249125 (2016) BindingDB Entry DOI: 10.7270/Q2CN72QG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glycogen synthase kinase-3 (Homo sapiens (Human)) | BDBM142598 (US10238658, Example Reference | US10813932, Refere...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 45 | n/a | n/a | n/a | n/a | n/a | n/a |
RESPIVERT LIMITED; TOPIVERT PHARMA LIMITED US Patent | Assay Description The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level ... | US Patent US9249125 (2016) BindingDB Entry DOI: 10.7270/Q2CN72QG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 14 (Homo sapiens (Human)) | BDBM142598 (US10238658, Example Reference | US10813932, Refere...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | 25 |
Respivert, Ltd. US Patent | Assay Description The enzyme inhibitory activity of compound was determined by FRET using synthetic peptides labelled with both donor and acceptor fluorophores (Z-LY... | US Patent US9242960 (2016) BindingDB Entry DOI: 10.7270/Q20K27C2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 12 (Homo sapiens (Human)) | BDBM142598 (US10238658, Example Reference | US10813932, Refere...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 344 | n/a | n/a | n/a | n/a | n/a | 25 |
Respivert, Ltd. US Patent | Assay Description The enzyme inhibitory activity of compound was determined by FRET using synthetic peptides labelled with both donor and acceptor fluorophores (Z-LY... | US Patent US9242960 (2016) BindingDB Entry DOI: 10.7270/Q20K27C2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 14 (Homo sapiens (Human)) | BDBM142598 (US10238658, Example Reference | US10813932, Refere...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
RESPIVERT LIMITED; TOPIVERT PHARMA LIMITED US Patent | Assay Description The inhibitory activities of test compounds against the p38 MAPKα isoform (MAPK14: Invitrogen), are evaluated indirectly by determining the l... | US Patent US9249125 (2016) BindingDB Entry DOI: 10.7270/Q2CN72QG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 14 (Homo sapiens (Human)) | BDBM142598 (US10238658, Example Reference | US10813932, Refere...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
RESPIVERT LIMITED; TOPIVERT PHARMA LIMITED US Patent | Assay Description The inhibitory activities of test compounds against the p38 MAPKα isoform (MAPK14: Invitrogen), are evaluated indirectly by determining the leve... | US Patent US9701670 (2017) BindingDB Entry DOI: 10.7270/Q2JM2CP2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human)) | BDBM142598 (US10238658, Example Reference | US10813932, Refere...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
RESPIVERT LIMITED; TOPIVERT PHARMA LIMITED US Patent | Assay Description The inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), are evaluated in a similar fashion to that descri... | US Patent US9701670 (2017) BindingDB Entry DOI: 10.7270/Q2JM2CP2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase SYK (Homo sapiens (Human)) | BDBM142598 (US10238658, Example Reference | US10813932, Refere...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 42 | n/a | n/a | n/a | n/a | n/a | n/a |
RESPIVERT LIMITED; TOPIVERT PHARMA LIMITED US Patent | Assay Description The inhibitory activities of compounds of the invention against Syk enzymes (Invitrogen), are evaluated in a similar fashion to that described herein... | US Patent US9701670 (2017) BindingDB Entry DOI: 10.7270/Q2JM2CP2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glycogen synthase kinase-3 (Homo sapiens (Human)) | BDBM142598 (US10238658, Example Reference | US10813932, Refere...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 45 | n/a | n/a | n/a | n/a | n/a | n/a |
RESPIVERT LIMITED; TOPIVERT PHARMA LIMITED US Patent | Assay Description The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level o... | US Patent US9701670 (2017) BindingDB Entry DOI: 10.7270/Q2JM2CP2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2A (Homo sapiens (Human)) | BDBM142598 (US10238658, Example Reference | US10813932, Refere...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
Respivert, Ltd. US Patent | Assay Description The inhibitory activities of test compounds against the p38 MAPKα isoform (MAPK14: Invitrogen), were evaluated indirectly by determining the lev... | US Patent US9724347 (2017) BindingDB Entry DOI: 10.7270/Q2MC923K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 12 (Homo sapiens (Human)) | BDBM142598 (US10238658, Example Reference | US10813932, Refere...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 344 | n/a | n/a | n/a | n/a | n/a | n/a |
Respivert, Ltd. US Patent | Assay Description The inhibitory activities of compounds of the invention against p38MAPKγ (MAPK12: Invitrogen), were evaluated in a similar fashion to that descr... | US Patent US9724347 (2017) BindingDB Entry DOI: 10.7270/Q2MC923K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glycogen synthase kinase-3 (Homo sapiens (Human)) | BDBM142598 (US10238658, Example Reference | US10813932, Refere...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 45 | n/a | n/a | n/a | n/a | n/a | n/a |
Respivert, Ltd. US Patent | Assay Description The GSK3-α protein (500 ng/mL, 2.5 μL) was mixed with the test compound (2.5 μL at either 4 μg/mL, 0.4 μg/mL, 0.04 μg/m... | US Patent US9724347 (2017) BindingDB Entry DOI: 10.7270/Q2MC923K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human)) | BDBM142598 (US10238658, Example Reference | US10813932, Refere...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
Respivert, Ltd. US Patent | Assay Description The inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), were evaluated in a similar fashion to that descr... | US Patent US9724347 (2017) BindingDB Entry DOI: 10.7270/Q2MC923K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase SYK (Homo sapiens (Human)) | BDBM142598 (US10238658, Example Reference | US10813932, Refere...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 42 | n/a | n/a | n/a | n/a | n/a | n/a |
Respivert, Ltd. US Patent | Assay Description The inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), were evaluated in a similar fashion to that descr... | US Patent US9724347 (2017) BindingDB Entry DOI: 10.7270/Q2MC923K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2A (Homo sapiens (Human)) | BDBM142598 (US10238658, Example Reference | US10813932, Refere...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a |
Respivert, Ltd. US Patent | Assay Description The inhibitory activities of test compounds against the p38 MAPKα isoform (MAPK14: Invitrogen), were evaluated indirectly by determining the lev... | US Patent US9724347 (2017) BindingDB Entry DOI: 10.7270/Q2MC923K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 12 (Homo sapiens (Human)) | BDBM142598 (US10238658, Example Reference | US10813932, Refere...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a |
Respivert, Ltd. US Patent | Assay Description The inhibitory activities of compounds of the invention against p38MAPKγ (MAPK12: Invitrogen), were evaluated in a similar fashion to that descr... | US Patent US9724347 (2017) BindingDB Entry DOI: 10.7270/Q2MC923K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase HCK (Homo sapiens (Human)) | BDBM142598 (US10238658, Example Reference | US10813932, Refere...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a |
Respivert, Ltd. US Patent | Assay Description The inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), were evaluated in a similar fashion to that descr... | US Patent US9724347 (2017) BindingDB Entry DOI: 10.7270/Q2MC923K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human)) | BDBM142598 (US10238658, Example Reference | US10813932, Refere...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a |
Respivert, Ltd. US Patent | Assay Description The inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), were evaluated in a similar fashion to that descr... | US Patent US9724347 (2017) BindingDB Entry DOI: 10.7270/Q2MC923K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase SYK (Homo sapiens (Human)) | BDBM142598 (US10238658, Example Reference | US10813932, Refere...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | n/a | 9 | n/a | n/a | n/a | n/a | n/a |
Respivert, Ltd. US Patent | Assay Description The inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), were evaluated in a similar fashion to that descr... | US Patent US9724347 (2017) BindingDB Entry DOI: 10.7270/Q2MC923K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glycogen synthase kinase-3 (Homo sapiens (Human)) | BDBM142598 (US10238658, Example Reference | US10813932, Refere...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | n/a | 180 | n/a | n/a | n/a | n/a | n/a |
Respivert, Ltd. US Patent | Assay Description The GSK3-α protein (500 ng/mL, 2.5 μL) was mixed with the test compound (2.5 μL at either 4 μg/mL, 0.4 μg/mL, 0.04 μg/m... | US Patent US9724347 (2017) BindingDB Entry DOI: 10.7270/Q2MC923K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glycogen synthase kinase-3 beta (Homo sapiens (Human)) | BDBM142598 (US10238658, Example Reference | US10813932, Refere...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | n/a | 24 | n/a | n/a | n/a | n/a | n/a |
Respivert, Ltd. US Patent | Assay Description The GSK3-α protein (500 ng/mL, 2.5 μL) was mixed with the test compound (2.5 μL at either 4 μg/mL, 0.4 μg/mL, 0.04 μg/m... | US Patent US9724347 (2017) BindingDB Entry DOI: 10.7270/Q2MC923K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 12 (Homo sapiens (Human)) | BDBM142598 (US10238658, Example Reference | US10813932, Refere...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 344 | n/a | n/a | n/a | n/a | n/a | n/a |
Nerviano Medical Sciences Srl | Assay Description p38 MAPKγ: The enzyme inhibitory activities of compounds disclosed herein were determined by FRET using synthetic peptides labelled with both do... | J Med Chem 52: 5152-63 (2009) BindingDB Entry DOI: 10.7270/Q2125W1Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glycogen synthase kinase-3 (Homo sapiens (Human)) | BDBM142598 (US10238658, Example Reference | US10813932, Refere...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 45 | n/a | n/a | n/a | n/a | n/a | n/a |
Nerviano Medical Sciences Srl | Assay Description GSK 3α: The enzyme inhibitory activities of compounds disclosed herein were determined by FRET using synthetic peptides labelled with both donor... | J Med Chem 52: 5152-63 (2009) BindingDB Entry DOI: 10.7270/Q2125W1Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 14 (Homo sapiens (Human)) | BDBM142598 (US10238658, Example Reference | US10813932, Refere...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
Nerviano Medical Sciences Srl | Assay Description p38 MAPKα: The enzyme inhibitory activities of compounds disclosed herein were determined by FRET using synthetic peptides labelled with both do... | J Med Chem 52: 5152-63 (2009) BindingDB Entry DOI: 10.7270/Q2125W1Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 12 (Homo sapiens (Human)) | BDBM142598 (US10238658, Example Reference | US10813932, Refere...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 344 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer HealthCare Pharmaceuticals Corporation | Assay Description The inhibitory activities of compounds of the invention against p38MAPKγ (MAPK12: Invitrogen), were evaluated in a similar fashion to that descr... | J Med Chem 50: 984-1000 (2007) BindingDB Entry DOI: 10.7270/Q2PG1V1T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 14 (Homo sapiens (Human)) | BDBM142598 (US10238658, Example Reference | US10813932, Refere...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer HealthCare Pharmaceuticals Corporation | Assay Description The inhibitory activities of test compounds against the p38 MAPKα isoform (MAPK14: Invitrogen), were evaluated indirectly by determining the lev... | J Med Chem 50: 984-1000 (2007) BindingDB Entry DOI: 10.7270/Q2PG1V1T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glycogen synthase kinase-3 (Homo sapiens (Human)) | BDBM142598 (US10238658, Example Reference | US10813932, Refere...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 45 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer HealthCare Pharmaceuticals Corporation | Assay Description The inhibitory activities of test compounds against the GSK 3α enzyme isoform (Invitrogen), were evaluated by determining the level of activatio... | J Med Chem 50: 984-1000 (2007) BindingDB Entry DOI: 10.7270/Q2PG1V1T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human)) | BDBM142598 (US10238658, Example Reference | US10813932, Refere...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer HealthCare Pharmaceuticals Corporation | Assay Description The inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), were evaluated in a similar fashion to that descr... | J Med Chem 50: 984-1000 (2007) BindingDB Entry DOI: 10.7270/Q2PG1V1T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase SYK (Homo sapiens (Human)) | BDBM142598 (US10238658, Example Reference | US10813932, Refere...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 42 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer HealthCare Pharmaceuticals Corporation | Assay Description The inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), were evaluated in a similar fashion to that descr... | J Med Chem 50: 984-1000 (2007) BindingDB Entry DOI: 10.7270/Q2PG1V1T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 14 (Homo sapiens (Human)) | BDBM142598 (US10238658, Example Reference | US10813932, Refere...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a |
Bayer HealthCare Pharmaceuticals Corporation | Assay Description The inhibitory activities of test compounds against the p38 MAPKα isoform (MAPK14: Invitrogen), were evaluated indirectly by determining the lev... | J Med Chem 50: 984-1000 (2007) BindingDB Entry DOI: 10.7270/Q2PG1V1T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 12 (Homo sapiens (Human)) | BDBM142598 (US10238658, Example Reference | US10813932, Refere...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a |
Bayer HealthCare Pharmaceuticals Corporation | Assay Description The inhibitory activities of compounds of the invention against p38MAPKγ (MAPK12: Invitrogen), were evaluated in a similar fashion to that descr... | J Med Chem 50: 984-1000 (2007) BindingDB Entry DOI: 10.7270/Q2PG1V1T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase HCK (Homo sapiens (Human)) | BDBM142598 (US10238658, Example Reference | US10813932, Refere...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a |
Bayer HealthCare Pharmaceuticals Corporation | Assay Description The inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), were evaluated in a similar fashion to that descr... | J Med Chem 50: 984-1000 (2007) BindingDB Entry DOI: 10.7270/Q2PG1V1T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human)) | BDBM142598 (US10238658, Example Reference | US10813932, Refere...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a |
Bayer HealthCare Pharmaceuticals Corporation | Assay Description The inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), were evaluated in a similar fashion to that descr... | J Med Chem 50: 984-1000 (2007) BindingDB Entry DOI: 10.7270/Q2PG1V1T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase SYK (Homo sapiens (Human)) | BDBM142598 (US10238658, Example Reference | US10813932, Refere...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | n/a | 9 | n/a | n/a | n/a | n/a | n/a |
Bayer HealthCare Pharmaceuticals Corporation | Assay Description The inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), were evaluated in a similar fashion to that descr... | J Med Chem 50: 984-1000 (2007) BindingDB Entry DOI: 10.7270/Q2PG1V1T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glycogen synthase kinase-3 (Homo sapiens (Human)) | BDBM142598 (US10238658, Example Reference | US10813932, Refere...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | n/a | 180 | n/a | n/a | n/a | n/a | n/a |
Bayer HealthCare Pharmaceuticals Corporation | Assay Description The inhibitory activities of test compounds against the GSK 3α enzyme isoform (Invitrogen), were evaluated by determining the level of activatio... | J Med Chem 50: 984-1000 (2007) BindingDB Entry DOI: 10.7270/Q2PG1V1T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glycogen synthase kinase-3 beta (Homo sapiens (Human)) | BDBM142598 (US10238658, Example Reference | US10813932, Refere...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | n/a | 24 | n/a | n/a | n/a | n/a | n/a |
Bayer HealthCare Pharmaceuticals Corporation | Assay Description The inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), were evaluated in a similar fashion to that descr... | J Med Chem 50: 984-1000 (2007) BindingDB Entry DOI: 10.7270/Q2PG1V1T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 14 (Homo sapiens (Human)) | BDBM142598 (US10238658, Example Reference | US10813932, Refere...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
Respivert Limited US Patent | Assay Description p38 MAPKα: The inhibitory activities of test compounds against the p38 MAPKα isoform (MAPK14: Invitrogen), were evaluated indirectly by det... | US Patent US10813932 (2020) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 12 Gamma (Homo sapiens (Human)) | BDBM142598 (US10238658, Example Reference | US10813932, Refere...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 344 | n/a | n/a | n/a | n/a | n/a | n/a |
Respivert Limited US Patent | Assay Description p38 MAPKγ: The inhibitory activities of compounds of the invention against p38MAPKγ (MAPK12: Invitrogen), were evaluated in a similar fashi... | US Patent US10813932 (2020) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glycogen synthase kinase-3 (Homo sapiens (Human)) | BDBM142598 (US10238658, Example Reference | US10813932, Refere...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 45 | n/a | n/a | n/a | n/a | n/a | n/a |
Respivert Limited US Patent | Assay Description GSK 3α: The inhibitory activities of test compounds against the GSK 3α enzyme isoform (Invitrogen), were evaluated by determining the level... | US Patent US10813932 (2020) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Calmodulin/Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human)) | BDBM142598 (US10238658, Example Reference | US10813932, Refere...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
Respivert Limited US Patent | Assay Description c-Src and Syk: The inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), were evaluated in a similar fashio... | US Patent US10813932 (2020) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase SYK (Homo sapiens (Human)) | BDBM142598 (US10238658, Example Reference | US10813932, Refere...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 42 | n/a | n/a | n/a | n/a | n/a | n/a |
Respivert Limited US Patent | Assay Description c-Src and Syk: The inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), were evaluated in a similar fashio... | US Patent US10813932 (2020) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 14 (Homo sapiens (Human)) | BDBM142598 (US10238658, Example Reference | US10813932, Refere...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a |
Respivert Limited US Patent | Assay Description p38 MAPKα: The inhibitory activities of test compounds against the p38 MAPKα isoform (MAPK14: Invitrogen), were evaluated indirectly by det... | US Patent US10813932 (2020) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 12 Gamma (Homo sapiens (Human)) | BDBM142598 (US10238658, Example Reference | US10813932, Refere...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a |
Respivert Limited US Patent | Assay Description p38 MAPKγ: The inhibitory activities of compounds of the invention against p38MAPKγ (MAPK12: Invitrogen), were evaluated in a similar fashi... | US Patent US10813932 (2020) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
hck (Homo sapiens (Human)) | BDBM142598 (US10238658, Example Reference | US10813932, Refere...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a |
Respivert Limited US Patent | US Patent US10813932 (2020) | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Calmodulin/Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human)) | BDBM142598 (US10238658, Example Reference | US10813932, Refere...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a |
Respivert Limited US Patent | Assay Description c-Src and Syk: The inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), were evaluated in a similar fashio... | US Patent US10813932 (2020) | |||||||||||
More data for this Ligand-Target Pair |
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