BDBM142608 US8933228, 24

SMILES: COc1ccc(cn1)-n1nc(cc1NC(=O)Nc1ccc(Oc2ccnc3[nH]c(=O)n(C)c23)c2ccccc12)C(C)(C)C

InChI Key: InChIKey=QAKIGHBHPHZCJC-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 142608   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM142608 (US8933228, 24) Show SMILES COc1ccc(cn1)-n1nc(cc1NC(=O)Nc1ccc(Oc2ccnc3[nH]c(=O)n(C)c23)c2ccccc12)C(C)(C)C Show InChI InChI=1S/C31H30N8O4/c1-31(2,3)24-16-25(39(37-24)18-10-13-26(42-5)33-17-18)35-29(40)34-21-11-12-22(20-9-7-6-8-19(20)21)43-23-14-15-32-28-27(23)38(4)30(41)36-28/h6-17H,1-5H3,(H,32,36,41)(H2,34,35,40)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
Respivert, Ltd. US Patent					Assay Description The enzyme inhibitory activity of test compounds was determined by fluorescence resonance energy transfer (FRET) using synthetic peptides labelled wi...				US Patent US8933228 (2015) BindingDB Entry DOI: 10.7270/Q2RV0MDW
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM142608 (US8933228, 24) Show SMILES COc1ccc(cn1)-n1nc(cc1NC(=O)Nc1ccc(Oc2ccnc3[nH]c(=O)n(C)c23)c2ccccc12)C(C)(C)C Show InChI InChI=1S/C31H30N8O4/c1-31(2,3)24-16-25(39(37-24)18-10-13-26(42-5)33-17-18)35-29(40)34-21-11-12-22(20-9-7-6-8-19(20)21)43-23-14-15-32-28-27(23)38(4)30(41)36-28/h6-17H,1-5H3,(H,32,36,41)(H2,34,35,40)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Respivert, Ltd. US Patent					Assay Description The enzyme inhibitory activity of test compounds was determined by fluorescence resonance energy transfer (FRET) using synthetic peptides labelled wi...				US Patent US8933228 (2015) BindingDB Entry DOI: 10.7270/Q2RV0MDW
					More data for this Ligand-Target Pair
Tyrosine-protein kinase HCK (Homo sapiens (Human))	BDBM142608 (US8933228, 24) Show SMILES COc1ccc(cn1)-n1nc(cc1NC(=O)Nc1ccc(Oc2ccnc3[nH]c(=O)n(C)c23)c2ccccc12)C(C)(C)C Show InChI InChI=1S/C31H30N8O4/c1-31(2,3)24-16-25(39(37-24)18-10-13-26(42-5)33-17-18)35-29(40)34-21-11-12-22(20-9-7-6-8-19(20)21)43-23-14-15-32-28-27(23)38(4)30(41)36-28/h6-17H,1-5H3,(H,32,36,41)(H2,34,35,40)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Respivert, Ltd. US Patent					Assay Description The enzyme inhibitory activity of test compounds was determined by fluorescence resonance energy transfer (FRET) using synthetic peptides labelled wi...				US Patent US8933228 (2015) BindingDB Entry DOI: 10.7270/Q2RV0MDW
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 12 (Homo sapiens (Human))	BDBM142608 (US8933228, 24) Show SMILES COc1ccc(cn1)-n1nc(cc1NC(=O)Nc1ccc(Oc2ccnc3[nH]c(=O)n(C)c23)c2ccccc12)C(C)(C)C Show InChI InChI=1S/C31H30N8O4/c1-31(2,3)24-16-25(39(37-24)18-10-13-26(42-5)33-17-18)35-29(40)34-21-11-12-22(20-9-7-6-8-19(20)21)43-23-14-15-32-28-27(23)38(4)30(41)36-28/h6-17H,1-5H3,(H,32,36,41)(H2,34,35,40)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	126	n/a	n/a	n/a	n/a	n/a	n/a
Respivert, Ltd. US Patent					Assay Description The enzyme inhibitory activity of test compounds was determined by fluorescence resonance energy transfer (FRET) using synthetic peptides labelled wi...				US Patent US8933228 (2015) BindingDB Entry DOI: 10.7270/Q2RV0MDW
					More data for this Ligand-Target Pair