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SMILES: CC1(C)Cc2[nH]c(cc2C(=O)N1)-c1ccnc(N)n1

InChI Key: InChIKey=VMRFHULWSHKVIH-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 27356   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Cell division cycle 7-related protein kinase [58-574]/Protein DBF4 homolog A


(Homo sapiens (Human))		BDBM27356
PNG
(2-(2-aminopyrimidin-4-yl)-6,6-dimethyl-1H,4H,5H,6H...)
Show SMILES CC1(C)Cc2[nH]c(cc2C(=O)N1)-c1ccnc(N)n1
Show InChI InChI=1S/C13H15N5O/c1-13(2)6-10-7(11(19)18-13)5-9(16-10)8-3-4-15-12(14)17-8/h3-5,16H,6H2,1-2H3,(H,18,19)(H2,14,15,17)
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Article
PubMed
n/an/a 64n/an/an/an/a7.925



Nerviano Medical Sciences Srl



Assay Description
The potency of the compound toward kinase activity was determined using a Dowex resin-based assay. The substrate was phosphorylated by kinase in the ...

J Med Chem 52: 293-307 (2009)


Article DOI: 10.1021/jm800977q
BindingDB Entry DOI: 10.7270/Q27W69JX
More data for this
Ligand-Target Pair