BDBM31881 DL-indole-3-lactic acid

SMILES: OC(Cc1c[nH]c2ccccc12)C(O)=O

InChI Key: InChIKey=XGILAAMKEQUXLS-UHFFFAOYSA-N

Data: 1 IC50

PDB links: 2 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 31881   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Kynurenine Aminotransferase 1/Glutamine Transaminase K (Homo sapiens (Human))	BDBM31881 (DL-indole-3-lactic acid) Show SMILES OC(Cc1c[nH]c2ccccc12)C(O)=O Show InChI InChI=1S/C11H11NO3/c13-10(11(14)15)5-7-6-12-9-4-2-1-3-8(7)9/h1-4,6,10,12-13H,5H2,(H,14,15)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	2.20E+5	n/a	n/a	n/a	n/a	7.5	38
Virginia Tech					Assay Description A typical reaction mixture contains kynurenine, alpha-ketobutyrate, PLP and hKAT-I in the presence of test compound. The reaction mixture was incubat...				J Med Chem 52: 2786-93 (2009) Article DOI: 10.1021/jm9000874 BindingDB Entry DOI: 10.7270/Q2GH9G8X
					More data for this Ligand-Target Pair