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BDBM339819 US9757364, Compound 13

SMILES: CCn1cc(cn1)-c1cnc2ccc(nc2c1)N(CCNC(C)C)c1cc(OC)cc(OC)c1

InChI Key:

Data: 5 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 339819   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Fibroblast growth factor receptor 1


(Homo sapiens (Human))
BDBM339819
PNG
(US9757364, Compound 13)
Show SMILES CCn1cc(cn1)-c1cnc2ccc(nc2c1)N(CCNC(C)C)c1cc(OC)cc(OC)c1
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1.29n/an/an/an/an/an/a



ASTEX THERAPEUTICS LTD

US Patent




US Patent US9757364 (2017)


BindingDB Entry DOI: 10.7270/Q2SB47VT
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 2


(Homo sapiens (Human))
BDBM339819
PNG
(US9757364, Compound 13)
Show SMILES CCn1cc(cn1)-c1cnc2ccc(nc2c1)N(CCNC(C)C)c1cc(OC)cc(OC)c1
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 3.24n/an/an/an/an/an/a



ASTEX THERAPEUTICS LTD

US Patent




US Patent US9757364 (2017)


BindingDB Entry DOI: 10.7270/Q2SB47VT
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (Human))
BDBM339819
PNG
(US9757364, Compound 13)
Show SMILES CCn1cc(cn1)-c1cnc2ccc(nc2c1)N(CCNC(C)C)c1cc(OC)cc(OC)c1
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 18.2n/an/an/an/an/an/a



ASTEX THERAPEUTICS LTD

US Patent




US Patent US9757364 (2017)


BindingDB Entry DOI: 10.7270/Q2SB47VT
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 4


(Homo sapiens (Human))
BDBM339819
PNG
(US9757364, Compound 13)
Show SMILES CCn1cc(cn1)-c1cnc2ccc(nc2c1)N(CCNC(C)C)c1cc(OC)cc(OC)c1
PDB

KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 6.31n/an/an/an/an/an/a



ASTEX THERAPEUTICS LTD

US Patent




US Patent US9757364 (2017)


BindingDB Entry DOI: 10.7270/Q2SB47VT
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 3


(Homo sapiens (Human))
BDBM339819
PNG
(US9757364, Compound 13)
Show SMILES CCn1cc(cn1)-c1cnc2ccc(nc2c1)N(CCNC(C)C)c1cc(OC)cc(OC)c1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 3.55n/an/an/an/an/an/a



ASTEX THERAPEUTICS LTD

US Patent




US Patent US9757364 (2017)


BindingDB Entry DOI: 10.7270/Q2SB47VT
More data for this
Ligand-Target Pair