BDBM37633 (2S)-2-amino-3-(4-hydroxy-3-iodo-phenyl)propionic acid::(2S)-2-amino-3-(4-hydroxy-3-iodophenyl)propanoic acid::(2S)-2-azanyl-3-(3-iodanyl-4-oxidanyl-phenyl)propanoic acid::3-IODO-L-TYROSINE::3-Iodo-L-tyrosine (I-Tyr)::MLS000069664::Monoiodotyrosine::SMR000059143::cid_439744

SMILES: N[C@@H](Cc1ccc(O)c(I)c1)C(O)=O

InChI Key: InChIKey=UQTZMGFTRHFAAM-ZETCQYMHSA-N

Data: 2 KI  4 IC50  2 Kd

PDB links: 31 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 37633   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
N-formyl peptide receptor 2 (Homo sapiens (Human))	BDBM37633 ((2S)-2-amino-3-(4-hydroxy-3-iodo-phenyl)propionic ...) Show SMILES N[C@@H](Cc1ccc(O)c(I)c1)C(O)=O Show InChI InChI=1S/C9H10INO3/c10-6-3-5(1-2-8(6)12)4-7(11)9(13)14/h1-3,7,12H,4,11H2,(H,13,14)/t7-/m0/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	Purchase DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	PCBioAssay	>4.03E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
NMMLSC Curated by PubChem BioAssay					Assay Description University of New Mexico Assay Overview Assay Support: NIH 1R03MH076381-01 Assay for Formylpeptide Receptor Family Ligands PI: Bruce S. Edwards, Ph....				PubChem Bioassay (2007) BindingDB Entry DOI: 10.7270/Q2DF6PMF
					More data for this Ligand-Target Pair
fMet-Leu-Phe receptor (Homo sapiens (Human))	BDBM37633 ((2S)-2-amino-3-(4-hydroxy-3-iodo-phenyl)propionic ...) Show SMILES N[C@@H](Cc1ccc(O)c(I)c1)C(O)=O Show InChI InChI=1S/C9H10INO3/c10-6-3-5(1-2-8(6)12)4-7(11)9(13)14/h1-3,7,12H,4,11H2,(H,13,14)/t7-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	PCBioAssay	>4.37E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
NMMLSC Curated by PubChem BioAssay					Assay Description University of New Mexico Assay Overview: Assay Support: NIH 1R03MH076381-01 Assay for Formylpeptide Receptor Family Ligands PI: Bruce S. Edwards, Ph...				PubChem Bioassay (2007) BindingDB Entry DOI: 10.7270/Q2NZ862K
					More data for this Ligand-Target Pair
Iodotyrosine deiodinase (IYD) (Homo sapiens (Human))	BDBM37633 ((2S)-2-amino-3-(4-hydroxy-3-iodo-phenyl)propionic ...) Show SMILES N[C@@H](Cc1ccc(O)c(I)c1)C(O)=O Show InChI InChI=1S/C9H10INO3/c10-6-3-5(1-2-8(6)12)4-7(11)9(13)14/h1-3,7,12H,4,11H2,(H,13,14)/t7-/m0/s1	PDB GoogleScholar AffyNet	Purchase DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a
Johns Hopkins University					Assay Description Dissociation constants (Kd) for the ligands of IYD were determined by their ability to quench the fluorescence of the oxidized FMN (FMNox) (λex ...				Biochemistry 56: 1130-1139 (2017) Article DOI: 10.1021/acs.biochem.6b01308 BindingDB Entry DOI: 10.7270/Q2ZK5FJM
					More data for this Ligand-Target Pair				3D Structure (crystal)
Iodotyrosine deiodinase (IYD) (Haliscomenobacter hydrossis)	BDBM37633 ((2S)-2-amino-3-(4-hydroxy-3-iodo-phenyl)propionic ...) Show SMILES N[C@@H](Cc1ccc(O)c(I)c1)C(O)=O Show InChI InChI=1S/C9H10INO3/c10-6-3-5(1-2-8(6)12)4-7(11)9(13)14/h1-3,7,12H,4,11H2,(H,13,14)/t7-/m0/s1	PDB GoogleScholar AffyNet	Purchase DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	n/a	8.20E+3	n/a	n/a	n/a	n/a	n/a
Johns Hopkins University					Assay Description Dissociation constants (Kd) for the ligands of IYD were determined by their ability to quench the fluorescence of the oxidized FMN (FMNox) (λex ...				Biochemistry 56: 1130-1139 (2017) Article DOI: 10.1021/acs.biochem.6b01308 BindingDB Entry DOI: 10.7270/Q2ZK5FJM
					More data for this Ligand-Target Pair				3D Structure (crystal)
Tyrosine 3-hydroxylase (Rattus norvegicus)	BDBM37633 ((2S)-2-amino-3-(4-hydroxy-3-iodo-phenyl)propionic ...) Show SMILES N[C@@H](Cc1ccc(O)c(I)c1)C(O)=O Show InChI InChI=1S/C9H10INO3/c10-6-3-5(1-2-8(6)12)4-7(11)9(13)14/h1-3,7,12H,4,11H2,(H,13,14)/t7-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of rat tyrosine hydroxylase				Bioorg Med Chem 18: 7675-99 (2010) Article DOI: 10.1016/j.bmc.2010.07.034 BindingDB Entry DOI: 10.7270/Q2DF6S69
					More data for this Ligand-Target Pair
N-formyl peptide receptor 2 (Homo sapiens (Human))	BDBM37633 ((2S)-2-amino-3-(4-hydroxy-3-iodo-phenyl)propionic ...) Show SMILES N[C@@H](Cc1ccc(O)c(I)c1)C(O)=O Show InChI InChI=1S/C9H10INO3/c10-6-3-5(1-2-8(6)12)4-7(11)9(13)14/h1-3,7,12H,4,11H2,(H,13,14)/t7-/m0/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	Purchase DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	PCBioAssay	n/a	n/a	>6.67E+4	n/a	n/a	n/a	n/a	n/a	n/a
NMMLSC Curated by PubChem BioAssay					Assay Description University of New Mexico Assay Overview Assay Support: NIH 1R03MH076381-01 Assay for Formylpeptide Receptor Family Ligands PI: Bruce S. Edwards, Ph....				PubChem Bioassay (2007) BindingDB Entry DOI: 10.7270/Q2DF6PMF
					More data for this Ligand-Target Pair
fMet-Leu-Phe receptor (Homo sapiens (Human))	BDBM37633 ((2S)-2-amino-3-(4-hydroxy-3-iodo-phenyl)propionic ...) Show SMILES N[C@@H](Cc1ccc(O)c(I)c1)C(O)=O Show InChI InChI=1S/C9H10INO3/c10-6-3-5(1-2-8(6)12)4-7(11)9(13)14/h1-3,7,12H,4,11H2,(H,13,14)/t7-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	PCBioAssay	n/a	n/a	>6.67E+4	n/a	n/a	n/a	n/a	n/a	n/a
NMMLSC Curated by PubChem BioAssay					Assay Description University of New Mexico Assay Overview: Assay Support: NIH 1R03MH076381-01 Assay for Formylpeptide Receptor Family Ligands PI: Bruce S. Edwards, Ph...				PubChem Bioassay (2007) BindingDB Entry DOI: 10.7270/Q2J67FB5
					More data for this Ligand-Target Pair
Genome polyprotein (West Nile virus)	BDBM37633 ((2S)-2-amino-3-(4-hydroxy-3-iodo-phenyl)propionic ...) Show SMILES N[C@@H](Cc1ccc(O)c(I)c1)C(O)=O Show InChI InChI=1S/C9H10INO3/c10-6-3-5(1-2-8(6)12)4-7(11)9(13)14/h1-3,7,12H,4,11H2,(H,13,14)/t7-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	PCBioAssay	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Pittsburgh Molecular Library Screening Center Curated by PubChem BioAssay					Assay Description The HTS assay to identify Inhibitors of West Nile Virus (WNV) NS2bNS3 Proteinase was proposed by Dr Alex Strongin of the Burnham Institute XO1-MH0776...				PubChem Bioassay (2007) BindingDB Entry DOI: 10.7270/Q2222S6W
					More data for this Ligand-Target Pair