BDBM384764 US10285983, Compound 188
SMILES: O=C(Nc1cncc(c1)-c1cnc2[nH]nc(-c3cc4c(ccnc4[nH]3)N3CCCCC3)c2c1)C1CC1
InChI Key: InChIKey=TUXINENVKGEBIJ-UHFFFAOYSA-N
Data: 1 EC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Proto-oncogene Wnt-1 (Homo sapiens (human)) | BDBM384764 (US10285983, Compound 188) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 3.31E+3 | n/a | n/a | n/a | n/a |
Istanbul University | Assay Description SW480 colon carcinoma cells were transduced with a lentiviral vector expressing luciferase with a human Sp5 promoter consisting of a sequence of eigh... | Bioorg Med Chem 16: 9113-20 (2008) BindingDB Entry DOI: 10.7270/Q2D79DQJ | |||||||||||
More data for this Ligand-Target Pair |