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Found 1 hit Enz. Inhib. hit(s) with Target = 'Proto-oncogene Wnt-1' and Ligand = 'BDBM384764'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Proto-oncogene Wnt-1


(Homo sapiens (human))		BDBM384764
PNG
(US10285983, Compound 188)
Show SMILES O=C(Nc1cncc(c1)-c1cnc2[nH]nc(-c3cc4c(ccnc4[nH]3)N3CCCCC3)c2c1)C1CC1
Show InChI InChI=1S/C27H26N8O/c36-27(16-4-5-16)31-19-10-17(13-28-15-19)18-11-21-24(33-34-26(21)30-14-18)22-12-20-23(6-7-29-25(20)32-22)35-8-2-1-3-9-35/h6-7,10-16H,1-5,8-9H2,(H,29,32)(H,31,36)(H,30,33,34)
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 3.31E+3n/an/an/an/a



Istanbul University



Assay Description
SW480 colon carcinoma cells were transduced with a lentiviral vector expressing luciferase with a human Sp5 promoter consisting of a sequence of eigh...

Bioorg Med Chem 16: 9113-20 (2008)


BindingDB Entry DOI: 10.7270/Q2D79DQJ
More data for this
Ligand-Target Pair