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BDBM4713 3-[(Aminoiminomethyl)amino]-4-[(methylamino)carbonyl]benzoic Acid::3-carbamimidamido-4-(methylcarbamoyl)benzoic acid::Benzoic Acid deriv. 160

SMILES: [#6]-[#7]-[#6](=O)-c1ccc(cc1\[#7]=[#6](/[#7])-[#7])-[#6](-[#8])=O

InChI Key: InChIKey=BXEJVSHCAXSLIH-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 4713   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Neuraminidase A


(Influenza A virus (N9))		BDBM4713
PNG
(3-[(Aminoiminomethyl)amino]-4-[(methylamino)carbon...)
Show SMILES [#6]-[#7]-[#6](=O)-c1ccc(cc1\[#7]=[#6](/[#7])-[#7])-[#6](-[#8])=O
Show InChI InChI=1S/C10H12N4O3/c1-13-8(15)6-3-2-5(9(16)17)4-7(6)14-10(11)12/h2-4H,1H3,(H,13,15)(H,16,17)(H4,11,12,14)
PDB
MMDB

UniProtKB/SwissProt

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PC cid
PC sid
UniChem

Patents
Article
PubMed
n/an/a 5.00E+3n/an/an/an/a6.537



BioCryst Pharmaceuticals, Inc.



Assay Description
A standard fluorimetric assay was used to measure influenza virus neuraminidase activity. The substrate 2 -(4-methylumbelliferyl)-alpha-D-acetylneura...

J Med Chem 40: 4030-52 (1997)


Article DOI: 10.1021/jm970479e
BindingDB Entry DOI: 10.7270/Q2X63K41
More data for this
Ligand-Target Pair