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BDBM47713 MLS000113446::N-(1,5-dimethyl-3-oxidanylidene-2-phenyl-pyrazol-4-yl)-3,4-dimethoxy-N-methyl-benzenesulfonamide::N-(1,5-dimethyl-3-oxo-2-phenyl-4-pyrazolyl)-3,4-dimethoxy-N-methylbenzenesulfonamide::N-(1,5-dimethyl-3-oxo-2-phenylpyrazol-4-yl)-3,4-dimethoxy-N-methylbenzenesulfonamide::N-(3-keto-1,5-dimethyl-2-phenyl-3-pyrazolin-4-yl)-3,4-dimethoxy-N-methyl-benzenesulfonamide::SMR000109344::cid_1075678

SMILES: COc1ccc(cc1OC)S(=O)(=O)N(C)c1c(C)n(C)n(-c2ccccc2)c1=O

InChI Key: InChIKey=PQELSGOHJDRCFD-UHFFFAOYSA-N

Data: 5 EC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 47713   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
RGS7


(Homo sapiens (Human))
BDBM47713
PNG
(MLS000113446 | N-(1,5-dimethyl-3-oxidanylidene-2-p...)
Show SMILES COc1ccc(cc1OC)S(=O)(=O)N(C)c1c(C)n(C)n(-c2ccccc2)c1=O
Show InChI InChI=1S/C20H23N3O5S/c1-14-19(20(24)23(21(14)2)15-9-7-6-8-10-15)22(3)29(25,26)16-11-12-17(27-4)18(13-16)28-5/h6-13H,1-5H3
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
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PC cid
PC sid
UniChem
PCBioAssay
n/an/an/an/a>3.00E+4n/an/an/an/a



NMMLSC

Curated by PubChem BioAssay


Assay Description
University of New Mexico Assay Overview: Assay Support: NIH R21NS057014 HTS to identify small molecule regulators of RGS family protein interaction...


PubChem Bioassay (2009)


BindingDB Entry DOI: 10.7270/Q2PV6HS7
More data for this
Ligand-Target Pair
G protein signalling regulator 19


(Homo sapiens (Human))
BDBM47713
PNG
(MLS000113446 | N-(1,5-dimethyl-3-oxidanylidene-2-p...)
Show SMILES COc1ccc(cc1OC)S(=O)(=O)N(C)c1c(C)n(C)n(-c2ccccc2)c1=O
Show InChI InChI=1S/C20H23N3O5S/c1-14-19(20(24)23(21(14)2)15-9-7-6-8-10-15)22(3)29(25,26)16-11-12-17(27-4)18(13-16)28-5/h6-13H,1-5H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

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antibodypedia
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PC cid
PC sid
UniChem
PCBioAssay
n/an/an/an/a>3.00E+4n/an/an/an/a



NMMLSC

Curated by PubChem BioAssay


Assay Description
University of New Mexico Assay Overview: Assay Support: NIH R21NS057014 HTS to identify small molecule regulators of RGS family protein interaction...


PubChem Bioassay (2009)


BindingDB Entry DOI: 10.7270/Q2K35S27
More data for this
Ligand-Target Pair
regulator of G-protein signaling 4


(Homo sapiens (Human))
BDBM47713
PNG
(MLS000113446 | N-(1,5-dimethyl-3-oxidanylidene-2-p...)
Show SMILES COc1ccc(cc1OC)S(=O)(=O)N(C)c1c(C)n(C)n(-c2ccccc2)c1=O
Show InChI InChI=1S/C20H23N3O5S/c1-14-19(20(24)23(21(14)2)15-9-7-6-8-10-15)22(3)29(25,26)16-11-12-17(27-4)18(13-16)28-5/h6-13H,1-5H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
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PC cid
PC sid
UniChem
Article
PCBioAssay
n/an/an/an/a 3.00E+4n/an/an/an/a



NMMLSC

Curated by PubChem BioAssay


Assay Description
University of New Mexico Assay Overview: Assay Support: NIH R21NS057014 HTS to identify small molecule regulators of RGS family protein interaction...


PubChem Bioassay (2009)


Article DOI: 10.1021/cb400177q
BindingDB Entry DOI: 10.7270/Q2F76B0G
More data for this
Ligand-Target Pair
Regulator of G-protein signaling 8


(Homo sapiens (Human))
BDBM47713
PNG
(MLS000113446 | N-(1,5-dimethyl-3-oxidanylidene-2-p...)
Show SMILES COc1ccc(cc1OC)S(=O)(=O)N(C)c1c(C)n(C)n(-c2ccccc2)c1=O
Show InChI InChI=1S/C20H23N3O5S/c1-14-19(20(24)23(21(14)2)15-9-7-6-8-10-15)22(3)29(25,26)16-11-12-17(27-4)18(13-16)28-5/h6-13H,1-5H3
PDB
MMDB

Reactome pathway
KEGG

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PC cid
PC sid
UniChem
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n/an/an/an/a>3.00E+4n/an/an/an/a



NMMLSC

Curated by PubChem BioAssay


Assay Description
University of New Mexico Assay Overview: Assay Support: NIH R21NS057014 HTS to identify small molecule regulators of RGS family protein interaction...


PubChem Bioassay (2009)


BindingDB Entry DOI: 10.7270/Q2TM78JD
More data for this
Ligand-Target Pair
regulator of G-protein signalling 16


(Homo sapiens (Human))
BDBM47713
PNG
(MLS000113446 | N-(1,5-dimethyl-3-oxidanylidene-2-p...)
Show SMILES COc1ccc(cc1OC)S(=O)(=O)N(C)c1c(C)n(C)n(-c2ccccc2)c1=O
Show InChI InChI=1S/C20H23N3O5S/c1-14-19(20(24)23(21(14)2)15-9-7-6-8-10-15)22(3)29(25,26)16-11-12-17(27-4)18(13-16)28-5/h6-13H,1-5H3
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem
PCBioAssay
n/an/an/an/a>3.00E+4n/an/an/an/a



NMMLSC

Curated by PubChem BioAssay


Assay Description
University of New Mexico Assay Overview: Assay Support: NIH R21NS057014 HTS to identify small molecule regulators of RGS family protein interaction...


PubChem Bioassay (2009)


BindingDB Entry DOI: 10.7270/Q2FB51BW
More data for this
Ligand-Target Pair