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BDBM50009057 (R)Methyl-(1-methyl-2-phenyl-ethyl)-amine::METHAMPHETAMINE::METHAMPHETAMINE (+)::METHAMPHETAMINE (-)::Methyl-(1-methyl-2-phenyl-ethyl)-amine::Methyl-(1-methyl-2-phenyl-ethyl)-amine(methamphetamine)

SMILES: CNC(C)Cc1ccccc1

InChI Key: InChIKey=MYWUZJCMWCOHBA-UHFFFAOYSA-N

Data: 18 KI

PDB links: 3 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 18 hits for monomerid = 50009057   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Sodium-dependent noradrenaline transporter


(Homo sapiens (human))
BDBM50009057
PNG
((R)Methyl-(1-methyl-2-phenyl-ethyl)-amine | METHAM...)
Show SMILES CNC(C)Cc1ccccc1
Show InChI InChI=1S/C10H15N/c1-9(11-2)8-10-6-4-3-5-7-10/h3-7,9,11H,8H2,1-2H3
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PubMed
12.3n/an/an/an/an/an/an/an/a



National Institute on Drug Abuse

Curated by PDSP Ki Database




J Pharmacol Exp Ther 307: 138-45 (2003)

More data for this
Ligand-Target Pair
Sodium-dependent dopamine transporter


(Homo sapiens (human))
BDBM50009057
PNG
((R)Methyl-(1-methyl-2-phenyl-ethyl)-amine | METHAM...)
Show SMILES CNC(C)Cc1ccccc1
Show InChI InChI=1S/C10H15N/c1-9(11-2)8-10-6-4-3-5-7-10/h3-7,9,11H,8H2,1-2H3
NCI pathway
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PubMed
24.5n/an/an/an/an/an/an/an/a



National Institute on Drug Abuse

Curated by PDSP Ki Database




J Pharmacol Exp Ther 307: 138-45 (2003)

More data for this
Ligand-Target Pair
Norepinephrine transporter


(RAT)
BDBM50009057
PNG
((R)Methyl-(1-methyl-2-phenyl-ethyl)-amine | METHAM...)
Show SMILES CNC(C)Cc1ccccc1
Show InChI InChI=1S/C10H15N/c1-9(11-2)8-10-6-4-3-5-7-10/h3-7,9,11H,8H2,1-2H3
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PubMed
48n/an/an/an/an/an/an/an/a



NIH

Curated by PDSP Ki Database




Synapse 39: 32-41 (2001)

More data for this
Ligand-Target Pair
Dopamine Transporter (DAT)


(Rattus norvegicus (rat))
BDBM50009057
PNG
((R)Methyl-(1-methyl-2-phenyl-ethyl)-amine | METHAM...)
Show SMILES CNC(C)Cc1ccccc1
Show InChI InChI=1S/C10H15N/c1-9(11-2)8-10-6-4-3-5-7-10/h3-7,9,11H,8H2,1-2H3
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PubMed
114n/an/an/an/an/an/an/an/a



NIH

Curated by PDSP Ki Database




Synapse 39: 32-41 (2001)

More data for this
Ligand-Target Pair
Norepinephrine transporter


(RAT)
BDBM50009057
PNG
((R)Methyl-(1-methyl-2-phenyl-ethyl)-amine | METHAM...)
Show SMILES CNC(C)Cc1ccccc1
Show InChI InChI=1S/C10H15N/c1-9(11-2)8-10-6-4-3-5-7-10/h3-7,9,11H,8H2,1-2H3
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PubMed
234n/an/an/an/an/an/an/an/a



NIH

Curated by PDSP Ki Database




Synapse 39: 32-41 (2001)

More data for this
Ligand-Target Pair
Dopamine Transporter (DAT)


(Rattus norvegicus (rat))
BDBM50009057
PNG
((R)Methyl-(1-methyl-2-phenyl-ethyl)-amine | METHAM...)
Show SMILES CNC(C)Cc1ccccc1
Show InChI InChI=1S/C10H15N/c1-9(11-2)8-10-6-4-3-5-7-10/h3-7,9,11H,8H2,1-2H3
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353n/an/an/an/an/an/an/an/a



Novo Industri A/S

Curated by PDSP Ki Database




Citation and Details
More data for this
Ligand-Target Pair
Alpha-1A adrenergic receptor


(Rattus norvegicus (Rat))
BDBM50009057
PNG
((R)Methyl-(1-methyl-2-phenyl-ethyl)-amine | METHAM...)
Show SMILES CNC(C)Cc1ccccc1
Show InChI InChI=1S/C10H15N/c1-9(11-2)8-10-6-4-3-5-7-10/h3-7,9,11H,8H2,1-2H3
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600n/an/an/an/an/an/an/an/a



TBA

Curated by PDSP Ki Database




Citation and Details
More data for this
Ligand-Target Pair
Serotonin and norepinephrine transporters (SERT/NET)


(Homo sapiens (human))
BDBM50009057
PNG
((R)Methyl-(1-methyl-2-phenyl-ethyl)-amine | METHAM...)
Show SMILES CNC(C)Cc1ccccc1
Show InChI InChI=1S/C10H15N/c1-9(11-2)8-10-6-4-3-5-7-10/h3-7,9,11H,8H2,1-2H3
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PubMed
736n/an/an/an/an/an/an/an/a



National Institute on Drug Abuse

Curated by PDSP Ki Database




J Pharmacol Exp Ther 307: 138-45 (2003)

More data for this
Ligand-Target Pair
Sodium-dependent serotonin transporter


(Rattus norvegicus (rat))
BDBM50009057
PNG
((R)Methyl-(1-methyl-2-phenyl-ethyl)-amine | METHAM...)
Show SMILES CNC(C)Cc1ccccc1
Show InChI InChI=1S/C10H15N/c1-9(11-2)8-10-6-4-3-5-7-10/h3-7,9,11H,8H2,1-2H3
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PubMed
2.14E+3n/an/an/an/an/an/an/an/a



NIH

Curated by PDSP Ki Database




Synapse 39: 32-41 (2001)

More data for this
Ligand-Target Pair
Dopamine Transporter (DAT)


(Rattus norvegicus (rat))
BDBM50009057
PNG
((R)Methyl-(1-methyl-2-phenyl-ethyl)-amine | METHAM...)
Show SMILES CNC(C)Cc1ccccc1
Show InChI InChI=1S/C10H15N/c1-9(11-2)8-10-6-4-3-5-7-10/h3-7,9,11H,8H2,1-2H3
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PubMed
4.84E+3n/an/an/an/an/an/an/an/a



NIH

Curated by PDSP Ki Database




Synapse 39: 32-41 (2001)

More data for this
Ligand-Target Pair
Alpha-1A adrenergic receptor


(Rattus norvegicus (Rat))
BDBM50009057
PNG
((R)Methyl-(1-methyl-2-phenyl-ethyl)-amine | METHAM...)
Show SMILES CNC(C)Cc1ccccc1
Show InChI InChI=1S/C10H15N/c1-9(11-2)8-10-6-4-3-5-7-10/h3-7,9,11H,8H2,1-2H3
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PubMed
6.70E+3n/an/an/an/an/an/an/an/a



TBA

Curated by PDSP Ki Database




Citation and Details
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 1A (5-HT1A)


(Homo sapiens (human))
BDBM50009057
PNG
((R)Methyl-(1-methyl-2-phenyl-ethyl)-amine | METHAM...)
Show SMILES CNC(C)Cc1ccccc1
Show InChI InChI=1S/C10H15N/c1-9(11-2)8-10-6-4-3-5-7-10/h3-7,9,11H,8H2,1-2H3
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>1.00E+4n/an/an/an/an/an/an/an/a



SRI International

Curated by PDSP Ki Database




Citation and Details
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50009057
PNG
((R)Methyl-(1-methyl-2-phenyl-ethyl)-amine | METHAM...)
Show SMILES CNC(C)Cc1ccccc1
Show InChI InChI=1S/C10H15N/c1-9(11-2)8-10-6-4-3-5-7-10/h3-7,9,11H,8H2,1-2H3
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>1.00E+4n/an/an/an/an/an/an/an/a



SRI International

Curated by PDSP Ki Database




Citation and Details
More data for this
Ligand-Target Pair
Dopamine receptor D2L/neurotensin receptor NTS1


(Homo sapiens (Human))
BDBM50009057
PNG
((R)Methyl-(1-methyl-2-phenyl-ethyl)-amine | METHAM...)
Show SMILES CNC(C)Cc1ccccc1
Show InChI InChI=1S/C10H15N/c1-9(11-2)8-10-6-4-3-5-7-10/h3-7,9,11H,8H2,1-2H3
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>1.00E+4n/an/an/an/an/an/an/an/a



SRI International

Curated by PDSP Ki Database




Citation and Details
More data for this
Ligand-Target Pair
Serotonin receptor 2a and 2c (5HT2A and 5HT2C)


(Rattus norvegicus (Rat))
BDBM50009057
PNG
((R)Methyl-(1-methyl-2-phenyl-ethyl)-amine | METHAM...)
Show SMILES CNC(C)Cc1ccccc1
Show InChI InChI=1S/C10H15N/c1-9(11-2)8-10-6-4-3-5-7-10/h3-7,9,11H,8H2,1-2H3
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>1.00E+4n/an/an/an/an/an/an/an/a



SRI International

Curated by PDSP Ki Database




Citation and Details
More data for this
Ligand-Target Pair
HTR3A


(Mus musculus (house mouse))
BDBM50009057
PNG
((R)Methyl-(1-methyl-2-phenyl-ethyl)-amine | METHAM...)
Show SMILES CNC(C)Cc1ccccc1
Show InChI InChI=1S/C10H15N/c1-9(11-2)8-10-6-4-3-5-7-10/h3-7,9,11H,8H2,1-2H3
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>1.00E+4n/an/an/an/an/an/an/an/a



SRI International

Curated by PDSP Ki Database




Citation and Details
More data for this
Ligand-Target Pair
Dopamine D1 and D2 receptor


(Homo sapiens (Human))
BDBM50009057
PNG
((R)Methyl-(1-methyl-2-phenyl-ethyl)-amine | METHAM...)
Show SMILES CNC(C)Cc1ccccc1
Show InChI InChI=1S/C10H15N/c1-9(11-2)8-10-6-4-3-5-7-10/h3-7,9,11H,8H2,1-2H3
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>1.00E+4n/an/an/an/an/an/an/an/a



SRI International

Curated by PDSP Ki Database




Citation and Details
More data for this
Ligand-Target Pair
Sodium-dependent serotonin transporter


(Rattus norvegicus (rat))
BDBM50009057
PNG
((R)Methyl-(1-methyl-2-phenyl-ethyl)-amine | METHAM...)
Show SMILES CNC(C)Cc1ccccc1
Show InChI InChI=1S/C10H15N/c1-9(11-2)8-10-6-4-3-5-7-10/h3-7,9,11H,8H2,1-2H3
PDB

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PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



NIH

Curated by PDSP Ki Database




Synapse 39: 32-41 (2001)

More data for this
Ligand-Target Pair