BindingDB PrimarySearch

BDBM50010618 (+)-3-(1-Propyl-piperidin-3-yl)-phenol::3-((R)-1-Propyl-piperidin-3-yl)-phenol::3-(1-Propyl-piperidin-3-yl)-phenol::3PPP,(-)::CHEMBL7393::cid_202478

SMILES: CCCN1CCC[C@@H](C1)c1cccc(O)c1

InChI Key: InChIKey=HTSNFXAICLXZMA-ZDUSSCGKSA-N

Data: 8 KI 9 IC50 2 EC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 19 hits for monomerid = 50010618
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50010618 ((+)-3-(1-Propyl-piperidin-3-yl)-phenol \| 3-((R)-1-...) Show SMILES CCCN1CCC[C@@H](C1)c1cccc(O)c1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Innsbruck Curated by ChEMBL					Assay Description Affinity for sigma receptor type 1 of guinea pig using [3H]ifenprodil or (+)-[3H]pentazocine radioligand				J Med Chem 48: 4754-64 (2005) Article DOI: 10.1021/jm049073+ BindingDB Entry DOI: 10.7270/Q2639QHB
University of Innsbruck Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50010618 ((+)-3-(1-Propyl-piperidin-3-yl)-phenol \| 3-((R)-1-...) Show SMILES CCCN1CCC[C@@H](C1)c1cccc(O)c1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	155	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by PDSP K_i Database									Proc Natl Acad Sci U S A 81: 4983-7 (1984) Article DOI: 10.1073/pnas.81.15.4983 BindingDB Entry DOI: 10.7270/Q2JM284N
TBA Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50010618 ((+)-3-(1-Propyl-piperidin-3-yl)-phenol \| 3-((R)-1-...) Show SMILES CCCN1CCC[C@@H](C1)c1cccc(O)c1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	162	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by PDSP K_i Database									Proc Natl Acad Sci U S A 81: 4983-7 (1984) Article DOI: 10.1073/pnas.81.15.4983 BindingDB Entry DOI: 10.7270/Q2JM284N
TBA Curated by PDSP K_i Database					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50010618 ((+)-3-(1-Propyl-piperidin-3-yl)-phenol \| 3-((R)-1-...) Show SMILES CCCN1CCC[C@@H](C1)c1cccc(O)c1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	189	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro affinity against Dopamine receptor D2 using [3H]DP-5,6-ADTN radioligand in rat striatal homogenate				J Med Chem 29: 1889-95 (1986) BindingDB Entry DOI: 10.7270/Q2ZC83F6
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Cavia porcellus (Guinea pig))	BDBM50010618 ((+)-3-(1-Propyl-piperidin-3-yl)-phenol \| 3-((R)-1-...) Show SMILES CCCN1CCC[C@@H](C1)c1cccc(O)c1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	235	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by PDSP K_i Database									J Pharm Pharmacol 38: 374-9 (1986) Article DOI: 10.1111/j.2042-7158.1986.tb04590.x BindingDB Entry DOI: 10.7270/Q2JS9NXW
TBA Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Cavia porcellus (Guinea pig))	BDBM50010618 ((+)-3-(1-Propyl-piperidin-3-yl)-phenol \| 3-((R)-1-...) Show SMILES CCCN1CCC[C@@H](C1)c1cccc(O)c1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	280	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by PDSP K_i Database									J Pharm Pharmacol 38: 374-9 (1986) Article DOI: 10.1111/j.2042-7158.1986.tb04590.x BindingDB Entry DOI: 10.7270/Q2JS9NXW
TBA Curated by PDSP K_i Database					More data for this Ligand-Target Pair
C-8 sterol isomerase (Saccharomyces cerevisiae)	BDBM50010618 ((+)-3-(1-Propyl-piperidin-3-yl)-phenol \| 3-((R)-1-...) Show SMILES CCCN1CCC[C@@H](C1)c1cccc(O)c1 Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Innsbruck Curated by ChEMBL					Assay Description Affinity for ERG2 of Sacchromyces cerevisiae using [3H]ifenprodil or (+)-[3H]pentazocine radioligand				J Med Chem 48: 4754-64 (2005) Article DOI: 10.1021/jm049073+ BindingDB Entry DOI: 10.7270/Q2639QHB
University of Innsbruck Curated by ChEMBL					More data for this Ligand-Target Pair
Anti-estrogen binding site (AEBS) (Homo sapiens (Human))	BDBM50010618 ((+)-3-(1-Propyl-piperidin-3-yl)-phenol \| 3-((R)-1-...) Show SMILES CCCN1CCC[C@@H](C1)c1cccc(O)c1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Innsbruck Curated by ChEMBL					Assay Description Affinity for human EMP expressed in ERG2 deficient strain of Sacchromyces cerevisiae using [3H]ifenprodil or (+)-[3H]pentazocine as radioligand				J Med Chem 48: 4754-64 (2005) Article DOI: 10.1021/jm049073+ BindingDB Entry DOI: 10.7270/Q2639QHB
University of Innsbruck Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50010618 ((+)-3-(1-Propyl-piperidin-3-yl)-phenol \| 3-((R)-1-...) Show SMILES CCCN1CCC[C@@H](C1)c1cccc(O)c1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.71E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of G£teborg Curated by ChEMBL					Assay Description Binding affinity against Dopamine receptor D2 using [3H]spiperone as radioligand				J Med Chem 30: 2169-74 (1988) BindingDB Entry DOI: 10.7270/Q2MW2HQJ
University of G£teborg Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50010618 ((+)-3-(1-Propyl-piperidin-3-yl)-phenol \| 3-((R)-1-...) Show SMILES CCCN1CCC[C@@H](C1)c1cccc(O)c1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	98	n/a	n/a	n/a	n/a	n/a	n/a
University of Lund Curated by ChEMBL					Assay Description In vitro inhibition of [3H]-N-0437 binding to Dopamine receptor D2 in rat striatal membranes				J Med Chem 33: 1015-22 (1990) BindingDB Entry DOI: 10.7270/Q2PV6JBT
University of Lund Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50010618 ((+)-3-(1-Propyl-piperidin-3-yl)-phenol \| 3-((R)-1-...) Show SMILES CCCN1CCC[C@@H](C1)c1cccc(O)c1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago 60607-7061 Curated by ChEMBL					Assay Description Inhibition of [3H]NANM binding to sigma receptor obtained from tissue homogenate preparation of fresh whole rat brain minus cerebellum				J Med Chem 41: 468-77 (1998) Article DOI: 10.1021/jm970059p BindingDB Entry DOI: 10.7270/Q27W6CW7
					More data for this Ligand-Target Pair
Prolylcarboxypeptidase (PRCP) (Homo sapiens (Human))	BDBM50010618 ((+)-3-(1-Propyl-piperidin-3-yl)-phenol \| 3-((R)-1-...) Show SMILES CCCN1CCC[C@@H](C1)c1cccc(O)c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago 60607-7061 Curated by ChEMBL					Assay Description Inhibition of binding to PCP receptor obtained from tissue homogenate preparation of fresh whole rat brain minus cerebellum				J Med Chem 41: 468-77 (1998) Article DOI: 10.1021/jm970059p BindingDB Entry DOI: 10.7270/Q27W6CW7
					More data for this Ligand-Target Pair
Dopamine receptor (Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...)	BDBM50010618 ((+)-3-(1-Propyl-piperidin-3-yl)-phenol \| 3-((R)-1-...) Show SMILES CCCN1CCC[C@@H](C1)c1cccc(O)c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	930	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description In vitro inhibition of [3H]haloperidol (HPD) binding to dopamine (DA) receptor of rat striatal membranes				J Med Chem 31: 1621-5 (1988) BindingDB Entry DOI: 10.7270/Q21G0PG9
Warner-Lambert Company Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50010618 ((+)-3-(1-Propyl-piperidin-3-yl)-phenol \| 3-((R)-1-...) Show SMILES CCCN1CCC[C@@H](C1)c1cccc(O)c1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
University of G£teborg Curated by ChEMBL					Assay Description In vitro for binding affinity against sigma receptor using [3H](+)-3-PPP as radioligand				J Med Chem 30: 2169-74 (1988) BindingDB Entry DOI: 10.7270/Q2MW2HQJ
University of G£teborg Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50010618 ((+)-3-(1-Propyl-piperidin-3-yl)-phenol \| 3-((R)-1-...) Show SMILES CCCN1CCC[C@@H](C1)c1cccc(O)c1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Oxford Curated by ChEMBL					Assay Description Displacement of spiperone from dopamine receptor D2 of rat brain membrane				J Med Chem 37: 1727-32 (1994) Checked by Author BindingDB Entry DOI: 10.7270/Q25B0408
University of Oxford Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50010618 ((+)-3-(1-Propyl-piperidin-3-yl)-phenol \| 3-((R)-1-...) Show SMILES CCCN1CCC[C@@H](C1)c1cccc(O)c1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
University of Oxford Curated by ChEMBL					Assay Description Displacement of (+)-3PPP from sigma receptor of rat brain membrane				J Med Chem 37: 1727-32 (1994) Checked by Author BindingDB Entry DOI: 10.7270/Q25B0408
University of Oxford Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50010618 ((+)-3-(1-Propyl-piperidin-3-yl)-phenol \| 3-((R)-1-...) Show SMILES CCCN1CCC[C@@H](C1)c1cccc(O)c1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Lund Curated by ChEMBL					Assay Description In vitro inhibition of [3H]-spiperone binding to Dopamine receptor D2 in rat striatal membranes				J Med Chem 33: 1015-22 (1990) BindingDB Entry DOI: 10.7270/Q2PV6JBT
University of Lund Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (5HT2A) (Mus musculus (Mouse))	BDBM50010618 ((+)-3-(1-Propyl-piperidin-3-yl)-phenol \| 3-((R)-1-...) Show SMILES CCCN1CCC[C@@H](C1)c1cccc(O)c1 Show InChI	PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	7.61E+4	n/a	n/a	n/a	n/a
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay					Assay Description Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...				PubChem Bioassay (2013) BindingDB Entry DOI: 10.7270/Q24B2ZZ6
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50010618 ((+)-3-(1-Propyl-piperidin-3-yl)-phenol \| 3-((R)-1-...) Show SMILES CCCN1CCC[C@@H](C1)c1cccc(O)c1 Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	9.25E+4	n/a	n/a	n/a	n/a
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay					Assay Description Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Assay Provider: Laura Bohn External Assay ID: OPRM1_AC...				PubChem Bioassay (2013) BindingDB Entry DOI: 10.7270/Q2833QNG
					More data for this Ligand-Target Pair