BDBM50017456 2-Piperazin-1-yl-phenol::CHEMBL266250

SMILES: Oc1ccccc1N1CCNCC1

InChI Key: InChIKey=UORNTHBBLYBAJJ-UHFFFAOYSA-N

Data: 9 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50017456   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50017456 (2-Piperazin-1-yl-phenol | CHEMBL266250) Show SMILES Oc1ccccc1N1CCNCC1 Show InChI InChI=1S/C10H14N2O/c13-10-4-2-1-3-9(10)12-7-5-11-6-8-12/h1-4,11,13H,5-8H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	35	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
McNeil Pharmaceutical and Janssen Research Foundation Worldwide Curated by ChEMBL					Assay Description Binding affinity at rat 5-hydroxytryptamine 1A receptor by [3H]-WB-4101 displacement.				J Med Chem 32: 1052-6 (1989) BindingDB Entry DOI: 10.7270/Q2HD7TNH
					More data for this Ligand-Target Pair
Serotonin 1B/1D receptor (Rattus norvegicus (Rat))	BDBM50017456 (2-Piperazin-1-yl-phenol | CHEMBL266250) Show SMILES Oc1ccccc1N1CCNCC1 Show InChI InChI=1S/C10H14N2O/c13-10-4-2-1-3-9(10)12-7-5-11-6-8-12/h1-4,11,13H,5-8H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	74	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
McNeil Pharmaceutical and Janssen Research Foundation Worldwide Curated by ChEMBL					Assay Description Binding affinity determined in radioreceptor binding assay by using [3H]-5-HT radioligand against 5-hydroxytryptamine 1B receptor				J Med Chem 32: 1052-6 (1989) BindingDB Entry DOI: 10.7270/Q2HD7TNH
					More data for this Ligand-Target Pair
Serotonin 1 (5-HT1) receptor (RAT-Rattus norvegicus (rat)-Rattus norvegicus (Rat...)	BDBM50017456 (2-Piperazin-1-yl-phenol | CHEMBL266250) Show SMILES Oc1ccccc1N1CCNCC1 Show InChI InChI=1S/C10H14N2O/c13-10-4-2-1-3-9(10)12-7-5-11-6-8-12/h1-4,11,13H,5-8H2	PDB MMDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	117	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
McNeil Pharmaceutical and Janssen Research Foundation Worldwide Curated by ChEMBL					Assay Description Binding affinity in radioreceptor binding assay by using [3H]5-HT radioligand against 5-hydroxytryptamine 1 receptor				J Med Chem 32: 1052-6 (1989) BindingDB Entry DOI: 10.7270/Q2HD7TNH
					More data for this Ligand-Target Pair
5-HT5 (MOUSE)	BDBM50017456 (2-Piperazin-1-yl-phenol | CHEMBL266250) Show SMILES Oc1ccccc1N1CCNCC1 Show InChI InChI=1S/C10H14N2O/c13-10-4-2-1-3-9(10)12-7-5-11-6-8-12/h1-4,11,13H,5-8H2	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	215	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Binding affinity towards murine 5-hydroxytryptamine 5A receptor				J Med Chem 46: 2795-812 (2003) Article DOI: 10.1021/jm030030n BindingDB Entry DOI: 10.7270/Q2M0465F
					More data for this Ligand-Target Pair
Alpha-1 Adrenergic Receptor/ adrenergic receptor/ adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat))	BDBM50017456 (2-Piperazin-1-yl-phenol | CHEMBL266250) Show SMILES Oc1ccccc1N1CCNCC1 Show InChI InChI=1S/C10H14N2O/c13-10-4-2-1-3-9(10)12-7-5-11-6-8-12/h1-4,11,13H,5-8H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	516	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
McNeil Pharmaceutical and Janssen Research Foundation Worldwide Curated by ChEMBL					Assay Description Binding affinity against rat Alpha-1 adrenergic receptor.				J Med Chem 32: 1052-6 (1989) BindingDB Entry DOI: 10.7270/Q2HD7TNH
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50017456 (2-Piperazin-1-yl-phenol | CHEMBL266250) Show SMILES Oc1ccccc1N1CCNCC1 Show InChI InChI=1S/C10H14N2O/c13-10-4-2-1-3-9(10)12-7-5-11-6-8-12/h1-4,11,13H,5-8H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
McNeil Pharmaceutical and Janssen Research Foundation Worldwide Curated by ChEMBL					Assay Description Binding affinity against rat Dopamine receptor D2.				J Med Chem 32: 1052-6 (1989) BindingDB Entry DOI: 10.7270/Q2HD7TNH
					More data for this Ligand-Target Pair
Serotonin 2 (5-HT2) receptor (Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...)	BDBM50017456 (2-Piperazin-1-yl-phenol | CHEMBL266250) Show SMILES Oc1ccccc1N1CCNCC1 Show InChI InChI=1S/C10H14N2O/c13-10-4-2-1-3-9(10)12-7-5-11-6-8-12/h1-4,11,13H,5-8H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
McNeil Pharmaceutical and Janssen Research Foundation Worldwide Curated by ChEMBL					Assay Description Binding affinity in radioreceptor binding assay by using [3H]5-HT radioligand against 5-hydroxytryptamine 2 receptor				J Med Chem 32: 1052-6 (1989) BindingDB Entry DOI: 10.7270/Q2HD7TNH
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM50017456 (2-Piperazin-1-yl-phenol | CHEMBL266250) Show SMILES Oc1ccccc1N1CCNCC1 Show InChI InChI=1S/C10H14N2O/c13-10-4-2-1-3-9(10)12-7-5-11-6-8-12/h1-4,11,13H,5-8H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
McNeil Pharmaceutical and Janssen Research Foundation Worldwide Curated by ChEMBL					Assay Description Binding affinity at rat Dopamine receptor D1 by [3H]-SCH-23,390 displacement.				J Med Chem 32: 1052-6 (1989) BindingDB Entry DOI: 10.7270/Q2HD7TNH
					More data for this Ligand-Target Pair
Serotonin 2 (5-HT2) receptor (Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...)	BDBM50017456 (2-Piperazin-1-yl-phenol | CHEMBL266250) Show SMILES Oc1ccccc1N1CCNCC1 Show InChI InChI=1S/C10H14N2O/c13-10-4-2-1-3-9(10)12-7-5-11-6-8-12/h1-4,11,13H,5-8H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	1.72E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]ketanserin from 5-hydroxytryptamine 2 receptor of rat cortex				J Med Chem 29: 630-4 (1986) BindingDB Entry DOI: 10.7270/Q2Z03BCH
					More data for this Ligand-Target Pair