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BDBM50088573 CHEMBL3577208

SMILES: COc1cccc(OC)c1C(=O)c1c(O)cc(C)c(OC)c1C1=C(c2c(C1=O)c(OC)c(C)cc2O)c1c(OC)cccc1OC

InChI Key: InChIKey=XKHQDXVISQSJGT-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50088573   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Voltage-gated potassium channel subunit Kv2.1 (Kv2.1)


(Homo sapiens (Human))		BDBM50088573
PNG
(CHEMBL3577208)
Show SMILES COc1cccc(OC)c1C(=O)c1c(O)cc(C)c(OC)c1C1=C(c2c(C1=O)c(OC)c(C)cc2O)c1c(OC)cccc1OC |t:24|
Show InChI InChI=1S/C36H34O10/c1-17-16-20(38)26(33(39)28-23(43-5)13-10-14-24(28)44-6)31(35(17)45-7)30-29(27-21(41-3)11-9-12-22(27)42-4)25-19(37)15-18(2)36(46-8)32(25)34(30)40/h9-16,37-38H,1-8H3
UniProtKB/SwissProt

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Article
PubMed
n/an/a 590n/an/an/an/an/an/a



Seoul National University

Curated by ChEMBL


Assay Description
Inhibition of Kv2.1 channel in human INS1 cells assessed as inhibition of outward K+ current by electrophysiology/patch clamp technique

J Nat Prod 78: 363-7 (2015)


Article DOI: 10.1021/np5007586
BindingDB Entry DOI: 10.7270/Q20P11R5
More data for this
Ligand-Target Pair