Found 10 hits for monomerid = 50105089 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Delta-type opioid receptor
(Homo sapiens (Human)) | BDBM50105089
(8-Benzo[1,3]dioxol-5-ylmethyl-1-phenyl-1,3,8-triaz...)Show InChI InChI=1S/C21H23N3O3/c25-20-21(24(14-22-20)17-4-2-1-3-5-17)8-10-23(11-9-21)13-16-6-7-18-19(12-16)27-15-26-18/h1-7,12H,8-11,13-15H2,(H,22,25) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 1.19E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
F-59000 Lille
Curated by ChEMBL
| Assay Description Inhibition of ligand binding to human delta opioid receptor. |
J Med Chem 44: 3391-401 (2001)
BindingDB Entry DOI: 10.7270/Q2057GN9 |
More data for this Ligand-Target Pair | |
Delta-type opioid receptor
(Homo sapiens (Human)) | BDBM50105089
(8-Benzo[1,3]dioxol-5-ylmethyl-1-phenyl-1,3,8-triaz...)Show InChI InChI=1S/C21H23N3O3/c25-20-21(24(14-22-20)17-4-2-1-3-5-17)8-10-23(11-9-21)13-16-6-7-18-19(12-16)27-15-26-18/h1-7,12H,8-11,13-15H2,(H,22,25) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 1.19E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
F-59000 Lille
Curated by ChEMBL
| Assay Description Binding affinity against delta-opiate receptor (human) using [3H]-DPDPE radioligand |
J Med Chem 44: 3378-90 (2001)
BindingDB Entry DOI: 10.7270/Q23X87B8 |
More data for this Ligand-Target Pair | |
Kappa-type opioid receptor
(Homo sapiens (Human)) | BDBM50105089
(8-Benzo[1,3]dioxol-5-ylmethyl-1-phenyl-1,3,8-triaz...)Show InChI InChI=1S/C21H23N3O3/c25-20-21(24(14-22-20)17-4-2-1-3-5-17)8-10-23(11-9-21)13-16-6-7-18-19(12-16)27-15-26-18/h1-7,12H,8-11,13-15H2,(H,22,25) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 56 | n/a | n/a | n/a | n/a | n/a | n/a |
F-59000 Lille
Curated by ChEMBL
| Assay Description Binding affinity against opioid receptor kappa 1 using [3H]- U-69,593 radioligand |
J Med Chem 44: 3378-90 (2001)
BindingDB Entry DOI: 10.7270/Q23X87B8 |
More data for this Ligand-Target Pair | |
Mu-type opioid receptor
(Homo sapiens (Human)) | BDBM50105089
(8-Benzo[1,3]dioxol-5-ylmethyl-1-phenyl-1,3,8-triaz...)Show InChI InChI=1S/C21H23N3O3/c25-20-21(24(14-22-20)17-4-2-1-3-5-17)8-10-23(11-9-21)13-16-6-7-18-19(12-16)27-15-26-18/h1-7,12H,8-11,13-15H2,(H,22,25) | PDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 17 | n/a | n/a | n/a | n/a | n/a | n/a |
F-59000 Lille
Curated by ChEMBL
| Assay Description Binding affinity against mu-opiate receptor (human) using [3H]DAMGO radioligand |
J Med Chem 44: 3378-90 (2001)
BindingDB Entry DOI: 10.7270/Q23X87B8 |
More data for this Ligand-Target Pair | |
Mu-type opioid receptor
(Homo sapiens (Human)) | BDBM50105089
(8-Benzo[1,3]dioxol-5-ylmethyl-1-phenyl-1,3,8-triaz...)Show InChI InChI=1S/C21H23N3O3/c25-20-21(24(14-22-20)17-4-2-1-3-5-17)8-10-23(11-9-21)13-16-6-7-18-19(12-16)27-15-26-18/h1-7,12H,8-11,13-15H2,(H,22,25) | PDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 17 | n/a | n/a | n/a | n/a | n/a | n/a |
F-59000 Lille
Curated by ChEMBL
| Assay Description Binding affinity against mu opiate receptor |
J Med Chem 44: 3391-401 (2001)
BindingDB Entry DOI: 10.7270/Q2057GN9 |
More data for this Ligand-Target Pair | |
D(4) dopamine receptor
(Homo sapiens (Human)) | BDBM50105089
(8-Benzo[1,3]dioxol-5-ylmethyl-1-phenyl-1,3,8-triaz...)Show InChI InChI=1S/C21H23N3O3/c25-20-21(24(14-22-20)17-4-2-1-3-5-17)8-10-23(11-9-21)13-16-6-7-18-19(12-16)27-15-26-18/h1-7,12H,8-11,13-15H2,(H,22,25) | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 947 | n/a | n/a | n/a | n/a | n/a | n/a |
F-59000 Lille
Curated by ChEMBL
| Assay Description Inhibition of human dopamine receptor D4.4 |
J Med Chem 44: 3391-401 (2001)
BindingDB Entry DOI: 10.7270/Q2057GN9 |
More data for this Ligand-Target Pair | |
D(3) dopamine receptor
(Homo sapiens (Human)) | BDBM50105089
(8-Benzo[1,3]dioxol-5-ylmethyl-1-phenyl-1,3,8-triaz...)Show InChI InChI=1S/C21H23N3O3/c25-20-21(24(14-22-20)17-4-2-1-3-5-17)8-10-23(11-9-21)13-16-6-7-18-19(12-16)27-15-26-18/h1-7,12H,8-11,13-15H2,(H,22,25) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 160 | n/a | n/a | n/a | n/a | n/a | n/a |
F-59000 Lille
Curated by ChEMBL
| Assay Description Inhibition of human dopamine receptor D3 |
J Med Chem 44: 3391-401 (2001)
BindingDB Entry DOI: 10.7270/Q2057GN9 |
More data for this Ligand-Target Pair | |
Nociceptin receptor
(Homo sapiens (Human)) | BDBM50105089
(8-Benzo[1,3]dioxol-5-ylmethyl-1-phenyl-1,3,8-triaz...)Show InChI InChI=1S/C21H23N3O3/c25-20-21(24(14-22-20)17-4-2-1-3-5-17)8-10-23(11-9-21)13-16-6-7-18-19(12-16)27-15-26-18/h1-7,12H,8-11,13-15H2,(H,22,25) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 340 | n/a | n/a | n/a | n/a | n/a | n/a |
F-59000 Lille
Curated by ChEMBL
| Assay Description Inhibition of human ORL1 orphanin receptor |
J Med Chem 44: 3391-401 (2001)
BindingDB Entry DOI: 10.7270/Q2057GN9 |
More data for this Ligand-Target Pair | |
Kappa-type opioid receptor
(Homo sapiens (Human)) | BDBM50105089
(8-Benzo[1,3]dioxol-5-ylmethyl-1-phenyl-1,3,8-triaz...)Show InChI InChI=1S/C21H23N3O3/c25-20-21(24(14-22-20)17-4-2-1-3-5-17)8-10-23(11-9-21)13-16-6-7-18-19(12-16)27-15-26-18/h1-7,12H,8-11,13-15H2,(H,22,25) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 56 | n/a | n/a | n/a | n/a | n/a | n/a |
F-59000 Lille
Curated by ChEMBL
| Assay Description Binding affinity against opioid receptor kappa 1 by using [3H]U-69593 as radioligand |
J Med Chem 44: 3391-401 (2001)
BindingDB Entry DOI: 10.7270/Q2057GN9 |
More data for this Ligand-Target Pair | |
D(2) dopamine receptor
(Homo sapiens (Human)) | BDBM50105089
(8-Benzo[1,3]dioxol-5-ylmethyl-1-phenyl-1,3,8-triaz...)Show InChI InChI=1S/C21H23N3O3/c25-20-21(24(14-22-20)17-4-2-1-3-5-17)8-10-23(11-9-21)13-16-6-7-18-19(12-16)27-15-26-18/h1-7,12H,8-11,13-15H2,(H,22,25) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 557 | n/a | n/a | n/a | n/a | n/a | n/a |
F-59000 Lille
Curated by ChEMBL
| Assay Description Inhibition of human dopamine receptor D2 |
J Med Chem 44: 3391-401 (2001)
BindingDB Entry DOI: 10.7270/Q2057GN9 |
More data for this Ligand-Target Pair | |