BDBM50130594 3-[4-(4-Hydroxy-3-isopropyl-benzyl)-3,5-dimethyl-phenyl]-propionic acid::CHEMBL322361

SMILES: CC(C)c1cc(Cc2c(C)cc(CCC(O)=O)cc2C)ccc1O

InChI Key: InChIKey=ATPKCBHYEIYBSL-UHFFFAOYSA-N

Data: 2 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50130594   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Thyroid hormone receptor alpha (Homo sapiens (Human))	BDBM50130594 (3-[4-(4-Hydroxy-3-isopropyl-benzyl)-3,5-dimethyl-p...) Show SMILES CC(C)c1cc(Cc2c(C)cc(CCC(O)=O)cc2C)ccc1O Show InChI InChI=1S/C21H26O3/c1-13(2)18-11-17(5-7-20(18)22)12-19-14(3)9-16(10-15(19)4)6-8-21(23)24/h5,7,9-11,13,22H,6,8,12H2,1-4H3,(H,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	0.690	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Binding affinity of compound was determined against Thyroid hormone receptor alpha1				J Med Chem 46: 3152-61 (2003) Article DOI: 10.1021/jm0301181 BindingDB Entry DOI: 10.7270/Q2NK3DF9
					More data for this Ligand-Target Pair
Thyroid hormone receptor beta (Homo sapiens (Human))	BDBM50130594 (3-[4-(4-Hydroxy-3-isopropyl-benzyl)-3,5-dimethyl-p...) Show SMILES CC(C)c1cc(Cc2c(C)cc(CCC(O)=O)cc2C)ccc1O Show InChI InChI=1S/C21H26O3/c1-13(2)18-11-17(5-7-20(18)22)12-19-14(3)9-16(10-15(19)4)6-8-21(23)24/h5,7,9-11,13,22H,6,8,12H2,1-4H3,(H,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	0.220	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Binding affinity of compound was determined against thyroid hormone receptor beta 1				J Med Chem 46: 3152-61 (2003) Article DOI: 10.1021/jm0301181 BindingDB Entry DOI: 10.7270/Q2NK3DF9
					More data for this Ligand-Target Pair