BDBM50171474 CHEMBL192662::[3-[2-(1,1-Diphenyl-ethylsulfanyl)-ethyl]-2-(2-hydroxy-ethyl)-benzofuran-7-yloxy]-acetic acid
SMILES: CC(SCCc1c(CCO)oc2c(OCC(O)=O)cccc12)(c1ccccc1)c1ccccc1
InChI Key: InChIKey=RFHFLABUEIMYLC-UHFFFAOYSA-N
Data: 2 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Prostanoid TP receptor (Homo sapiens (Human)) | BDBM50171474 (CHEMBL192662 | [3-[2-(1,1-Diphenyl-ethylsulfanyl)-...) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 78 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Toray Industries Inc. Curated by ChEMBL | Assay Description Inhibition of [3H]-SQ-29,548 binding to thromboxane A2 receptors (TP) of human platelet membrane | J Med Chem 48: 5279-94 (2005) Article DOI: 10.1021/jm050194z BindingDB Entry DOI: 10.7270/Q2J67GGC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostanoid IP receptor (Homo sapiens (Human)) | BDBM50171474 (CHEMBL192662 | [3-[2-(1,1-Diphenyl-ethylsulfanyl)-...) | NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 210 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Toray Industries Inc. Curated by ChEMBL | Assay Description Inhibition of [3H]-APS-314d binding to prostacyclin receptors (IP) of human platelet membrane | J Med Chem 48: 5279-94 (2005) Article DOI: 10.1021/jm050194z BindingDB Entry DOI: 10.7270/Q2J67GGC | |||||||||||
More data for this Ligand-Target Pair |