BDBM50185446 (E)-1-(2,4-dihydroxy-6-methoxyphenyl)-3-phenylprop-2-en-1-one::CHEMBL378104::cardamomin::cardamonin

SMILES: COc1cc(O)cc(O)c1C(=O)\C=C\c1ccccc1

InChI Key: InChIKey=NYSZJNUIVUBQMM-BQYQJAHWSA-N

Data: 1 KI  3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50185446   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dengue virus type 2 NS3 protein (Dengue virus 2)	BDBM50185446 ((E)-1-(2,4-dihydroxy-6-methoxyphenyl)-3-phenylprop...) Show SMILES COc1cc(O)cc(O)c1C(=O)\C=C\c1ccccc1 Show InChI InChI=1S/C16H14O4/c1-20-15-10-12(17)9-14(19)16(15)13(18)8-7-11-5-3-2-4-6-11/h2-10,17,19H,1H3/b8-7+	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	3.77E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Sunway University College Curated by ChEMBL					Assay Description Inhibition of dengue2 virus NS3 protease				Bioorg Med Chem Lett 16: 3337-40 (2006) Article DOI: 10.1016/j.bmcl.2005.12.075 BindingDB Entry DOI: 10.7270/Q2FN16ZM
					More data for this Ligand-Target Pair
Protease (Human immunodeficiency virus 1 (HIV-1))	BDBM50185446 ((E)-1-(2,4-dihydroxy-6-methoxyphenyl)-3-phenylprop...) Show SMILES COc1cc(O)cc(O)c1C(=O)\C=C\c1ccccc1 Show InChI InChI=1S/C16H14O4/c1-20-15-10-12(17)9-14(19)16(15)13(18)8-7-11-5-3-2-4-6-11/h2-10,17,19H,1H3/b8-7+	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.14E+5	n/a	n/a	n/a	n/a	n/a	n/a
Adam Mickiewicz University Curated by ChEMBL					Assay Description Inhibition of HIV1 protease				Eur J Med Chem 42: 125-37 (2007) Article DOI: 10.1016/j.ejmech.2006.09.019 BindingDB Entry DOI: 10.7270/Q2CF9SW3
					More data for this Ligand-Target Pair
Voltage-gated potassium channel (Homo sapiens (Human))	BDBM50185446 ((E)-1-(2,4-dihydroxy-6-methoxyphenyl)-3-phenylprop...) Show SMILES COc1cc(O)cc(O)c1C(=O)\C=C\c1ccccc1 Show InChI InChI=1S/C16H14O4/c1-20-15-10-12(17)9-14(19)16(15)13(18)8-7-11-5-3-2-4-6-11/h2-10,17,19H,1H3/b8-7+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	740	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Research and Development Curated by ChEMBL					Assay Description Inhibition of human voltage-gated potassium channel Kv1.3 expressed in CGE22 cells by patch clamp assay				Bioorg Med Chem Lett 20: 6983-8 (2010) Article DOI: 10.1016/j.bmcl.2010.09.132 BindingDB Entry DOI: 10.7270/Q2N58MMS
					More data for this Ligand-Target Pair
Voltage-gated potassium channel (Homo sapiens (Human))	BDBM50185446 ((E)-1-(2,4-dihydroxy-6-methoxyphenyl)-3-phenylprop...) Show SMILES COc1cc(O)cc(O)c1C(=O)\C=C\c1ccccc1 Show InChI InChI=1S/C16H14O4/c1-20-15-10-12(17)9-14(19)16(15)13(18)8-7-11-5-3-2-4-6-11/h2-10,17,19H,1H3/b8-7+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Research and Development Curated by ChEMBL					Assay Description Inhibition of human voltage-gated potassium channel Kv1.3 expressed in L929 cells by whole-cell patch clamp assay				Bioorg Med Chem Lett 20: 6983-8 (2010) Article DOI: 10.1016/j.bmcl.2010.09.132 BindingDB Entry DOI: 10.7270/Q2N58MMS
					More data for this Ligand-Target Pair