BDBM50201338 7-methyl-6,7,8,9,14,15-hexahydro-5H-indolo[3,2-f][3]benzazecin-11-ol::CHEMBL245570

SMILES: CN1CCc2c(Cc3ccccc3CC1)[nH]c1ccc(O)cc21

InChI Key: InChIKey=UPTHGVUSCNDAPF-UHFFFAOYSA-N

Data: 6 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50201338   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(1B) dopamine receptor (Homo sapiens (Human))	BDBM50201338 (7-methyl-6,7,8,9,14,15-hexahydro-5H-indolo[3,2-f][...) Show SMILES CN1CCc2c(Cc3ccccc3CC1)[nH]c1ccc(O)cc21 Show InChI InChI=1S/C20H22N2O/c1-22-10-8-14-4-2-3-5-15(14)12-20-17(9-11-22)18-13-16(23)6-7-19(18)21-20/h2-7,13,21,23H,8-12H2,1H3	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.390	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Schiller-Universität Jena Curated by ChEMBL					Assay Description Binding affinity to human cloned dopamine D5 receptor expressed in HEK 293 cells				Bioorg Med Chem Lett 17: 1399-402 (2007) Article DOI: 10.1016/j.bmcl.2006.11.093 BindingDB Entry DOI: 10.7270/Q24T6J1G
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM50201338 (7-methyl-6,7,8,9,14,15-hexahydro-5H-indolo[3,2-f][...) Show SMILES CN1CCc2c(Cc3ccccc3CC1)[nH]c1ccc(O)cc21 Show InChI InChI=1S/C20H22N2O/c1-22-10-8-14-4-2-3-5-15(14)12-20-17(9-11-22)18-13-16(23)6-7-19(18)21-20/h2-7,13,21,23H,8-12H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.560	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Schiller-Universität Jena Curated by ChEMBL					Assay Description Displacement of [3H]SCH 23390 from human cloned dopamine D1 receptor expressed in HEK 293 cells				Bioorg Med Chem Lett 17: 1399-402 (2007) Article DOI: 10.1016/j.bmcl.2006.11.093 BindingDB Entry DOI: 10.7270/Q24T6J1G
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM50201338 (7-methyl-6,7,8,9,14,15-hexahydro-5H-indolo[3,2-f][...) Show SMILES CN1CCc2c(Cc3ccccc3CC1)[nH]c1ccc(O)cc21 Show InChI InChI=1S/C20H22N2O/c1-22-10-8-14-4-2-3-5-15(14)12-20-17(9-11-22)18-13-16(23)6-7-19(18)21-20/h2-7,13,21,23H,8-12H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.562	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Schiller-Universit£t Jena Curated by ChEMBL					Assay Description Displacement of [3H]SCH23390 from human cloned dopamine D1 receptor				Bioorg Med Chem Lett 18: 3809-13 (2008) Article DOI: 10.1016/j.bmcl.2008.04.081 BindingDB Entry DOI: 10.7270/Q23F4QWW
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50201338 (7-methyl-6,7,8,9,14,15-hexahydro-5H-indolo[3,2-f][...) Show SMILES CN1CCc2c(Cc3ccccc3CC1)[nH]c1ccc(O)cc21 Show InChI InChI=1S/C20H22N2O/c1-22-10-8-14-4-2-3-5-15(14)12-20-17(9-11-22)18-13-16(23)6-7-19(18)21-20/h2-7,13,21,23H,8-12H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	38.4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Schiller-Universität Jena Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from human cloned dopamine D2L receptor expressed in CHO cells				Bioorg Med Chem Lett 17: 1399-402 (2007) Article DOI: 10.1016/j.bmcl.2006.11.093 BindingDB Entry DOI: 10.7270/Q24T6J1G
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50201338 (7-methyl-6,7,8,9,14,15-hexahydro-5H-indolo[3,2-f][...) Show SMILES CN1CCc2c(Cc3ccccc3CC1)[nH]c1ccc(O)cc21 Show InChI InChI=1S/C20H22N2O/c1-22-10-8-14-4-2-3-5-15(14)12-20-17(9-11-22)18-13-16(23)6-7-19(18)21-20/h2-7,13,21,23H,8-12H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	43.6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Schiller-Universit£t Jena Curated by ChEMBL					Assay Description Displacement of [3H]SCH23390 from human cloned dopamine D2L receptor				Bioorg Med Chem Lett 18: 3809-13 (2008) Article DOI: 10.1016/j.bmcl.2008.04.081 BindingDB Entry DOI: 10.7270/Q23F4QWW
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50201338 (7-methyl-6,7,8,9,14,15-hexahydro-5H-indolo[3,2-f][...) Show SMILES CN1CCc2c(Cc3ccccc3CC1)[nH]c1ccc(O)cc21 Show InChI InChI=1S/C20H22N2O/c1-22-10-8-14-4-2-3-5-15(14)12-20-17(9-11-22)18-13-16(23)6-7-19(18)21-20/h2-7,13,21,23H,8-12H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	944	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Schiller-Universität Jena Curated by ChEMBL					Assay Description Binding affinity to human cloned dopamine D3 receptor expressed in CHO cells				Bioorg Med Chem Lett 17: 1399-402 (2007) Article DOI: 10.1016/j.bmcl.2006.11.093 BindingDB Entry DOI: 10.7270/Q24T6J1G
					More data for this Ligand-Target Pair