BDBM50280030 (2S,3R,4R,5S)-2-Fluoromethyl-piperidine-3,4,5-triol::CHEMBL111326
SMILES: O[C@H]1CN[C@H](CF)[C@@H](O)[C@@H]1O
InChI Key: InChIKey=GRCJBMPQQMMCPE-JGWLITMVSA-N
Data: 7 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Neutral alpha-glucosidase AB (Homo sapiens (Human)) | BDBM50280030 ((2S,3R,4R,5S)-2-Fluoromethyl-piperidine-3,4,5-trio...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article | 8.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | 8.0 | n/a |
TBA Curated by ChEMBL | Assay Description Competitive Inhibition constant of the compound was determined on yeast alpha Glucosidase at pH 7.0 | Bioorg Med Chem Lett 2: 27-32 (1992) Article DOI: 10.1016/S0960-894X(00)80648-4 BindingDB Entry DOI: 10.7270/Q2TH8MKB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neutral alpha-glucosidase AB (Homo sapiens (Human)) | BDBM50280030 ((2S,3R,4R,5S)-2-Fluoromethyl-piperidine-3,4,5-trio...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article | 1.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a | 5.0 | n/a |
TBA Curated by ChEMBL | Assay Description Competitive Inhibition constant of the compound was determined on yeast alpha Glucosidase at pH 5.0 | Bioorg Med Chem Lett 2: 27-32 (1992) Article DOI: 10.1016/S0960-894X(00)80648-4 BindingDB Entry DOI: 10.7270/Q2TH8MKB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neutral alpha-glucosidase AB (Homo sapiens (Human)) | BDBM50280030 ((2S,3R,4R,5S)-2-Fluoromethyl-piperidine-3,4,5-trio...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article | 2.90E+4 | n/a | n/a | n/a | n/a | n/a | n/a | 6.0 | n/a |
TBA Curated by ChEMBL | Assay Description Competitive Inhibition constant of the compound was determined on rice alpha Glucosidase at pH 5.0 | Bioorg Med Chem Lett 2: 27-32 (1992) Article DOI: 10.1016/S0960-894X(00)80648-4 BindingDB Entry DOI: 10.7270/Q2TH8MKB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neutral alpha-glucosidase AB (Homo sapiens (Human)) | BDBM50280030 ((2S,3R,4R,5S)-2-Fluoromethyl-piperidine-3,4,5-trio...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article | 4.70E+4 | n/a | n/a | n/a | n/a | n/a | n/a | 7.0 | n/a |
TBA Curated by ChEMBL | Assay Description Competitive Inhibition constant of the compound was determined on Asp. Wentii beta Glucosidase at pH 5.0 | Bioorg Med Chem Lett 2: 27-32 (1992) Article DOI: 10.1016/S0960-894X(00)80648-4 BindingDB Entry DOI: 10.7270/Q2TH8MKB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neutral alpha-glucosidase AB (Homo sapiens (Human)) | BDBM50280030 ((2S,3R,4R,5S)-2-Fluoromethyl-piperidine-3,4,5-trio...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article | 3.40E+5 | n/a | n/a | n/a | n/a | n/a | n/a | 7.0 | n/a |
TBA Curated by ChEMBL | Assay Description Competitive Inhibition constant of the compound was determined on yeast alpha Glucosidase at pH 7.0 | Bioorg Med Chem Lett 2: 27-32 (1992) Article DOI: 10.1016/S0960-894X(00)80648-4 BindingDB Entry DOI: 10.7270/Q2TH8MKB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysosomal acid glucosylceramidase (Homo sapiens (Human)) | BDBM50280030 ((2S,3R,4R,5S)-2-Fluoromethyl-piperidine-3,4,5-trio...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article | 3.80E+5 | n/a | n/a | n/a | n/a | n/a | n/a | 5.0 | n/a |
TBA Curated by ChEMBL | Assay Description Competitive Inhibition constant of the compound was determined on Asp. Wentii beta Glucosidase at pH 5.0 | Bioorg Med Chem Lett 2: 27-32 (1992) Article DOI: 10.1016/S0960-894X(00)80648-4 BindingDB Entry DOI: 10.7270/Q2TH8MKB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysosomal acid glucosylceramidase (Homo sapiens (Human)) | BDBM50280030 ((2S,3R,4R,5S)-2-Fluoromethyl-piperidine-3,4,5-trio...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article | 6.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a | 5.0 | n/a |
TBA Curated by ChEMBL | Assay Description Competitive Inhibition constant of the compound was determined on yeast alpha Glucosidase at pH 5.0 | Bioorg Med Chem Lett 2: 27-32 (1992) Article DOI: 10.1016/S0960-894X(00)80648-4 BindingDB Entry DOI: 10.7270/Q2TH8MKB | |||||||||||
More data for this Ligand-Target Pair |