Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Lysosomal acid glucosylceramidase (Homo sapiens (Human)) | BDBM50280030 ((2S,3R,4R,5S)-2-Fluoromethyl-piperidine-3,4,5-trio...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article | 3.80E+5 | n/a | n/a | n/a | n/a | n/a | n/a | 5.0 | n/a |
TBA Curated by ChEMBL | Assay Description Competitive Inhibition constant of the compound was determined on Asp. Wentii beta Glucosidase at pH 5.0 | Bioorg Med Chem Lett 2: 27-32 (1992) Article DOI: 10.1016/S0960-894X(00)80648-4 BindingDB Entry DOI: 10.7270/Q2TH8MKB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysosomal acid glucosylceramidase (Homo sapiens (Human)) | BDBM50280030 ((2S,3R,4R,5S)-2-Fluoromethyl-piperidine-3,4,5-trio...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article | 6.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a | 5.0 | n/a |
TBA Curated by ChEMBL | Assay Description Competitive Inhibition constant of the compound was determined on yeast alpha Glucosidase at pH 5.0 | Bioorg Med Chem Lett 2: 27-32 (1992) Article DOI: 10.1016/S0960-894X(00)80648-4 BindingDB Entry DOI: 10.7270/Q2TH8MKB | |||||||||||
More data for this Ligand-Target Pair |