BDBM50311316 CHEMBL1077739::LDN-211904::N-(2-chlorophenyl)-6-(piperidin-4-yl)imidazo[1,2-a]pyridine-3-carboxamide, oxalate salt

SMILES: Clc1ccccc1NC(=O)c1cnc2ccc(cn12)C1CCNCC1

InChI Key: InChIKey=DGSMEFWSLXFLQA-UHFFFAOYSA-N

Data: 2 IC50  1 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50311316   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ephrin type-A receptor 2 (EPHA2) (Homo sapiens (Human))	BDBM50311316 (CHEMBL1077739 | LDN-211904 | N-(2-chlorophenyl)-6-...) Show SMILES Clc1ccccc1NC(=O)c1cnc2ccc(cn12)C1CCNCC1 Show InChI InChI=1S/C19H19ClN4O/c20-15-3-1-2-4-16(15)23-19(25)17-11-22-18-6-5-14(12-24(17)18)13-7-9-21-10-8-13/h1-6,11-13,21H,7-10H2,(H,23,25)	PDB GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	165	n/a	n/a	n/a	n/a	n/a
Technical University of Munich					Assay Description Kinobeads competition assays were performed in 96-well format as previously described using mixed protein lysates of four cancer cell lines (K-562, M...				ACS Chem Biol 11: 3400-3411 (2016) Article DOI: 10.1021/acschembio.6b00709 BindingDB Entry DOI: 10.7270/Q2TD9W5M
					More data for this Ligand-Target Pair
Ephrin type-B receptor 3 (EPHB3) (Homo sapiens (Human))	BDBM50311316 (CHEMBL1077739 | LDN-211904 | N-(2-chlorophenyl)-6-...) Show SMILES Clc1ccccc1NC(=O)c1cnc2ccc(cn12)C1CCNCC1 Show InChI InChI=1S/C19H19ClN4O/c20-15-3-1-2-4-16(15)23-19(25)17-11-22-18-6-5-14(12-24(17)18)13-7-9-21-10-8-13/h1-6,11-13,21H,7-10H2,(H,23,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	79	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Inhibition of human recombinant EphB3 kinase-mediated BTK-peptide phosphorylation assessed as 33P incorporation after 30 mins by scintillation counti...				Bioorg Med Chem Lett 19: 6122-6 (2009) Article DOI: 10.1016/j.bmcl.2009.09.010 BindingDB Entry DOI: 10.7270/Q2T43T66
					More data for this Ligand-Target Pair
Ephrin type-A receptor 2 (EPHA2) (Homo sapiens (Human))	BDBM50311316 (CHEMBL1077739 | LDN-211904 | N-(2-chlorophenyl)-6-...) Show SMILES Clc1ccccc1NC(=O)c1cnc2ccc(cn12)C1CCNCC1 Show InChI InChI=1S/C19H19ClN4O/c20-15-3-1-2-4-16(15)23-19(25)17-11-22-18-6-5-14(12-24(17)18)13-7-9-21-10-8-13/h1-6,11-13,21H,7-10H2,(H,23,25)	PDB GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.10	n/a	n/a	n/a	n/a	n/a	n/a
Technical University of Munich					Assay Description Refer to Reaction Biology Corps.				ACS Chem Biol 11: 3400-3411 (2016) Article DOI: 10.1021/acschembio.6b00709 BindingDB Entry DOI: 10.7270/Q2TD9W5M
					More data for this Ligand-Target Pair